Marie Curie Actions: Inspiring Researchers - Imdea

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NUCSYSComplex organisms such as human beings are made up of tens of trillions of individual cells – quite a complicatedset-up, by any standard. When communication between these various parts fails, system-wide breakdown canfollow. The academic and industrial partners within the NucSys research training network have set themselves thetask of understanding how to avoid such a scenario.
Broadeningcooperation to tacklediet and diseaseThe network includes leading academic and industrial partnersfrom nine EU countries. Its success provides clear evidence ofthe importance of cooperation and exchange between all of thoseworking in the wider medical research community.Cells perceive and respond to their environment. They triggerphysical development, enable wounds to heal and kick-startthe immune system into action when the body is under attackfrom a virus. NucSys is seeking to understand the infl uenceof nutrients contained in the food we eat on the behaviour ofcells in the human body.The starting point for NucSys is one of the key players inintercellular communication – nuclear receptors. These canbe found within the cells that mediate the activity of hormonesand other substances, including certain vitamins.‘Nuclear receptors constitute a large network in the human body,’explains Dr Carsten Carlberg of the University of Luxembourg.‘They sense lipids, carbohydrates and cholesterol compounds,and assess overall energetic status. They also prompt amultitude of responses.’ Nuclear receptors, in concert withother proteins, regulate how genes work, he explains. ‘Theytrigger cell growth, changes in metabolic rate and homeostasis,among other things.’As with many physiological processes, the ways in which thegenes respond are subtle, affected by other biological functionsand given conditions. But when disease strikes, the normalworking relationship between the sensors and the responsenetworks is disrupted. Dr Carlberg says a better understandingof these processes could lead to novel insights into how toimprove health.133
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EUROPEANCOMMISSIONEuropeanResearch
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EUROPEAN COMMISSIONINSPIRING RESEAR
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Marie Curie Actions: Inspiring Rese
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ContentsIntroduction . . . . . . .
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WORLDWIDE RESEARCH . . . . . . . .
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within the best European research g
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Cross-border cooperation is the cor
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The Marie Curie programme seeks to
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AQUACHEMWater is life. It is key to
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ground for early-stage and experien
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CARBIOCarbon nanotubes are the epit
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e chemically modifi ed to further e
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CATALYSTS TOMOGRAPHY‘Everything b
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included a specimen holder inserted
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CRONUS-EUThe Earth is under attack:
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led to an unprecedented ability to
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HETEROLICSThe days of grainy graphi
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Other researchers from Ural State T
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HYDROGEN 1S-2SAccurate clocks are c
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more accurate. Such a clock could b
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RAPTOR ECOTOXFears over species los
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in Sicily, as well as rock climbers
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SMARTEverything about this material
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Development scheme as a chance to m
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SPATSTATHow can statistical analysi
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Hristopulos. There are two categori
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TRACKSResearch within the Tracks pr
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intellectual property issues and th
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Marie Curie Fellowships act as a sp
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The seeds of a budding career are p
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ARTEMISUnderstanding nature at its
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network institutes have allowed the
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BIOMEMA membrane is a layer of mate
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Mighty Mini-MBABut Biomem also step
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COMODEWhen consumers buy a new coff
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with computer-aided design (CAD) to
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COOPERATIVE BREEDINGCan our sibling
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mammals. Other analyses of cooperat
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CSIMHVALVESImagine being able to un
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could be used to describe how carti
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GLUESDr Markus Reichstein is a ‘r
Page 84 and 85: The carbon cycle begins with plants
Page 86 and 87: INTERDECHow an organism develops de
Page 88 and 89: The heart of the matterThe PhD Fell
Page 90 and 91: KAPROWThe theory of democratic peac
Page 92 and 93: necessary to stop it.’ If we are
Page 94 and 95: NASCENTAlthough nanotechnology deal
Page 96 and 97: The network focuses on the developm
Page 98 and 99: NEUROEMPATHYEver sense a chill runn
Page 100 and 101: Mapping empathySince the 1890s, it
Page 102 and 103: © stock.xchngOESTROGEN RECEPTORThe
Page 104 and 105: says Dr López-Béjar. Underlining
Page 106 and 107: PAPHOSIn 1870, Jules Verne wrote ab
Page 108 and 109: Minuscule communities under the sea
Page 110 and 111: PENELOPEPenelope, the wife of Ulyss
Page 112 and 113: Training and travelFor the Fellows,
Page 114 and 115: PUMPING UP THE HEARTMany researcher
Page 116 and 117: iochemical reactions take place in
Page 118 and 119: SEMEAIOutside the obvious green job
Page 120 and 121: suited to some companies than to ot
Page 122 and 123: Increasing our knowledge of the uni
Page 124 and 125: Everybody benefi ts from knowledge
Page 126 and 127: CABMarie Curie Fellows working unde
Page 128 and 129: The project achieved some major mil
Page 130 and 131: ENZYMATEnzymes are biomolecules tha
Page 132 and 133: eports. And the industry seems to s
Page 136 and 137: Integrating the ‘-omics’Nuclear
Page 138 and 139: TARGET-BREASTThe emotional turmoil
Page 140 and 141: diagnostics within an industrial en
Page 142 and 143: TEAMOHOLICAlthough it deals with an
Page 144 and 145: Dream teamAs its name suggests, Tea
Page 146 and 147: Women researchers have brought majo
Page 148 and 149: more likely to leave once they are
Page 150 and 151: AQUABASEToday, an increasingly comp
Page 152 and 153: ‘With C14 isotopes, we can track
Page 154 and 155: DRUG-DISCOVERYDuring her two-year M
Page 156 and 157: chemically in various fashions. The
Page 158 and 159: EARA-ESTThe European Association fo
Page 160 and 161: ‘Our programme is founded on the
Page 162 and 163: GLADNETAccurate data about the qual
Page 164 and 165: Working with industryIn addition to
Page 166 and 167: MIGRANT CHILDRENImmigration has bec
Page 168 and 169: Ireland possesses a category of mig
Page 170 and 171: NANBIOPTICOne of the most exciting
