Vol. 60, 1909 - University of North Carolina at Chapel Hill

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72 THE CHARLOTTE MEDICAL JOURNAL casesof "pellagra-sine-pellagra," I havenot case of acute pellagra in a child eleven noticed the peculiar ulceration which forms years of age by the hypodermic injection from time to time on the buccal mucous of four grains of atoxyl, repeated every j membrane on the roof of the mouth and be- fourth day. The drug in no way altered tvveen the last molar teeth on both lower the course of the disease. I doubt very, and upper jaws. The stomatitis of pellagra much whether this arsenic treatment which is usually a simple redness, w!th salivation was successful in the milder European but without definite ulcerated patches. I form of the disease, would affect our very am disposed to question the correctness of severe and rapidly fatal cases. It is interthe diagnosis of these cases, or to cpiestion esting, however, to note in. this connection the correctness of the diagnosis of our cases that the disease as we see it today is very of "pellagra-sine-pellagra," because, in much more attenuated than our first cases both conditions, the symptoms and course three years ago. Three years ago our were practically identical. It is far more cases always died while at the present time likely that the diagnosis of pellagra is cor- the disease is assuming tlie more characterrect, and that the diagnosis of sprue was istic chronic form which is very much made through an imperfect knowledge of milder. It is to be hoped that in these pellagra. I think that if Dr. Harris should cases the arsenic treatment may give usjfsee some of our cases of pellagra, and also some encouragement. some of our cases of "pellagra-sine-pella- After all, we must look to serum therapy^ gra" that he would be disposed to accept for relief. As mentioned above, we hav< our view. It is to be hoped that, with the every reason to expect the early preparatiou| discovery- of a specific organism of pellagra, of a curative serum. 4 we may be able to resort to a definite ag- In concluding this paper, Iwouldlike^' glutination test similar to the Widal test in again to entreat the medical profession in typhoid fever. We have some grounds for North Carolina for their support and co- I thinking that this test will be perfected operation in the study of a disease that bids ' shortly. fair to be second only to tuberculosis in its I The treatment of pellagra has been one of importance. We are already deeply inthe most disappointing in medicine. There debted to many members of this Society for. is no specific, and first one remedy after an- their assistance during the past year, and I other has been extolled, only to be thrust take this opportunity to assure them that aside after the demonstration of its useless- any information or report of cases, or ideas ness. In our experience, from the begin- as to the etiological factors in this disease ! ning, we are able to predict with a fair de- will be highly appreciated. We are ready , gree of certainty, those cases that will re- to" give our time and our means, as far as i cover and those that will succumi) after a we are able, to the study of pellagra, and '\ few weeks, or possibly a few months, of we feel that we will not plead in vain for untold physical and mental suffering. In the assistance of our brother practitioners, the Berliner Klinische Wochenschrift for who should be just as deeply concerned in i February 8th, 1909, there is a notable arti- the outcome of our studies as we are our- : ' cle by Babes, \'asiliu and Gheorghus, in selves. which they advocate the treatment of these . T patients by Introductory. arsenic, , given in three wa.N's, simultaneously. They inject 7 '2 gr. atoxyl Mr. President and Gentlemen: hypodermically, and in addition to this, I desire to express ray high appreciation j | they have rubbed into the patients skin, 75 of the honor conferred upon me bv the in- / gr. of an ointment composed of a 1 to ,50 vitation of the Tri-State Medical Associa- \ arsenious acid preparation, Finally, they tion, ccniveved through their secretarv, to I have the patient take internally, one fiftieth read a paper at its 11th annual session. 