PDF (5 MB) - Jurnalul de Chirurgie
PDF (5 MB) - Jurnalul de Chirurgie
PDF (5 MB) - Jurnalul de Chirurgie
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CAZURI CLINICE 397<strong>Jurnalul</strong> <strong>de</strong> <strong>Chirurgie</strong> (Iaşi), 2012, Vol. 8, Nr. 3EFECTELE MEGALIPOSUCŢIEI CU ULTRASUNETEASUPRA INDICELUI DE MASĂ CORPORALĂ ŞICONCENTRAŢIEI SERICE DE LEPTINĂ LA FEMEILEOBEZE – PREZENTARE DE CAZLaura Maria Curic 1, , F. Bassetto 2 , Carmen Vulpoi 31) Clinica <strong>de</strong> <strong>Chirurgie</strong> Plastică şi ReconstructivăUniversitatea <strong>de</strong> Medicină şi Farmacie „Gr.T. Popa” Iaşi2) Clinica <strong>de</strong> <strong>Chirurgie</strong> Plastică şi ReconstructivăUniversitatea <strong>de</strong> Medicină şi Farmacie Padova3) Clinica <strong>de</strong> EndocrinologieUniversitatea <strong>de</strong> Medicină şi Farmacie „Gr.T. Popa” IaşiTHE EFFECTS OF ULTRASOUND-ASSISTED MEGALIPOSUCTION ON BODY MASSINDEX AND SERIC LEPTIN LEVEL IN OBESE WOMEN - CASE REPORT (Abstract):INTRODUCTION: Numerous studies in the literature shows that liposuction has a functional role(removal of large quantities of fat would lead to an increase lipase activity, leading to a continuedreduction in body weight, linked to an inhibition of the hunger center through a feedbackmechanism). Nowadays, liposuction is performed not only for aesthetic reasons, but also intherapy to improve quality of life of obese patients. CASE REPORT: We exemplify the effects ofthe surgical removal of subcutaneous adipose tissue by ultrasound-assisted megaliposuction(UAM) on body mass in<strong>de</strong>x (BMI) and seric leptin level in a 53 years old premenopausal obesewomen. UAM reduced both parameters in the first six months after surgery, without furtherimportant changes in the following six months. Leptin levels transiently increased after UAM andthen <strong>de</strong>clined according to fat mass reduction. Leptin levels were directly associated with BMI,except postoperative inflammatory phase. Only one minor complication was noted, a burn whichwas solved favorably. CONCLUSIONS: The results are consistent with existing data in literatureand in addition is a response to the dilemmas and conflicting statements about this issue.KEY WORDS: OBESITY; ULTRASOUND-ASSISTED-MEGALIPOPLASTY; LEPTIN;BODY MASS INDEXSHORT TITLE: Ultrasound assisted megalipoplastyMegaliposucţie cu ultrasuneteHOW TO CITE: Curic ML, Bassetto F, Vulpoi C. [The effects of ultrasound-assisted megaliposuction on body mass in<strong>de</strong>xand seric leptin level in obese women- case report]. <strong>Jurnalul</strong> <strong>de</strong> chirurgie (Iaşi). 2012; 8(4): 397-402.INTRODUCEREObezitatea este o afecţiune complexă,multifactorială, o condiţie medicală gravă carezultat al unui câştig persistent în greutatepe seama ţesutului adipos (aportul <strong>de</strong> energie<strong>de</strong>păşind consumul). În ultimele <strong>de</strong>ca<strong>de</strong> ea a<strong>de</strong>venit una din cele mai frecvente boli <strong>de</strong>nutriţie din lume, având amploarea uneipan<strong>de</strong>mii, conform raportului OMS 2011,fiind consi<strong>de</strong>rată boala secolului XXI [1].Chirurgia bariatrică este o metodă eficientă<strong>de</strong> tratament a obezităţii morbi<strong>de</strong> şireprezintă opţiunea terapeutică cea maia<strong>de</strong>cvată pentru aceşti pacienţi [2].Numeroase studii din literatură,<strong>de</strong>monstrează că liposucţia clasică şivariantele sale mo<strong>de</strong>rne au şi un rolfuncţional (extragerea unei importantecantităţi <strong>de</strong> ţesut adipos ar duce laaccentuarea activităţii lipazei, ducând printr-Received date: 28.05.2012Accepted date: 10.08.2012Adresa <strong>de</strong> corespon<strong>de</strong>nţă: Dr. Laura Maria CuricDoctorand Universitatea <strong>de</strong> Medicină şi Farmacie „Gr T Popa” IaşiClinica <strong>de</strong> <strong>Chirurgie</strong> Plastică şi ReconstructivăStr. Pictorului, nr. 3, 700321, Iaşi, Romaniae-mail: lauracuric2004@yahoo.com.