Page 172 and 173: Marie Curie support allowed me, amo
Page 174 and 175: NANOMATCHDeveloping new and more ef
Page 176 and 177: ‘The ombudswoman is used quite fr
Page 178 and 179: Europe is increasingly retaining it
Page 180 and 181: well as the researcher’s scientif
Page 182 and 183: ADAPTUNPREDICTThe Marie Curie progr
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we understand the consequences bett
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© stock.xchngCSS-OMICSStress is a
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A key part of her research was to f
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ELSAQUINTANA-NCSCSFor Spanish pharm
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The cancer stem cell hypothesis pre
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EXNER_BORISOVMany modern devices an
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chips, for instance. ‘Of course,
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HIVOXFORDIn late 2006, five Bulgari
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that the accused medical personnel
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© stock.xchngMARINE MAGNETISMIsn
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aeolian dust. The second traces dus
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MODPAPThe Modpap project has delive
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According to Dr Macpherson, Dr Pill
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NANOSWITCHIt calls to mind a scene
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‘Throughout their journey, the na
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PIPKIGKOOne in every 700 babies bor
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focal adhesions of specifi c protei
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TARGETING PCD IN PDA Marie Curie gr
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the blood-brain barrier, the precur
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Science completely shapes the way w
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as labs and microscopes in order to
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BCRThe moon holds a strange fascina
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A new perspective on chronobiologyT
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© stock.xchngBIMORESolar energy is
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convert CO 2into a reduced carbon b
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CENS-CMAAs the Estonian coastline c
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The research visitors provided valu
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FLOODSVery few of us now question t
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The hunting ground for this preciou
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NANOMAG-LABThese days, the average
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What is more, Nanomag-Lab fostered
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NEPHILID SPIDERSSlovenian scientist
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One simple strategy involves the ma
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© stock.xchngWISEThe 32 countries
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and-tested methodology also include
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The quest for knowledge is a univer
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Global partnershipsBy opening up Eu
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ATTACCOnly one in a million is affe
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nutrients and ensures blood supply
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BIOSEBOut in the middle of nowhere,
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free discussion evenings, and staff
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CAUSE KIDNEY DAMAGEA potentially de
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might contribute to the effect. ‘
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CAVEOLINSEvery breath becomes a whe
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‘Our research revealed that the c
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EPISCONThe conservation and preserv
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able to follow whatever course my c
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© stock.xchngPARSEMUnder the Marie
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The research objectives of Parsem w
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NEURAL CIRCUITBlind mice can now se
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An international effortRecognising
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Being able to simultaneously build
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A number of initiatives can be impl
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EURYTHRONYoung researchers working
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Flexible work environmentThe resear
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INNATE IMMUNITYThe Innate Immunity
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more cytokines. Normally, this feed
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NLRS IN IMMUNITYMore than a million
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organisms and to shed light on the
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ZSN-PHD PROGRAMMEIt takes talent, t
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eview.’ The ZSN has also encourag
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The Marie Curie Actions are founded
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All this is designed to achieve one
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On soft groundWhen faced with groun
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shared through annual workshops, in
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And the Oscar goesto...When your ci
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this, the software can take charact
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Recreating the earlyuniverseParticl
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Imagination equals discoveryDr Mast
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Rock-solid researchinto shaky groun
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existing ones with international sc
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Wireless wisdomComputer networks ha
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he recently received a Young Invest
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It’s elementary:of quarks, lepton
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A real career boostAdding into the
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Spin,little electron, spinAt the ba
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The armamentarium for new researchT
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Putting an endto cluster bombtraged
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elations, law and politics from the
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Inspiring changein the wider resear
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343
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Good vibrationsThe Marie Curie Acti
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to signifi cantly change the way Ph
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MuTra: a labour of loveWhile the ge
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sites in Berlin, Munich, Zürich, S
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The Marie Curie Actions are widely
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Marie Curie Actions: Inspiring Researchers - Imdea

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