Interior 2_2006.qxd - Oftalmologia.ro

ABSTRACT
OFTALMOLOGIA 2 - 2006
PURPOSE
The main objective of this study was to identify the prevalence of ocular manifestations in rheumatic
patients admitted in a specialized clinic.
METHODS
Information regarding rheumatic and ocular diseases was extracted from medical records system
available in "Dr. I. Cantacuzino" Clinical Hospital from Bucharest. The prevalence of ocular involvement
reported passively by rheumatologists (retrospective descriptive study of 375 different cases of rheumatic
patients) was compared with the literature data.
RESULTS
There were 45 cases of ocular manifestations. Keratoconjunctivitis sicca was noted in 16 patients with
rheumatoid arthritis, two patients with systemic lupus erythematosus and one patient with scleroderma.
Anterior uveitis was found in seven patients with ankylosing spondylitis, one patient with reactive arthritis,
two patients with psoriatic arthritis and one patient with LES. Conjunctivitis was present in two patients with
reactive arthritis. In LES ocular involvement also included four cases of retinal vasculitis. Complications clearly
related to steroid therapy were nine cases of cataracts. One case with typical "bull's eye" maculopathy due
to Hydroxychloroquine treatment was detected.
CONCLUSIONS
The main conclusion of our study is that the rheumatic patients need to be referred to an ophthalmologist
for the diagnosis and the optimal treatment of ocular involvement.
KEYWORDS:
• Rheumatic diseases,
• Ocular manifestation .
INTRODUCERE
Afectiunile reumatismale reprezinta un ansamblu de boli mediate imunologic avand o multitudine de
manifestari care intereseaza diferite organe si sisteme. Diagnosticarea acestora se bazeaza pe indeplinirea
unor criterii stabilite de Colegiul American de Reumatologie (ACR)(1,2). Multe din bolile reumatismale sunt
asociate cu manifestari oftalmologice cum ar fi conjunctivite, KCS, uveite, afectare vasculara retiniana sau
leziuni neuro-oftalmologice. Astfel, in RA apar mai frecvent KCS, episclerite si sclerite (3,4), in spondilartrite
seronegative se intalnesc adesea uveite anterioare (5,6), in timp ce leziunile vasculare retiniene si cele neurooftalmologice
apar frecvent in LES (7,8) sau in vasculite sistemice (9,10).
SCOPUL STUDIULUI
Lucrarea de fata si-a propus determinarea incidentei si a tipului de afectare oftalmologica in randul pacientilor
cu boli reumatologice internati intr-o clinica de specialitate precum si identificarea reactiilor adverse
oculare asociate cu terapia administrata, rezultatele obtinute fiind comparate cu cele publicate in literatura de
specialitate.
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