Visit our Expo - Redox and Inflammation signaling 2012

Jespsen JS, Sorensen MD and Wengel J. Locked Nucleic Acid: a potent nucleic acid
analogue in therapeutics and biotechnology. Oligonucleotides. 2004 14(2): 130-146.
Vollmer J, Jepsen JS, Uhlmann E, Schetter C, Jurk M, Wader T, Wullner M and Krieg AM.
Modulation of antisense or CpG oligodeoxynucleotide-mediated immune stimulation by
locked nucleic acid (LNA). Oligonucleotides. 2004 14(1):23-32.
Jepsen JS and Wengel J. LNA-Antisense rivals siRNA for gene silencing.
Current Opinion in Drug Discovery and Development. 2004 7(2):188-194.
Jepsen JS. Locked nucleic acid (lna) as a therapeutic tool to knock down gene expression.
Encyclopedia of medical genomics and proteomics. Accepted.
Jepsen JS and Kauppinen S. Locked nucleic acid (lna) as a tool in biotechnology research
and diagnostics. Encyclopedia of medical genomics and proteomics. Accepted.
Stein CA, Dias N, Benimetskaya L, Jepsen JS, Lai J and Raffo A. LY900003 (Isis 3521) and
G3139 (Genasense; Oblimersen)- Phosphorothioate Antisense Oligonucleotides With
Pleiotropic Mechanisms of Action. Nucleic Acid Therapeutics in Cancer (2004), pp. 177-198.
Edited by Gerwirtz, A., Humana Press (ISBN: 1-58829-258-4).
Hrdlicka, P.J., Jepsen, J.S., Nielsen, C and Wengel, J.: Synthesis and biological evaluation of
conformationally restricted and nucleobase-modified analogs of the anticancer compound 3'-
C-ethynylcytidine (ECyd). Nucleosides Nucleotides Nucleic Acids. 2005 24(5-7): 397-400.
Hrdlicka PJ, Jepsen JS, Nielsen C and Wengel J. Synthesis and biological evaluation of
nucleobase-modified analogs of the anticancer compounds 3’-C-ethynyluridine (EUrd) and
3’-C-ethynylcytidine (ECyd).
Bioorganic & Medicinal Chemistry. 2005 13(4): 1249-1260
Hrdlicka PJ, Andersen NK, Jepsen JS, Hansen FG, Haselmann KF, Nielsen C and Wengel J.
Synthesis and biological evaluation of branched and conformationally restricted analogs of
the anticancer compounds 3’-C-ethynyluridine (EUrd) and 3’-C-ethynylcytidine (ECyd).
Bioorganic & Medicinal Chemistry. 2005 13(7): 2597-2621
Kragelund BB, Poulsen K, Andersen KV, Baldursson T, Kroll JB, Neergard TB, Jepsen J,
Roepstorff P, Kristiansen K, Poulsen FM and Knudsen J. Conserved residues and their role in
the structure, function, and stability of acyl-coenzyme A binding protein. Biochemistry. 1999
Feb 23; 38(8):2386-94.
Jepsen JS Locked nucleic acid (LNA) as cancer-therapeutic agent. Dan Med Bull 2004
51:139.
- 55 -