toxicological profile for malathion - Agency for Toxic Substances and ...

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MALATHION C-3 APPENDIX C MFO mixed function oxidase mg milligram mL milliliter mm millimeter mmHg millimeters of mercury mmol millimole mppcf millions of particles per cubic foot MRL Minimal Risk Level MS mass spectrometry NAAQS National Ambient Air Quality Standard NAS National Academy of Science NATICH National Air Toxics Information Clearinghouse NATO North Atlantic Treaty Organization NCE normochromatic erythrocytes NCEH National Center for Environmental Health NCI National Cancer Institute ND not detected NFPA National Fire Protection Association ng nanogram NIEHS National Institute of Environmental Health Sciences NIOSH National Institute for Occupational Safety and Health NIOSHTIC NIOSH's Computerized Information Retrieval System NLM National Library of Medicine nm nanometer NHANES National Health and Nutrition Examination Survey nmol nanomole NOAEL no-observed-adverse-effect level NOES National Occupational Exposure Survey NOHS National Occupational Hazard Survey NPD nitrogen phosphorus detection NPDES National Pollutant Discharge Elimination System NPL National Priorities List NR not reported NRC National Research Council NS not specified NSPS New Source Performance Standards NTIS National Technical Information Service NTP National Toxicology Program ODW Office of Drinking Water, EPA OERR Office of Emergency and Remedial Response, EPA OHM/TADS Oil and Hazardous Materials/Technical Assistance Data System OPP Office of Pesticide Programs, EPA OPPTS Office of Prevention, Pesticides and Toxic Substances, EPA OPPT Office of Pollution Prevention and Toxics, EPA OR odds ratio OSHA Occupational Safety and Health Administration OSW Office of Solid Waste, EPA OW Office of Water OWRS Office of Water Regulations and Standards, EPA PAH polycyclic aromatic hydrocarbon PBPD physiologically based pharmacodynamic
MALATHION C-4 APPENDIX C PBPK physiologically based pharmacokinetic PCE polychromatic erythrocytes PEL permissible exposure limit pg picogram PHS Public Health Service PID photo ionization detector pmol picomole PMR proportionate mortality ratio ppb parts per billion ppm parts per million ppt parts per trillion PSNS pretreatment standards for new sources RBC red blood cell REL recommended exposure level/limit RfC reference concentration RfD reference dose RNA ribonucleic acid RTECS Registry of Toxic Effects of Chemical Substances RQ reportable quantity SARA Superfund Amendments and Reauthorization Act SCE sister chromatid exchange SGOT serum glutamic oxaloacetic transaminase SGPT serum glutamic pyruvic transaminase SIC standard industrial classification SIM selected ion monitoring SMCL secondary maximum contaminant level SMR standardized mortality ratio SNARL suggested no adverse response level SPEGL Short-Term Public Emergency Guidance Level STEL short term exposure limit STORET Storage and Retrieval TD50 toxic dose, 50% specific toxic effect TLV threshold limit value TOC total organic carbon TPQ threshold planning quantity TRI Toxics Release Inventory TSCA Toxic Substances Control Act TWA time-weighted average UF uncertainty factor U.S. United States USDA United States Department of Agriculture USGS United States Geological Survey VOC volatile organic compound WBC white blood cell WHO World Health Organization
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TOXICOLOGICAL PROFILE FOR MALATHION
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MALATHION iii UPDATE STATEMENT A To
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MALATHION viii Managing Hazardous M
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MALATHION xi PEER REVIEW A peer rev
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MALATHION xiv 3.2.3.2 Systemic Effe
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MALATHION xvii LIST OF FIGURES 3-1.
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MALATHION 1 1. PUBLIC HEALTH STATEM
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MALATHION 11 1. PUBLIC HEALTH STATE
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MALATHION 14 2. RELEVANCE TO PUBLIC
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MALATHION 24 3. HEALTH EFFECTS oral
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MALATHION 26 3. HEALTH EFFECTS sing
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≤
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MALATHION 30 3. HEALTH EFFECTS Resp
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MALATHION 32 3. HEALTH EFFECTS Rena
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MALATHION 34 3. HEALTH EFFECTS Stud
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MALATHION 36 3. HEALTH EFFECTS Fran
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MALATHION 38 3. HEALTH EFFECTS more
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MALATHION 40 3. HEALTH EFFECTS the
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a Key to figure 1 2 3 4 5 6 Species
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a Key to figure 15 16 17 18 Species
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a Key to figure 24 25 26 27 28 29 S
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a Key to figure 40 41 42 43 44 45 S
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a Key to figure 55 56 57 58 59 60 S
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a Key to figure 67 68 69 70 Species
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a Key to figure 83 84 85 86 87 88 8
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a Key to figure 91 Species (Strain)
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a Key to figure 93 94 Species (Stra
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≤
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≤
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MALATHION 64 3.2.2.2 Systemic Effec
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MALATHION 66 3. HEALTH EFFECTS 1965
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MALATHION 68 3. HEALTH EFFECTS Hepa
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MALATHION 70 3. HEALTH EFFECTS appr
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MALATHION 72 3. HEALTH EFFECTS an u
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MALATHION 74 3. HEALTH EFFECTS Meta
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MALATHION 76 3. HEALTH EFFECTS clas
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MALATHION 78 3. HEALTH EFFECTS was
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MALATHION 80 3. HEALTH EFFECTS appr
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MALATHION 82 3. HEALTH EFFECTS Clin
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MALATHION 84 3. HEALTH EFFECTS mala
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MALATHION 86 3. HEALTH EFFECTS Tera
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MALATHION 88 3. HEALTH EFFECTS for
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MALATHION 90 3. HEALTH EFFECTS sugg
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Species (Strain) Systemic Exposure/
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MALATHION 94 3. HEALTH EFFECTS Endo
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MALATHION 96 3. HEALTH EFFECTS Othe
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MALATHION 98 3. HEALTH EFFECTS derm
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MALATHION 100 3. HEALTH EFFECTS al.
