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Cancer Immune Therapy Edited by G. Stuhler and P. Walden ...

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Bacterial CpG-DNA activates dendritic<br />

cells in vivo: T helper cell-independent<br />

cytotoxic Tcell responses to soluble proteins.<br />

Eur J Immunol 2000; 30: 3591±<br />

3597.<br />

118 Vabulas, R. M., Pircher, H., Lipford,<br />

G. B., Hacker, H. <strong>and</strong> Wagner, H.<br />

CpG-DNA activates in vivo T cell epitope<br />

presenting dendritic cells to trigger<br />

protective antiviral cytotoxic T cell responses.<br />

J Immunol 2000; 164: 2372±<br />

2378.<br />

119 Chu, R. S.,Targoni, O. S., Krieg, A. M.,<br />

Lehmann, P. V. <strong>and</strong> Harding, C. V.<br />

CpG oligodeoxynucleotides act as adjuvants<br />

that switch on T helper 1 (Th1) immunity.<br />

J Exp Med 1997; 186: 1623±<br />

1631.<br />

120 Roman, M., Martin-Orozco, E.,<br />

Goodman, J. S., et al. Immunostimulatory<br />

DNA sequences function as<br />

T helper-1-promoting adjuvants [see<br />

Comments]. Nat Med 1997; 3: 849±854.<br />

121 Wild, J., Grus<strong>by</strong>, M. J., Schirmbeck, R.<br />

<strong>and</strong> Reimann, J. Priming MHC-I-restricted<br />

cytotoxic T lymphocyte responses<br />

to exogenous hepatitis B surface<br />

antigen is CD4 + T cell dependent.<br />

J Immunol 1999; 163: 1880±1887.<br />

122 Davis, H. L.,Weeratna, R., Waldschmidt,<br />

T. J., et al. CpG DNA is a potent<br />

enhancer of specific immunity in<br />

mice immunized with recombinant hepatitis<br />

B surface antigen [published erratum<br />

appears in J Immunol 1999;<br />

162(5): 3103]. J Immunol 1998; 160:<br />

870±876.<br />

123 Weiner, G. J., Liu, H. M., Wooldridge,<br />

J. E., Dahle, C. E. <strong>and</strong><br />

Krieg, A. M. Immunostimulatory<br />

oligodeoxynucleotides containing the<br />

CpG motif are effective as immune adjuvants<br />

in tumor antigen immunization.<br />

Proc Natl Acad Sci USA 1997; 94:<br />

10833±10837.<br />

124 Sun, S., Kishimoto, H. <strong>and</strong> Sprent, J.<br />

DNA as an adjuvant: capacity of insect<br />

DNA <strong>and</strong> synthetic oligodeoxynucleotides<br />

to augment T cell responses to<br />

specific antigen. J Exp Med 1998; 187:<br />

1145±1150.<br />

125 Kim, S. K., Ragupathi, G., Musselli, C.,<br />

et al. Comparison of the effect of different<br />

immunological adjuvants on the<br />

References<br />

antibody <strong>and</strong> T-cell response to immunization<br />

with MUC1±KLH <strong>and</strong> GD3±KLH<br />

conjugate cancer vaccines. Vaccine 1999;<br />

18: 597±603.<br />

126 Liu, H. M., Newbrough, S. E.,<br />

Bhatia, S. K., et al. Immunostimulatory<br />

CpG oligodeoxynucleotides enhance<br />

the immune response to vaccine<br />

strategies involving granulocyte-macrophage<br />

colony-stimulating factor. Blood<br />

1998; 92: 3730±3736.<br />

127 Davila, E. <strong>and</strong> Celis, E. Repeated administration<br />

of cytosine-phosphorothiolated<br />

guanine-containing oligonucleotides<br />

together with peptide/protein immunization<br />

results in enhanced CTL<br />

responses with anti-tumor activity. JImmunol<br />

2000; 165: 539±547.<br />

128 Egeter, O., Mocikat, R., Ghoreschi, K.,<br />

Dieckmann, A. <strong>and</strong> Rocken, M. Eradication<br />

of disseminated lymphomas with<br />

CpG-DNA activated T helper type 1 cells<br />

from nontransgenic mice. <strong>Cancer</strong> Res<br />

2000; 60: 1515±1520.<br />

129 Brunner, C., Seiderer, J., Schlamp, A.,<br />

et al. Enhanced dendritic cell maturation<br />

<strong>by</strong> TNF-a or cytidine-phosphate-guanosine<br />

DNA drives Tcell activation in vitro<br />

<strong>and</strong> therapeutic anti-tumor immune responses<br />

in vivo. J Immunol 2000; 165:<br />

6278±6286.<br />

130 Wooldridge, J. E., Ballas, Z.,<br />

Krieg, A. M. <strong>and</strong> Weiner, G. J. Immunostimulatory<br />

oligodeoxynucleotides<br />

containing CpG motifs enhance the<br />

efficacy of monoclonal antibody therapy<br />

of lymphoma. Blood 1997; 89: 2994±<br />

2998.<br />

131 Warren, T. L., Dahle, C. E. <strong>and</strong> Weiner,<br />

G. J. CpG oligodeoxynucleotides<br />

enhance monoclonal antibody therapy<br />

of a murine lymphoma. Clin Lymphoma<br />

2000; 1: 57±61.<br />

132 Jahrsdorfer, B., Hartmann, G., Racila,<br />

E., et al. CpG DNA increases primary<br />

malignant B cell expression of<br />

costimulatory molecules <strong>and</strong> target<br />

antigens. J Leuk Biol 2001; 69: 81±88.<br />

133 Decker, T., Schneller, F., Sparwasser,<br />

T., et al. Immunostimulatory<br />

CpG-oligonucleotides cause proliferation,<br />

cytokine production, <strong>and</strong> an immunogenic<br />

phenotype in chronic lym-<br />

285

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