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Thursday January 26th, 2006 (Early morning session)<br />

7h30 – 8h30 : Receptor Signaling : Short communications<br />

7h30 – 7h40 : Jan. S. Jepsen (Danish Cancer Society, Copenhagen, Denmark ) :<br />

Protein Kinase C alpha as a potential target in the treatment of acquired antiestrogen<br />

resistance of human breast cancer.<br />

7h40 – 7h50 : Raymond R. Mattingly (Department of Pharmacology <strong>and</strong> Karmanos Cancer<br />

Institute, Wayne State University, Detroit, Michigan, U.S.A.)<br />

Increased EGF Receptor expression <strong>and</strong> activity is induced by deregulated N-Ras <strong>and</strong> may<br />

provide a therapeutic target in NF1 neurofibrosarcoma<br />

7h50 – 8h00 : Shyamala Maheswaran (Department of Surgical Oncology, Massashusetts<br />

General Hospital, Boston, MA , USA) :<br />

Loss of the Antiproliferative Gene BTG2 in Estrogen Receptor Positive Breast Carcinoma is<br />

Associated with Tumor Grade <strong>and</strong> Overexpression of Cyclin D1 Protein<br />

8h00 – 8h10 : Xiao C. Li (Division of Hypertension <strong>and</strong> Vascular Research, Henry Ford<br />

Hospital, Detroit, MI 48202, USA ) :<br />

Cross-talk between angiotensin II <strong>and</strong> glucagon receptor <strong>signaling</strong> mediates activation of<br />

mitogen-activated protein kinases ERK 1/2 in rat glomerular mesangial cells.<br />

8h10 – 8h20 : Metoda Lipnik-Stangelj (Department of Pharmacology <strong>and</strong> Experimental<br />

Toxicology, Faculty of Medicine, University of Ljubljana, Slovenia) :<br />

Multiple role of histamine H1 receptor-PKC-MAPK signalling pathway in histaminestimulated<br />

nerve growth factor secretion from glial cells<br />

8h20 – 8h30 : Ying E. Zhang (Laboratory of Cellular <strong>and</strong> Molecular Biology, Center for<br />

Cancer Research, National Cancer Institute, National Institutes of Health,<br />

Bethesda, Maryl<strong>and</strong>, USA) :<br />

Ubiquitin ligase Smurf1 controls osteoblast activity <strong>and</strong> bone homeostasis by targeting<br />

MEKK2-JNK pathway<br />

Thursday January 26th, 2006 (Morning session)<br />

8h30 - 10h30: Receptor <strong>signaling</strong><br />

8h30 – 9h00 : Walter Birchmeier (Max-Delbruck-Center for Molecular Medicine, Berlin,<br />

Germany):<br />

The role of Met-Gab1 Signalling in vivo.<br />

9h00 – 9h30 : Ulf R. Rapp (Institut fuer Medizinische Strahlenkunde und Zellforschung<br />

(MSZ), Wuerzburg, Germany):<br />

Role of Prohibtin <strong>and</strong> E-cadherin in Raf mediated oncogenesis<br />

9h30 – 10h00 : Johannes L. Bos (Dept of Physiological Chemistry, Utrecht, The<br />

Netherl<strong>and</strong>s):<br />

Epac <strong>and</strong> Rap1 in the control of cell adhesion<br />

10h00 – 10h10 : Jean-Paul Borg (Molecular Pharmacology, Marseille Cancer Institute,<br />

UMR599 Inserm-Institut Paoli-Calmettes, Marseille, France) :<br />

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