toxicological profile for malathion - Agency for Toxic Substances and ...

a
Key to
figure
7
8
9
10
11
12
13
14
Death
Species
(Strain)
Exposure/
Duration/
Frequency
(Specific Route)
System
Table 3-2 Levels of Significant Exposure to Malathion - Oral
NOAEL
(mg/kg/day)
Less Serious
LOAEL
Serious
(mg/kg/day) (mg/kg/day)
(continued)
Reference
Chemical Form
Mouse once Rodgers et al. 1986
1430 F (LD50)
(C57BL/ 6N) (GO)
Mouse once Talcott et al. 1979a
3200 M (LD50 for recrystallized)
(Swiss) (GO)
Mouse once Talcott et al. 1979a
2600 M (LD50)
(C57B1) (GO)
once Umetsu et al. 1977
3000 (LD50 of 99.3% pure)
(Swiss white) (G)
1850 b Mouse
(LD50 of 95% pure)
Rabbit
(New
Zealand)
Systemic
once
(GO)
1200 M (5 out of 6 died 6 hours after
dosing)
Weeks et al. 1977
Rat once
(Long- Evans) (GO)
Bd Wt 2000 M
Ehrich et al. 1993
Rat
(Wistar)
Rat
(Wistar)
14 d
1x/2d
(G)
2 d
1x/d
(G)
Bd Wt
Bd Wt
10 M
40 M
Krause 1977
Krause et al. 1976