1 of a grain of arsenious acid in pill form. This invitation has given me all the more I three times a day. These observers have pleasure to accept, because the meeting was 1 treated sixty five cases of pellegra in this to be held in Charleston, vS. C. mv beloved ! manner with the loss of only six cases. In native city, where I have not lived for a the article referred to above, they report a number of vears, but to which I always - series of fourteen cases, all of which re- return with a sense of coming home,—and .a sponded readily to from one to three treat- for this opportunity I wish to tender my j ments as detailed above, : and have gone for grateful acknowledgment. a number of months with no sign of any I interpret the invitation, however, as a \ recurrence. In all of these ca.ses there was tribute to the work in which I have been ii a marked gam in weight. At the present so long engaged, rather than as any per- \ time, 1 am giving this treatment a trial, but sonal compliment to myself, and I : have, i am not yet prepared ;o report my experi- therefore, regarded it somewhat in the light . \ ence with it. Last summer I treated a of a command that I should select for the i ' I
ORIGINAL COMMUNICATIONS subject of this address the consideration of some branch of medicine relative to this particular line of work. Hut after scanning the wide field of material, which is now included under Sanitary Science, I found so many interesting and profitable subjects for discussion, demanding eciu
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NORTH CAROLINA HISTORY OF HEALTH DI
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lARLOTTK MEDICAL lOURNAL. ^ SANMETT
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THE CHARLOTTE MEDICAL JOURNAL. Chat
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THE BABIES «HC thrive the best dur
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VIII THE CHARLOIVTE MEDICAL JOURNAL
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THK CHARLOTTE MEDICAL JOURNAL. MILK
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THE CHARLOTTE MEDICAL JOURNAL. NEUR
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PHF. CHARLOTTE MEDICAL JOURNAL. Atl
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AKLOTTE MKDICAL JOl'KNAL E^legant P
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THE CHARLOTTE MEDICAL JOURNAL. "We
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^^ THE CHARLOTTE MfiDICAL JOURNAL.
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' \ fth ORIGINAL COMMUNICATIONS.
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ORIGINAL COMMUNICATIONS, 5 trate ul
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ORIGINIAL COMMUNICATIONS. 7 careful
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; THE CHARLOTTE MEDICAL JOURNAL. 9
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ORIGINAL COMMUNICATIONS. 11 tuber i
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ORIGINAI, COMMCNICATIONS lo neum ab
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The chief causative factors of gast
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ORIGINAL COMMUNICATIONS. to adminis
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ease itself. The deportment of the
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ORIGINAL COMMUNICATIOXS, 21 process
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OEIGINAI. COMMUNICATIONS. 23 down t
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ORIGINAL COMMUNICATIOMS. 25 this In
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ORIGINAL OOMJIUXICATION. 27 tro-int
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ORIGIXAL COMMCNICATIONS. 29 the sam
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ORIGINAL COMMUNICATIONS. 31 tioii.
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EDITORIAL. 33 rUai'lriiio Lnai JOli
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EDITORIAL. oD Ham Jones, of High Po
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EDITORIAL. 37 Siler, of the U. S. A
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8. What is the differential diagnos
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Edgar M. Long, Hamilton. Ben F. Roy
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and H. A. Slack. "Infection and Imm
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EDITORIAI,. 45 Dr. Claude N. Smith
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I C. EDITORIAL. Association, the Am
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REVIEW OF SOUTHERN MEDICAL LITERATU
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REVIEW OF SOUTHERN- MEDICAL LITERAT
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Book Notices. The Popes and Science
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ADBVRTISEMENTS.
