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toxicological profile for malathion - Agency for Toxic Substances and ...

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MALATHION 1<br />

1. PUBLIC HEALTH STATEMENT<br />

This public health statement tells you about <strong>malathion</strong> <strong>and</strong> the effects of exposure.<br />

The Environmental Protection <strong>Agency</strong> (EPA) identifies the most serious hazardous waste sites in<br />

the nation. These sites make up the National Priorities List (NPL) <strong>and</strong> are the sites targeted <strong>for</strong><br />

long-term federal cleanup activities. Malathion has been found in at least 21 of the 1,623 current<br />

or <strong>for</strong>mer NPL sites. However, the total number of NPL sites evaluated <strong>for</strong> this substance is not<br />

known. As more sites are evaluated, the sites at which <strong>malathion</strong> is found may increase. This<br />

in<strong>for</strong>mation is important because exposure to this substance may harm you <strong>and</strong> because these<br />

sites may be sources of exposure.<br />

When a substance is released from a large area, such as an industrial plant, or from a container,<br />

such as a drum or bottle, it enters the environment. This release does not always lead to<br />

exposure. You are exposed to a substance only when you come in contact with it. You may be<br />

exposed by breathing, eating, or drinking the substance, or by skin contact.<br />

If you are exposed to <strong>malathion</strong>, many factors determine whether you'll be harmed. These<br />

factors include the dose (how much), the duration (how long), <strong>and</strong> how you come in contact with<br />

it/them. You must also consider the other chemicals you're exposed to <strong>and</strong> your age, sex, diet,<br />

family traits, lifestyle, <strong>and</strong> state of health.<br />

1.1 WHAT IS MALATHION?<br />

Malathion is a pesticide that is used to kill insects on agricultural crops, on stored products, on<br />

golf courses, in home gardens, <strong>and</strong> in outdoor sites where trees <strong>and</strong> shrubs are grown at home; it<br />

is also used to kill mosquitoes <strong>and</strong> Mediterranean fruit flies (medflies) in large outdoor areas.<br />

Additionally, <strong>malathion</strong> is used to kill fleas on pets <strong>and</strong> to treat head lice on humans. It is<br />

usually sprayed on crops or sprayed from an airplane over wide l<strong>and</strong> areas, especially in the<br />

states of Cali<strong>for</strong>nia <strong>and</strong> Florida. Malathion comes in two <strong>for</strong>ms: a pure <strong>for</strong>m of a colorless liquid<br />

<strong>and</strong> a technical-grade solution (brownish-yellow liquid), which contains <strong>malathion</strong> (greater than

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