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MALATHION 102 3. HEALTH EFFECTS of
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MALATHION 104 3. HEALTH EFFECTS per
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MALATHION 106 3.4.1.1 Inhalation Ex
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MALATHION 108 3. HEALTH EFFECTS was
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MALATHION 110 3. HEALTH EFFECTS fir
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MALATHION 112 3.4.2.3 Dermal Exposu
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MALATHION 114 3. HEALTH EFFECTS neu
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MALATHION 116 3. HEALTH EFFECTS aci
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MALATHION 118 3.4.4.1 Inhalation Ex
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MALATHION 120 3. HEALTH EFFECTS agr
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MALATHION 122 V E N O U S BLOOD 3.
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MALATHION 124 3. HEALTH EFFECTS Tab
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MALATHION 126 3. HEALTH EFFECTS mus
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MALATHION 128 3.5.2 Mechanisms of T
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MALATHION 130 3. HEALTH EFFECTS pla
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MALATHION 132 3. HEALTH EFFECTS In
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MALATHION 134 3. HEALTH EFFECTS Ove
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MALATHION 136 3. HEALTH EFFECTS are
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MALATHION 138 3. HEALTH EFFECTS whe
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MALATHION 140 3. HEALTH EFFECTS the
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MALATHION 142 3. HEALTH EFFECTS org
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MALATHION 144 3. HEALTH EFFECTS The
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MALATHION 146 3. HEALTH EFFECTS pla
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MALATHION 148 3. HEALTH EFFECTS org
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MALATHION 150 3. HEALTH EFFECTS stu
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MALATHION 152 3. HEALTH EFFECTS Par
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MALATHION 154 3. HEALTH EFFECTS exp
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MALATHION 156 3. HEALTH EFFECTS wer
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MALATHION 158 3. HEALTH EFFECTS who
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MALATHION 160 3. HEALTH EFFECTS Lee
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MALATHION 162 3. HEALTH EFFECTS res
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MALATHION 164 3. HEALTH EFFECTS inf
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MALATHION 166 3. HEALTH EFFECTS med
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MALATHION 168 4. CHEMICAL AND PHYSI
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MALATHION 171 5. PRODUCTION, IMPORT
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MALATHION 173 5. PRODUCTION, IMPORT
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MALATHION 175 6.1 OVERVIEW 6. POTEN
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MALATHION 177 6. POTENTIAL FOR HUMA
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MALATHION 187 6.3.2.1 Air 6. POTENT
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MALATHION 216 7. ANALYTICAL METHODS
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MALATHION 224 7.3.1 Identification
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MALATHION 226 8. REGULATIONS AND AD
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MALATHION 238 9. REFERENCES *Agency
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MALATHION 240 9. REFERENCES *Barnes
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MALATHION 242 9. REFERENCES *Brown
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MALATHION 244 9. REFERENCES *Choi P
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MALATHION 246 9. REFERENCES *De Ble
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MALATHION 248 9. REFERENCES Ehrich
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MALATHION 250 9. REFERENCES EPA. 20
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MALATHION 252 9. REFERENCES *Gaines
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Page 277 and 278: MALATHION 258 9. REFERENCES Kimbrou
Page 279 and 280: MALATHION 260 9. REFERENCES *Lechne
Page 281 and 282: MALATHION 262 9. REFERENCES *Mackis
Page 283 and 284: MALATHION 264 9. REFERENCES Mohn G.
Page 285 and 286: MALATHION 266 9. REFERENCES NIOSH.
Page 287 and 288: MALATHION 268 9. REFERENCES *Prabha
Page 289 and 290: MALATHION 270 9. REFERENCES *Roy RR
Page 291 and 292: MALATHION 272 9. REFERENCES *Singar
Page 293 and 294: MALATHION 274 9. REFERENCES *Thongs
Page 295 and 296: MALATHION 276 9. REFERENCES Viccell
Page 297 and 298: MALATHION 278 9. REFERENCES Yess NJ
Page 299 and 300: MALATHION 280 10. GLOSSARY Ceiling
Page 301 and 302: MALATHION 282 10. GLOSSARY Mutagen
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Page 305 and 306: MALATHION A-2 APPENDIX A are not ex
Page 307 and 308: MALATHION A-4 APPENDIX A Was a conv
Page 309 and 310: MALATHION A-6 APPENDIX A Was a conv
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Page 313 and 314: MALATHION A-10 Uncertainty Factors
Page 315 and 316: MALATHION B-2 Interpretation of Min
Page 317 and 318: MALATHION B-4 APPENDIX B (8) NOAEL
Page 319 and 320: 1 2 3 4 12 → → → → → Key
Page 322 and 323: MALATHION C-1 APPENDIX C. ACRONYMS,
Page 326: MALATHION C-5 > greater than $ grea
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