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INDEX FOR JULY, Table of Contents f
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ABSTRACTS Genielli, who is himself
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ADVERTISEMENTS. St. Luke's Hospital
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ADVERTISEMENTS. a mixture containin
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ADVERTISEMENTS. SOUTHERN MEDICAL SO
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»»< ADVERTISEMENTS. To obtain the
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— ADVERTISEMENTS. XXIX THE PINES,
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A most powerful non-toxic bacterici
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ADVERTISEMENTS. The Sarah Leigh Hos
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ADVERTISEMENTS. Baby needs Mellin's
Page 97 and 98: ADVERTISEMENTS. MALT WIXH REPRESENT
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Page 101 and 102: ADVERTISEMENTS. The State Examining
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Page 105 and 106: ADVERTIESMENTS, r^mmmmmmmmmmm^mmm^m
Page 107 and 108: ADVERTISKEMTS '^he niGKSMITH HOSPIT
Page 109 and 110: VDVERTISEMEXTS ERUPTION^ Inflammati
Page 111 and 112: ADVERTISEMENTS. The Success of List
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Page 115 and 116: ttiiALIH AFFAiRS LIBRARY Charlotte
Page 117 and 118: ADVERTISEMENTS. F>OST -TTPHOI RECON
Page 119 and 120: C ADVERTISEMENTS. BOVININE Reconstr
Page 121 and 122: ADVERTISEMENTS. Successfully Prescr
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Page 125 and 126: \ ADVERTISEMENTS. Significant Requi
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Page 133 and 134: ADVERTISEMENTS. THE SPECIJIL FIELD
Page 135 and 136: IN ADVERTISEMENTS ALBUMINURIA OF BR
Page 137 and 138: The Charlotte Medical Journal Some
Page 139 and 140: for typhoid anti-bodies the destruc
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Page 145 and 146: ORIGINAL COMMUNICATIONS. 69 membran
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Page 151 and 152: ORIGINAL COMMUNICATIONS. 75 toxins.
Page 153 and 154: ORIGINAL COMMUNICATIONS, 77 tions a
Page 155 and 156: ORIGINAL COMMUNICATIONS. 79 tion or
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Page 171 and 172: effects of antitoxin treatment and
Page 173 and 174: EDITORIAL. JamesBarrinalectureon J/
Page 175 and 176: EDITORIAL. 99 logically what hither
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Page 181 and 182: J treatment of alcohol and drug add
Page 183 and 184: with their wives, daughters and inv
Page 185 and 186: Countv: Dr. \V. H. Ward, Plymoulli,
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Page 193 and 194: Book Notices. Treatment of the Dise
Page 195 and 196: BOOK NOTICES. 119 rations and to th
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ADBVETISEMENTS. The Girculatorj Dan
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. ABSTRACTS. of the rectus. This op
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INDEX FOR AUGUST. Table of Contents
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m^% ./AMENORRHEA DYSMENORRHEA -": M
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ADVERTISEMENTS. 131 THE CHARLOTTE S
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^tttmai Attest ADVERTISBMRNT3. To o
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ADVERTISHEMTS flp?!lj!uco?ie A most
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ADVERTISEMENTS. St, Luke's Hospital
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' > ' " ' ADVERTISEMENTS. >^^_ ,i&-
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I «43«« ADVERTISEMENTS. MALT IRO
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:': rflflN m WEflKEiT utih- ^ Z^flM
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ADYERTIESMEWTS, Inflammation's Anti
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This is the Food for your baby pati
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VDVERTISEMENTS ERUPTIONS Inflammati
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ADVERTISEMENTS The Success of Liste
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SOUTHERN MEDICAL SOCIETIES. MISSISS
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-'" fî-r/\jRs ÎBR/{}^Y jharlotte
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. // is a fact that ADVERTISEMENTS.
