Manual Intensivmedizin - Levofloxacin

Manual Intensivmedizin 19
Zienam = Imipenem
Pckg Pckg 250/500mg
D 3mal 500-1000mg
Dosisreduktion bei NI 100/75/50
Zovirax = Aciclovir
Pckg Fl. 250/500mg, Tab. 200/400/800mg
D Zoster: 3mal 5-10mg/kg, 70kg: 3mal 500mg i.v.
Herpesenzephalitis: 3mal 10mg/kg, 70kg: 3mal 750mg i.v.
Dosisreduktion bei NI 100/50/15
Zyvoxid = Linezolid
Pckg Infusionsbeutel (600mg), Filmtabletten (600mg), Granulat zur Anfertigung einer Suspension
D 600mg 1-0-1 i.v. oder p.o., bei i.v.-Gabe Laufzeit 30-120 min
Keine Dosisreduktion bei Niereninsuffizienz
Aktuelle Resistenzstatitistik der I2 aus dem Jahr 2007
Enterokokken
Koagulaseneg.
Staphylokokken
S. aureus
Escherichia
coli
Klebsiella
spp.
Pseudom.
aeruginosa
Proteus
mirabilis
n= 52 60 54 55 22 7 7
Ampicillin 25% 85% 80% 36% 100% 100% 43%
Mezlozillin 25% 85% 80% 36% 100% 29% 43%
Piperacillin 25% 85% 80% 36% 100% 0% 43%
Amoxicillin/
Clavulansäure
Piperacillin/
Tazobactam
23% 70% 35% 13% 23% 100% 0%
23% 70% 35% 4% 0% 0% 0%
Cefuroxim-Axetil 100% 70% 33% 13% 23% 100% 0%
Cefotiam 100% 70% 33% 13% 23% 100% 0%
Cefotaxim 100% 70% 33% 5% 5% 100% 0%
Imipenem 23% 70% 33% 0% 0% 0% 0%
Meropenem 23% 70% 33% 0% 0% 0% 0%
Gentamicin 100% 45% 7% 2% 5% 0% 14%
Vancomycin 2% 0% 0% 100% 100% 100% 100%
Levofloxacin 50% 62% 37% 15% 9% 29% 29%
Erythromycin 35% 65% 44% 100% 100% 100% 100%
Clindamycin 100% 65% 44% 100% 100% 100% 100%
Cotrimoxazol 100% 47% 6% 24% 18% 100% 43%
Tetrazyklin 69% 10% 4% 25% 27% 100% 100%