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Vol. 60, 1909 - University of North Carolina at Chapel Hill

Vol. 60, 1909 - University of North Carolina at Chapel Hill

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REVIEW OF SOUTHERN MEDICAI. LITERATURE. ]71<br />

probably due to the leucocytosis gener<strong>at</strong>ed<br />

by the horse serum alone th<strong>at</strong> it might be<br />

well to tuni our <strong>at</strong>tention to agents th<strong>at</strong><br />

have to do with bringing up the white blood<br />

cell number, and then stimul<strong>at</strong>e the white<br />

blood cell, say <strong>of</strong> the horse, to protection<br />

by injecting dead streptococci—and instead<br />

<strong>of</strong> trving to get an antitoxin in the serum<br />

<strong>of</strong> the horse—extract the leucocytes by<br />

centrifugal means, and make an emulsion<br />

<strong>of</strong> the white cells, for in them we have only<br />

the protective agent against the streptococci.<br />

The same precaution probably would<br />

have to be observed—as in antitoxin, to get<br />

several varieties <strong>of</strong> streptococci, or probably<br />

by culture media develop ihe streptococci<br />

to its typical long chain-form: all other<br />

varieties being probably lowed in the evolutionary<br />

stage from the sophrophyte to the<br />

oblig<strong>at</strong>e micro-parasite.<br />

Mrginia Medical Semi- Monthly, July 9lli,<br />

Tre<strong>at</strong>ment oi Consumption.— Dr. W. 11.<br />

C<strong>of</strong>fman says lii<strong>at</strong> a p<strong>at</strong>ient who is bleeding<br />

freely should be put to bed as soon as<br />

possible, and should be propped straight<br />

up, comfortable, with a bowl or other large<br />

receptacle containing a little w<strong>at</strong>er, in his<br />

lap, so th<strong>at</strong> when the gushes <strong>of</strong> blood come<br />

he may be able to dispose <strong>of</strong> them with the<br />

least possible exertion. He should be kept<br />

iu bed for <strong>at</strong> least ten days after the bleeding<br />

is over, because it takes about this<br />

length <strong>of</strong> time for the organiz<strong>at</strong>ion <strong>of</strong> the<br />

clot, which is n<strong>at</strong>ure's means <strong>of</strong> stopping<br />

the bleeding. lie should have a small<br />

hypodermic <strong>of</strong> morphia to control the cough<br />

and the nervousness from which so many<br />

bleeding p<strong>at</strong>ients suffer.<br />

Of drugs, nitrite <strong>of</strong> amyl is probably the<br />

only one th<strong>at</strong> has any immedi<strong>at</strong>e effect on<br />

pulmonary hemorrhage. Calcium chloride<br />

is said to be useful in controlling the tendency<br />

to bleed. It may be given in five<br />

grain doses e\ery three hours, until five or<br />

six doses haveVieen given; then, three times<br />

daily for about three days.<br />

Many cases may be controlled by lowering<br />

the blood pressure. This may be done<br />

by giving large doses <strong>of</strong> epsom salt: also,<br />

by the use <strong>of</strong> such remedies as ver<strong>at</strong>rum<br />

viride.<br />

In vieiv <strong>of</strong> the fact th<strong>at</strong> any p<strong>at</strong>ient with<br />

an open cavity is liable to bleed, it is well<br />

to have an occasional record <strong>of</strong> his blood<br />

pressure, so th<strong>at</strong> when he does bleed you<br />

will Ije in a position to know when you<br />

have reduced the blood pressure enough.<br />

Fifteen to twenty points are usually sufficient.<br />

'I'here are, however, a few cases<br />

in which ver<strong>at</strong>rum viride does no good,<br />

th<strong>at</strong> are promptly checked by the use <strong>of</strong><br />

adrenalin. It is probably well to restrict<br />

for one or two days after a hemorrhage the<br />

p<strong>at</strong>ient's r<strong>at</strong>ional food, or, <strong>at</strong> least, the<br />

fluids.<br />

Etiology and P<strong>at</strong>bology <strong>of</strong> Summer<br />

Oiarrbeas ol Children.— Dr. E. P. Torupkins<br />

points out th<strong>at</strong> <strong>at</strong> one time it was<br />

thought th<strong>at</strong> sterilizing would do away with<br />

most if not all the bad effects <strong>of</strong> impure'<br />

milk. But sterilized milk is cooked milk,<br />

and N<strong>at</strong>ure never intended babies to live<br />

on cooked food. He<strong>at</strong> sufficient to kill<br />

some <strong>of</strong> the harmful bacteria is sufficient<br />

also to destroy the beneficial ones which<br />

hold in check or destroy the dangerous<br />

ones. Yet this is not all the damage he<strong>at</strong><br />

will do, and a lower degree <strong>of</strong> he<strong>at</strong> even<br />

than th<strong>at</strong> required to kill the microbes. For<br />

instance, Hippius and Spolverini have<br />

proven the presence, both in mothers' milk<br />

and in cows' milk, <strong>of</strong> a ferment which is<br />

destroyed or enfeebled by only a moder<strong>at</strong>e<br />

amount <strong>of</strong> he<strong>at</strong>. Spolverini says th<strong>at</strong> the<br />

steriliz<strong>at</strong>ion <strong>of</strong> milk produces six disadvantageous<br />

changes in it, namely:<br />

First.—It expels the carbonic acid gas<br />

which stimul<strong>at</strong>es the secretion <strong>of</strong> the gastric<br />

juice.<br />

Second.—Diminishes the amount <strong>of</strong> lime<br />

and free phosphoric acid, increases the insoluble<br />

calcium phosph<strong>at</strong>e, and precipit<strong>at</strong>es<br />

the anti-scorbutic citric acid.<br />

Third.—Destroys a large part <strong>of</strong> the lecithin<br />

<strong>of</strong> the nucleiu.<br />

Fourth.—Coagul<strong>at</strong>es the soluble albumin<br />

and changes and renders unabsorbable the<br />

casein.<br />

Fifth.—Unites the f<strong>at</strong> globules in larger<br />

masses which are less easily digested and<br />

absorbed.<br />

Sixth.— Destroys or weakens the ferments,<br />

and thus are lost to the child antitoxic<br />

and immunizing compounds <strong>of</strong> gre<strong>at</strong><br />

value.<br />

Scarlet Fever.— Dr. J. D. Morgan says<br />

th<strong>at</strong> if there is one thing he is positive about<br />

in scarlet fever it is th<strong>at</strong> suitable warmth to<br />

the body and milk diet give the best results.<br />

It was Jaccoud who laid such stress upon<br />

the sole use <strong>of</strong> milk. There are few or no<br />

cases th<strong>at</strong> do not show a trace or more <strong>of</strong><br />

albumin; and time and again the p<strong>at</strong>ients<br />

have been given animal broths, eggs, etc.,<br />

only to see the albumin increase. Thompson<br />

regards nephritis as part <strong>of</strong> the disease,<br />

and urges care in the diet, which should be<br />

milk and cereals for the first three weeks.<br />

K. Oppenheimer warns against allowing<br />

the p<strong>at</strong>ient to become chilled. The diet,<br />

he says, is more important than in any<br />

other infectious disease, on account <strong>of</strong> the<br />

tendency to nephritis. Rubens holds his<br />

p<strong>at</strong>ients to strict dietetic measures, avoid-'

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