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C ADVERTISEMENTS. BOVININEI Reconst
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ADVERTISEMENTS. ^11 the tfc® Nmtur
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ADVERTISEMENTS Is pre-eminently ser
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ADVERTISEMENTS, Milk prepared with
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f ^ Peak's /^^^*=^=^\ Supporter ADV
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ADVERTISEJIENTS. BUFFALO LITHIA SPR
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ADVERTISEMNTS. I PROF ESSIONAL C AR
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Intestinal ADVERTISEMENTS. ^ '"°'"
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Oar ADVERTISEMENTS THE CHILD THAT F
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The Charlotte Medical Journal Antit
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ORIGINAI, COMMUNICATIONS. 139 tinuo
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ORIGINAL COMMUNICATIONS. 141 tiiict
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ORIGINAL COMMUNICATIONS. 143 by Shu
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ORIGINAL COMMUNICATION. 145 can be
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ORIGINAL COMMUNICATIONS. 147 Americ
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ORIGINAL COMMl'NICATIONS. 149 senti
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The reason for this is that the blo
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ORIGINAL COMMUNICATIONS. 153 chroni
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ORIGINAI, COMMUNICATION. 155 diment
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ORIGINAI. COMMUNICATIONS. 157 maind
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Charlotte Medical Journal EDITORIAL
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' attention, of the ray, and must t
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EDITORIAL. 163 one of the most sign
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165 morbidity from this disease. Ev
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North Carolina Medical College Open
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REVIEW OF SOUTHERN MEDICAL, LITERAT
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REVIEW OF SOUTHERN MEDICAI. LITERAT
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REVIEW OF SOUTHERN MEDICAI, LITERAT
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BOOK NOTICES which he lives, etc.,
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Prognosis In Tetanus.—Patton in T
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ABSTRACTS. 179 amination of every o
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ABSTRACTS. 181 Opium in the Therape
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ABSTRACTS 18,5 pleural pain, and wa
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ABSTRACTS. 185 been removed by lith
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ABSTRACT. 187 a general peritonitis
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Of the patients three were spinster
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ABSTRACTS. 191 —minimal dazzling,
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' ABSTRACTS. • 193 cellulofibrino
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ABSTRACTS. 195 George Lincoln Walto
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AD8VRTISBMBNTS. 197
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ABSTRACTS. juprarenalis. The thyroi
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TABLE OF CONTENTS FOR SEPTEMBER. Ta
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ion ceosed rather abruptly above at
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to heal the sick man as to maintain
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THE ADVERTISEMENTS. CHARLOTTE SANAT
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**< I mi ADVERTISEMENTS. To obtain
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W^mB ADVERTISEEMTS A most powerful
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UNpT. il ADVERTISEMENTS. Aseptinol
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ADVERTISEMENTS. ^^^2ZSi^^ aohannfoj
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If Interested "Êwp FOR Samples h L
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^-MiMi^^ ADVERTIESMENTS, (Inflammat
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A physiologically correct food. A
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VDVERTISEMENTS ERUPTIONvS Inflammat
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SOUTHERN MEDICAL SOCIETIES, MISSISS
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ADVERTISEMENTS. In TREATING BRONCHI
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c ADVERTISEMENTS. BOVmiNE Reconstru
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ADVERTISEMENTS. Does not cause the
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lDVERTISEMENTS Is physiologically a
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ADVERTISEMENTS, IX PANOPEPTON Consi
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^ Peak's \ Supporter ADVERTISEMENTS
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ADVERTISEMENTS. BUFFALO LITHIA SPRI
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—— ADVERTISEMNTS. I PROF ESSION
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Intestinal ADVERTISEMENTS. Dyspepsi
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ADVERTISEMENTS NEURASTHENIC "BREAKD
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The Charlotte Medical Journal Vol.
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ORIGINAL COMMUNICATIONS. 215 a dise
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ORIGINAL COMMUNICATIONS, 217 any of
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ORIGINAL COMMUNICATION. 2l9 accurac
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ORIGINIAL COMMUNICATIONS. 221 of an
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ORIGINAL COMMUNICATIONS. 223 in spi
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ORIGINAL COMMUNICATIONS. 225 i the
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ORIGINAL CO.MMUNICATIONS. 227 branc
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ORIGINAL COMMUNICATIONS. 229 where
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ORIGINAL COMMUNICATIONS. 231 the dr
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1 fraction ORIGINAL COMMUNICATIONS.
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ORIGINAL COMMUNICATIONS. 235 But th
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. ORIGINAL COMMUNICATIONS. ant ones
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ORIGINAL COMMUNICATIONS, 239 aftern
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ORIGINIAL COMMUNICATIONS. 74 J firs
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Charlotte of t^ê Medical problem J
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works, making a total of 21n deaths
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DR. llô^^'OK COOK, DISCOVERER, lie
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EDITORIAL. 249 of a tetanic nature.
