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Cancer Immune Therapy Edited by G. Stuhler and P. Walden ...

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242 11 Hybrid Cell Vaccination for <strong>Cancer</strong> <strong>Immune</strong> <strong>Therapy</strong><br />

Circulating Melan-A/Mart-1 specific cytolytic<br />

T lymphocyte precursors in<br />

HLA-A2 + melanoma patients have a<br />

memory phenotype. Int J <strong>Cancer</strong> 1998;<br />

78: 699±706.<br />

13 Romero P, Dunbar PR,Valmori D,<br />

Pittet M, Ogg GS, Rimoldi D,<br />

Chen JL, Lienard D, Cerottini JC,<br />

Cerundolo V. Ex vivo staining of metastatic<br />

lymph nodes <strong>by</strong> class I major histocompatibility<br />

complex tetramers reveals<br />

high numbers of antigen-experienced<br />

tumor-specific cytolytic T lymphocytes.<br />

J Exp Med 1998; 188: 1641±<br />

50.<br />

14 Romero P, Gervois N, Schneider J,<br />

Escobar P,Valmori D, Pannetier C,<br />

Steinle A,Wolfel T, Lienard D, Brichard<br />

V, van Pel A, Jotereau F, Cerottini<br />

JC. Cytolytic T lymphocyte recognition<br />

of the immunodominant<br />

HLA-A*0201-restricted Melan-A/MART-<br />

1 antigenic peptide in melanoma. JImmunol<br />

1997; 159: 2366±74.<br />

15 Valmori D, Lienard D,Wa<strong>and</strong>ers G,<br />

Rimoldi D, Cerottini JC, Romero P.<br />

Analysis of MAGE-3-specific cytolytic T<br />

lymphocytes in human leukocyte antigen-A2<br />

melanoma patients. <strong>Cancer</strong> Res<br />

1997; 57: 735±41.<br />

16 Zarour H, De Smet C, Lehmann F,<br />

March<strong>and</strong> M, Lethe B, Romero P,<br />

Boon T, Renauld JC. The majority of<br />

autologous cytolytic T-lymphocyte<br />

clones derived from peripheral blood<br />

lymphocytes of a melanoma patient recognize<br />

an antigenic peptide derived<br />

from gene Pmel17/gp100. J Invest Dermatol<br />

1996; 107: 63±7.<br />

17 Romero P. Cytolytic T lymphocyte responses<br />

of cancer patients to tumor-associated<br />

antigens. Springer Semin Immunopathol<br />

1996; 18: 185±98.<br />

18 Gnjatic S, Nagata Y, Jager E, Stockert<br />

E, Shankara S, Roberts BL, Mazzara<br />

GP, Lee SY, Dunbar PR, Dupont<br />

B, Cerundolo V, Ritter G, Chen YT,<br />

Knuth A, Old LJ. Strategy for monitoring<br />

T cell responses to NY-ESO-1 in patients<br />

with any HLA class I allele. Proc<br />

Natl Acad Sci USA 2000; 97: 10917±22.<br />

19 Jager E, Nagata Y, Gnjatic S,Wada H,<br />

Stockert E, Karbach J, Dunbar PR,<br />

Lee SY, Jungbluth A, Jager D,<br />

Ar<strong>and</strong> M, Ritter G, Cerundolo V,<br />

Dupont B, Chen YT, Old LJ, Knuth A.<br />

Monitoring CD8 T cell responses to NY-<br />

ESO-1: correlation of humoral <strong>and</strong> cellular<br />

immune responses. Proc Natl<br />

Acad Sci USA 2000; 97: 4760±5.<br />

20 Romero P, Dunbar PR,Valmori D,<br />

Pittet M, Ogg GS, Rimoldi D,<br />

Chen JL, Lienard D, Cerottini JC,<br />

Cerundolo V. Ex vivo staining of metastatic<br />

lymph nodes <strong>by</strong> class I major histocompatibility<br />

complex tetramers reveals<br />

high numbers of antigen-experienced<br />

tumor-specific cytolytic T lymphocytes.<br />

J Exp Med 1998; 188: 1641±<br />

50.<br />

21 Ogg GS, Rod Dunbar P, Romero P,<br />

Chen JL, Cerundolo V. High frequency<br />

of skin-homing melanocyte-specific<br />

cytotoxic T lymphocytes in autoimmune<br />

vitiligo. J Exp Med 1998; 188:<br />

1203±8.<br />

22 Anichini A, Molla A, Mortarini R,<br />

Tragni G, Bersani I, Di Nicola M,<br />

Gianni AM, Pilotti S, Dunbar R,<br />

Cerundolo V, Parmiani G. An exp<strong>and</strong>ed<br />

peripheral T cell population to a<br />

cytotoxic T lymphocyte (CTL)-defined,<br />

melanocyte-specific antigen in metastatic<br />

melanoma patients impacts on<br />

generation of peptide-specific CTLs but<br />

does not overcome tumor escape from<br />

immune surveillance in metastatic lesions.<br />

J Exp Med 1999; 190: 651±67.<br />

23 Valmori D, Pittet MJ,Vonarbourg C,<br />

Rimoldi D, Lienard D, Speiser D,<br />

Dunbar R, Cerundolo V, Cerottini<br />

JC, Romero P. Analysis of the cytolytic<br />

T lymphocyte response of melanoma<br />

patients to the naturally HLA-<br />

A*0201-associated tyrosinase peptide<br />

368±376. <strong>Cancer</strong> Res 1999; 59: 4050±5.<br />

24 Schuler-Thurner B, Dieckmann D,<br />

Keikavoussi P, Bender A, Maczek C,<br />

Jonuleit H, Roder C, Haendle I,<br />

Leisgang W, Dunbar R, Cerundolo<br />

V, von Den Driesch P, Knop J,<br />

Brocker EB, Enk A, Kampgen E,<br />

Schuler G. Mage-3 <strong>and</strong> influenza-matrix<br />

peptide-specific cytotoxic T cells are<br />

inducible in terminal stage HLA-A2.1 +<br />

melanoma patients <strong>by</strong> mature monocyte-derived<br />

dendritic cells. J Immunol<br />

2000; 165: 3492±6.

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