Vol. 60, 1909 - University of North Carolina at Chapel Hill

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THE CHARLOTTE MEDICAL JOURNAL.
writer throws some light upon the nature staphylococcus aureus from which a vacof
the skotographic action manifested by cine was prepared and a dose of 25,000,000 ]
animal tissues and certain other substances, staphylococci were administered. In three i
comparingtheir behavior with that of woods days improvement was noticed. Later an- l
in which the action has been regarded as other injection of the patient's own staphydependent
upon the formation of hydrogen lococci were given. The blood withdrawn \
peroxide, and with that of recognized radio- clotted almost immediately and, therefore, ,
active suostances. On this point he ad- one-dram doses of citric acid were adminis- ;
duces evidence showing that the animal tered every four hours for four doses. The j
tissues and other substances under examin- patient made an uneventful recovery, the I
ation cannot, so far as their action upon a only sign of illness left being a dimple on i
photographic plate in the dark is concerned, the left cheek caused by the skin becoming ;
be grouped conclusively with the recognized attached to the mucous membrane of the
radioactive substances or segregated into a cheek just over the opening of Stenson's I
class such as that formed by the woods, and duct.
believed by Russell to affect a photographic i
plate in the dark by means of a purely A Case ol Acute Lupus Erylliematosus. ,
chemical action. They occupy an inter- —McDonagh, in the Glasgow Medical
mediate position and have affinities with Journal, reports such a case occurring in a ;
the woods on the one hand, and with the female, aged fifteen, who was admitted to I
recognized radioactive substances on the the hospital March 12, 1907. She first
other. Lastly, MacCormac has shown that noticed her hands gradually becoming blue i
bacteria may be divided into groups accord- and numb. A few weeks later the feet ;)
ing to their skotographic power, and that likewise became affected. For some years j
the only group which acts in this way with previously she had suffered from chilblains,
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constancy and to a marked degree is a small On admission to the hospital the fingers i
one, which includes the pyogenetic staphy- and toes were bluish, showed old scars, and j
lococci and the bacilli of tuberculosis and were cold to the touch. There were some j
diphtheria. The bearing of these observa- blotchy red patches on the face. The nos? i
tions upon the question of carcinoma he in- and ears were normal. A few days after
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tends to treat in his third lecture. admission a red rash appeared all over the
face and on both wrists extending up to the •
A Case ol Severe Facial Carbuncle, forearms, being accompanied by a persist- I
with Ludwig's Angina and Parotilis.— gntly raised temperature. No hemoglobin- i
Walters and Solly, in The London Prac- uria was found. On March 26, the face '
titioner, report such a case successfully became much worse, the nose appeared .j
treated by vaccine, combined with the ad- cyanosed, and albumin appeared in the i
ministration of repeated doses of citric acid, urine. On April 3, the nose became very ',
The patient was a girl of seventeen. A sore and swollen, also the upper lip, and <
pimple was first noticed on the right cheek, the patient breathed almost entirely through ;
which was squeezed but no pus exuded, the mouth. On April 12 the face, the hands, j
Two days later she had a hard indurated and the feet were better, but patches of ery- i
inflammatory mass about the size of a shill- thema appeared on the arms and a papular v
ing on the right cheek adjoining the lip. eruption on the back. On April 23 the face "1
The temperature was 99° F. Soon the upper was diffusely pigmented and erythematous; I
lip on the right side began to swell and pus it was covered all over with scales, some of 'i
discharged by many small holes from its which came off easily, others being adher-
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under surface and the lower lip began to ent; the latter on removal had those pro- !|
swell. Soon the whole of the right cheek cesses of horny tissue which fitted into if
was dusky in color, with an indurated swell- small depressions on the skin, and which j
ing extending upward from the lip, the eye are typical of lupus erythematosus. On .\
being nearly closed and the groove on the having the hair cut short typical plugs and 'j
side of the nose nearly obliterated. She scarring were found. The scalp, like the ']
was almost unable to open her mouth, there face, was diffusely pigmented anderythem- \
were sordes on the teeth, and her tongue atous. A small papulosquamous eruption |1
was very foul. There was no fluctuation covered the neck and chest. An atrophic ,1
present. The temperature was 103° F., the condition of the skin had spread up the ;f
pulse 140; the patiejit was somewhat drowsy, back of the hands to about the middle, <
semi-delerious, and evidently very ill. A where the scarring was less marked, and t
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dose of 50,000,000 staphylococci (mixed when present was covered with scales and ji
stock vaccine > was
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inoculated. The next surrounded by a zone of erythema. As else-
day there was not much change. On the where, many of the scales on removal pes- jg
day following a culture taken from the sessed the horny processes. Later she was j.1
pustule of the lip gave a pure growth of brought to the hospital with all the signs of j'j
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