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EDITORIAL. T-< ^^:hjS^^' ->^'- - S-
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J I Board i the EDITORIAL. 253 affo
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A Case ol BaclIIary Infection of th
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ABSTRACTS. indicates that a point n
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ABSTRACTS. 261 should be added thos
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ABSTRACTS. 263 sat up ill bed on th
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ABSTRACT. 7^5 sore throat that are
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ACTS 267 The Etiology ot So-Called
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nig of the spongy layer. This occur
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ABSTRACTS 271 1 It should be so adm
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AUBVKTISEMENTS. A considerable prop
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iig, immediate ligature is preferab
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TABLE OF CONTENTS FOR OCTOBER. 277
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ufactuiî, Katherine L. Storms, M.
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ABSTRACTS. Electricity in Ibe Diagn
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ADVERTISEMENTS. THE CHARLOTTE SANAT
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ADVERTISEMRNTS. B-^^'^»^BS fa For
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ADVKRTlSHK.MTS A most powerful non-
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ADVERTISEMENTS. St Luke's Hospital
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ADVERTISEMENTS. Ascftinol Manufactu
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— ADVERTISEMENTS. MALT WITH REPRE
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Ê BRIDGE BETWEEN DI6EA5E and MEALT
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ADVERTIESMENTS, HUMAN HANDS HAVE NO
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ADVERTISEMENTS. You are more assure
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VDVERTISEMENTS The First Applicatio
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SOUTHERN MEDICAL SOCIETIES, MISSISS
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'^"^^*^'^3«»v Iharlotte Medical J
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ADVERTISEMENTS. Id MEET Yhreatening
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ADVERTISEMENTS. i=[>iui;ii;ij wm Re
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ADVERTISEMENTS. Successfully Prescr
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ADVERTISEMENTS ^-Xc^xjui'sJiJ^tenoi
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THE I "I I) ADVERTISEMENTS, s Essen
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TASTELESS ADVERTISEMENTS. WHY Water
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ADVERTISEMENTS. XIII LITHIA SPRINGS
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ADVERTISEMNTS. ? :$:?: - >:?:$: - >
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t^-^-''' ADVERTISKiMENTS. >r,T-ini
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lDVERTISEMENTS THE ILLS Oh THE AGED
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; !;> The Charlotte Medical Journal
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ORIGINAL COMMUNICATIONS. 291 that a
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ORIGINAL CO.MMCNICATIONS. 203 pubii
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ORIGINAL CO^niUNICATIONS. 295 quack
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ORIGINAL COMMUNICATIONS. 297 sand o
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ORIGINAL COMMUNICATIONS. 299 stitut
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a unit work to this end and it will
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ORIGINAL COMMUNICATIONS. nobility.
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ORIGINAL COMMUNICATIONS 30S covered
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ORIGINAL COMMUNICATION. 307 of the
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, ORIGINAL COMMUNICATIONS. 309 u- i
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KDITORIAL. Charlotte Medical Journa
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EDITORIAL. 313 assumption on the ph
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EDITORIAL. 315 definite locations,
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EDITORIAL. -,jy '^ """''"' S. C.i D
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EDITORIAL. AI
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EDITORIAL. 321 EDITORIAL NEWS ITEMS
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EDITORIAL. 323 solely of addresses
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EDITORIAL. -,,r Soci^r'"'' '' ''" '
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ABSTRACTS. 397 the iiKliyidual girl
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ABSTRACTS 329 ble nurse—provided
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ABSTRACTS. ^'°" '''" ^"^' ""^'^ °
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BOOK NOTICES -,.. of Preventive Med
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ABSTRACTS. hyj,e,nc pnncples. Where
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ABSTRACTS. 337 spinal fluid of epil
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ABSTRACTS. -,^q in which, in anv ev
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ABSTRACTS. 341 then there has been
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ABSTRACTS 343 Antilormln in the Det
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I harmless. I peculiarly Calcium Sa
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ABSTRACTS. :over chancres on the li
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AUEVKTISE.MliNTS. 349 A considerabl
