13.07.2015 Views

Guidelines for Complications of Cancer Treatment Vol VIII Part B

Guidelines for Complications of Cancer Treatment Vol VIII Part B

Guidelines for Complications of Cancer Treatment Vol VIII Part B

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<strong>Complications</strong> <strong>of</strong> Abdomino-PelvicRadiotherapyIntroduction:Radiation therapy is an established treatment modality in themanagement <strong>of</strong> patients with gynecological, gastrointestinaland genitourinary malignancies. The radiation can be eitherexternal beam (teletherapy) alone, internal (brachytherapy)or combination. Radiation therapy (external alone orcombination <strong>of</strong> external and brachytherapy) is given indifferent settings depending on the intent <strong>of</strong> treatment. It couldbe in radical radiation, post or peri-operative adjuvant, salvageor palliative settings. In recent past there has been a paradigmshift towards use <strong>of</strong> concomitant chemoradiation <strong>for</strong>radiosensitization. The classical example to illustrate use <strong>of</strong>radiation in various settings is cervical cancers. In stage II/IIIcervical cancers radical radiation therapy with / withoutconcomitant chemotherapy is the treatment <strong>of</strong> choice.Radiation is also given as adjuvant postoperative treatment inpatients with high risk histo-pathological features like, tumorsize, positive margins, lymphovascular invasion or positivelymph nodes in cervical and endometrial cancers after radicalsurgery and risk stratification . In cases where para aortic lymph263

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