Vol. 60, 1909 - University of North Carolina at Chapel Hill

210
THE'CHARLOTTE MEDICAL JOURNAL.
derstand more fully the complexities of im- pure, crystalline form from the seeds of
munity which pievail in the animal world. Strophanthusgratus. This gratus-strophan-
—London Medical Lancet.
thin Thorns, manufactured by Merclc, was
^ employed in 3>2 patients bv P. Fleischmann
The dose given for
.
strophanthin is usually h to 1 Mgm:, but
Francesco Fulci, after going over the
^^^j^ ^^^ p^^.^^ cr>'stalline preparation no
literature with reference to the possible oc- i.^
^^^^ ^^^^^^ Mgm. should be injected,
currence of tuberculous endocarditis, sums
^j^^ j-gg^^g gf a„ injection are very evident;
up by saying thai the opinions of authors
ygj-y soon the pulse will slow, 'the pulse
are still at variance as to the possibility of
amplitude rise, and within three hours
Tuberculous Endocarditis. and H Wjasmensky .
its occurrence. Perhaps these lesions are
(jj^^jegis begins. The lowest pulse-rate is
merely toxic, not caused by the actual
^^^^^^^ between six to eight minutes up to
presence of tubercle bacilli. This theory
ggveral hours after the injection. The durais
supported by the absence of specific bac-
^j^^^ ^f a^lion varies with the ease: someterial
lesions and of speciffc histological
^^^^^ j^ j^ ^jg^ desirable to give digitalis or
formations. Lesions of the same kind can
^^^^^ j^^^j.^ ionics. The best results are
be produced in dogs by injection of emulalways
seen in cardiac decompensation; less
sion of bacillus of Koch into the carotid
gjjgj,^ jg evident in pneumonia, scarlet, and
artery, after ligature of the ureter made the
^^^^^ infections, while the tarchycardia of
day before the injection. The result is spepj^t^isis,
carcinoma, etc., is usually not re-
cific granulations disseminated over the in-
'
^^^^^] l^^ ,5,,^ ^ase of Basedow's disease
ternal surface of the left ventricle and au-
^^^ p^j^^ ^^,^^^ increased in frequency. Unricle,
the aorta, and ventricular surface of
^Q^aj-d effects are seen very rarely, but the
the aortic valves. This tuberculosis may
^^^^ should not be too high in cachexia,
be produced without any trauma of the
Cumulative effects should be guarded
heart, either by direct injection of the speagainst,
particularly if the patient has been
cific bacilli into the heart, or by carotid injoking
digitalis.—Deutsch. med. Woch.
jeclion after suppression of the kidney . .
function. The examination of the lesions Etbylmorpliine Iodide in Opbttaalmology
showed necrotic, inflammatory, and reactethylmorphine
hydro-
,ve phenomena. The bacteriological ex-
^Me, has earned a well-established place
amiiiation showed few bacilh in the supe^^
ophthalmology, and quite recently the
fical fibrinous deposits vvhen the germs
^^^J^^^^^- j^^^ide has been recommendwere
injected into the blood. The author
^^^ ^,^,^^^^ diseases. F. R. v. Arlt
sums up two groupsof experiments on an-
[ ^^ ^^^ ^^^
imals made by himself thus: he dissents
^oes not dissolve quite as readily as dionin.
from the opinions expressed by others m
,,^^ of g^'u in the tears is importthat
he obtained no granules that were un- ^ P
J^
^^ ^^^ ^^,^_
doubtedly tuberculous: he never succeeaed
g'^'^^^^^ ^igg^i^e more readily in a salt soluby
endovenous injection 111 producing un^ ^
^^ ^^ ^.^^^ ^^ introduced
doubted inflammatory alterations of the
j^^o the eye with some salt, the pain' will
valves: Marchiafava after years of obser-
^, j^g, ^,\ked than with dionin alone. As
vat.ou never encountered specific endocar^
therapeutic activity is concerned, the
dial lesions in tuberculous subjects.-ll
.^^.^^ .^ skid to be equally as valuable as
i-oliclinico.
dionin, and is perhaps to be preferred for
Stropbantbin in Pure Form. children.—Therap, u. Hygiene.
The desire to standardize accurately
potent heart tonics, such as digitalis, has
led to the introduction of the term "'frogunit."
This refers to the amount necessary
Dyspepsia in Malarial Subjects.
V. Raymond and L. Salignat have had
under treatment at Vichy many cases of
to cause systolic rest within thirty minutes
of the heart of rana temporaria, weighing
chronic malaria contracted in tropical
countries, in which they have found chronic
30 to 40 Gm. Since the various prepara- dyspepsia to exist. In thirty of these cases
tions are not, however, ab.sorbed equally they have made accurate determinations of
fast from the lymph-sacs of the frog, it is the stomach contents and gastric chemistry.
a much better plan to employ principles They found that in 53 per cent, there was
known to be chemically pure. Strophan- hyperchlorhydia, in 33 per cent, normal
thin has latterly been employed for intra- chemism, and in 13 per cent, hypochlorhyvenous
use, where quick action is desired, dria. These troubles are found in recent
Most specimens of this glucoside are im- as well as chronic cases of malarial poisonpure
and amorphous, but recently Thorns ing, and are the results of various stages of
has succeeded in isolating the principle in the disease. The liver and spleen are also