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REVIEW OF SOUTHERN MEDICAI, LITERAT
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TABLE OF CONTENTS FOR NOVEMI Table
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ABSTRACTS. 359 DOCTOR: OUR RESPIRAZ
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ADVERTISEMKNTS. For Upwards of Fort
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ADVERTISHEMTS A most powerful non-t
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Balttmore^Md. Pine Ridê Sanitoriii
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ADVERTISEMENTS. Bt-a—ygr-n^TT^fl
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fflflN ITi WEflKEJT UNK- IT 15 NOT
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ADVERTIESMENTS, HUMAN HANDS HAVE NO
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ADVERTISEMENTS. after circumcision
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VDVERTISEMENTS Instantaneous Is the
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SOUTHERN MEDICAL SOCIETIES. MISSISS
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Charlotte Medical Journal. A SOUTHE
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ADVERTISEMENTS. lo Meet Ihreateninc
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c ADVERTISEMENTS. BOyiNINE Reconstr
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ADVKRTISEMENTS. A.II the i« ^mdL®
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ADVERTISEMENTS DR. STEEDLY'S PRIVAT
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ADVERTISEMENTS, Fairchild's Essence
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ADVERTISEMENTS. W LgLtest Scientifi
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BUFFALO ADVERTISEMENTS. XIII ALBUMI
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ADVERTISEMNTS. I PROF ESSIONAL CARD
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OE3 ADVERTISEMENTS. I o n Quihgesim
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ADVERTISEMENTS THE ANEMIA OF BRIGHT
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j j 1 The Charlotte Medical Journal
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ORIGINAI, COMMUNICATIONS 367 diagno
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— ORIGINAL COMMUNICATIONS. 369 Dr
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ORIGINAL COMMUNICATIONS. !...v.ed I
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ORIGINAL COMMUNICATION. 373 Iter in
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ORIGINAL COMMUNICATIONS. 375 )f the
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ORIGINAL COMMUNICATIONS. 377 no occ
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ORIGINAL COMMUNICATIONS --n Û.: ra
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ORIGINAL COMMUNICATIONS. 381 ffiveh
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ORIGINAL COMMUNICATIONS. 383 i desi
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, ORIGINAL COMMUNICATIONS, ."iS.S o
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ORIGINIAL COMMUNICATIONS. .'iS? is
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EDITORIAL. .389 Charlotte ture prop
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EDITORIAL. 391 ation of information
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EDITORIAL. 393 decrease of urinary
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[ ! his I to DK. RUSSEUU MOVES TO f
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man and Dr. li. Eugene Mitchell, of
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. EDITORIAL. 3^9 J. S. Wynne, Dr. A
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EDITORIAL. 40] . ; . ellagra," Dr.
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BOOK NOTICES 405 . 1 This book is i
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ABSTRACTS. 407 ical Society, contri
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ABSTRACTS 409 Certain Bacillus Coll
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ABSTRACTS. at this Stage to check t
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Bl^tr:i:îê:S':::r^^'^:^: ;J;-Pati
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ABSTRACTS. 415 tastases and recurre
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Clinical ADEVRTISEMENTS. FUNCTIONAL
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ADVERTISEMENTS. 419 ra For Upwards
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Tblosinamlne In Deafness.— Mollis
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p was a notorious one. He not only
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TABLE OF CONTENTS FOR VOLUMI Table
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py, bv Edwin Henry 8cborer, M. !) U
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tZ^ ADVEKTISEMKNTS. A Post Graduate
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fidgetiness, especially at night. T
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I actually I ! tion i dition j I be
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ADVERTISEMENTS. DOCTOR: OUR RESPIRA
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ADVERTISEMKKTS, 4,37 A S-Pheu, form
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ADVKKTISKHMTS A most powerful non-t
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:«^ ADVERTISEMENTS. 'Ai Asepttnol
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VDVERTISEMENTS The First Applicatio
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Ir Interested Send for Smpics n LiT
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ADVIiRTIESMENTS, HUMAN HANDS HAVE N
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I 'A ADVERTISEMENTS. For your littl
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m I Sy R E P R E S E NTS THE M O ST
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Vol. 60, 1909 - University of North Carolina at Chapel Hill

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