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Vol. 60, 1909 - University of North Carolina at Chapel Hill

Vol. 60, 1909 - University of North Carolina at Chapel Hill

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XXXII THE CHARLOTTE MEDICAL JOURNAL<br />

may be associ<strong>at</strong>ed with other nervous trou- congenital or tertiary acquired syphilis, has<br />

bles in cases th<strong>at</strong> show evidences <strong>of</strong> syphilis, sometimes seemed <strong>of</strong> value Repealed lumor<br />

they may occur suddenly in children bar puncture has been used with some,<br />

th<strong>at</strong> have given no evidences <strong>of</strong> syphilis, though probably only with temporary, bene-<br />

They may be preceded by symptoms <strong>of</strong> ma- fit. P<strong>at</strong>ients should be advised to eschew<br />

laise or convulsions for a few days. Such alcohol, tea, c<strong>of</strong>fee, and tobacco, to avoid<br />

hemiplegias may disappear entirely under as far as possible mental excitement and<br />

specific tre<strong>at</strong>ment in a few weeks or months, loud noises, and to keep the bowels acting<br />

or there may be left a variable amount <strong>of</strong> well. During a severe <strong>at</strong>tack the recumimpotence<br />

and <strong>at</strong>rophy, corresponding to bent posture should be enjoined, with ice to<br />

an area <strong>of</strong> brain s<strong>of</strong>tening due to obstruc- the side <strong>of</strong> the head. When all other meastion<br />

<strong>of</strong> some one artery. These conditions ures fail, and when life is made practically<br />

are entirely similar to the specific hemi- intolerable, the advisability <strong>of</strong> destroying<br />

plegias <strong>of</strong> adults, which are <strong>of</strong>ten <strong>of</strong> a pass- the labyrinth—<strong>at</strong> any r<strong>at</strong>e the st<strong>at</strong>ic portion<br />

ing n<strong>at</strong>ure, and are caused by cerebral <strong>of</strong> it—should be entertained,<br />

arteritis with ischemia. Whenever we have<br />

^^ Tre<strong>at</strong>ment ol Acute Rheum<strong>at</strong>ism.<br />

a sudden hemiplegia in a child we may look ,...,,„,<br />

forsvphilis, even if there are no other signs —Plehn (Deutsche medicinische Wochen<strong>of</strong><br />

its presence.— Revue de Medecine. schrift) emphasizes the wrong principle<br />

appears to be gaining ground, to<br />

^ which<br />

Aural Vertlgc-Simon, in The British ^^^^^^^ ^f their supposed toxic effects on<br />

Medical Journal, says th<strong>at</strong> as regards tre<strong>at</strong>- ^j^^ kidneys. Leuthje was the first to detnment,<br />

this n<strong>at</strong>urally has reference to the Q^^rale the changes in the urine which are<br />

underlying aural affection, and iii giving a<br />

. ^, . . ^ , throw overboard the older salicyl<strong>at</strong>es, on<br />

^^t .^jje,, salicyl<strong>at</strong>es are given even in<br />

prognosis one has to take into consider<strong>at</strong>ion<br />

^^^der<strong>at</strong>e doses. Klemperer considered th<strong>at</strong> *<br />

the possibility <strong>of</strong> the amelior<strong>at</strong>ion <strong>of</strong> this -^ -^ „ecessarv to use the smallest doses poscond.tion,<br />

and also the period <strong>of</strong> associa-<br />

^^^^^ -^^ ^^^^^ ^,^^ ^^ ^^p^^^ ^^^ kidneys to I<br />

'<br />

tion <strong>of</strong> the deafness and vertigo In non-<br />

^^^^ ^^^.^ influence. Hauffe, representing<br />

suppur<strong>at</strong>ive affections <strong>of</strong> the middle ear in<br />

^^^ Schweninger school, which refuses all ;<br />

which the vertigo has shown itself much<br />

^jgdicamental tre<strong>at</strong>ment, claims to have |<br />

l<strong>at</strong>er than the deafness or timitus, it has<br />

obtained excellent results without salicylic<br />

seemed to the author th<strong>at</strong> the tre<strong>at</strong>ment <strong>of</strong><br />

^^-^ 1<br />

However, closer investig<strong>at</strong>ion has<br />

the aural condition was more likely to lead<br />

^^^^^^^ ^^^^ ^^^ ^^^^^ irrit<strong>at</strong>ion <strong>of</strong> salicylic<br />

to its improvement or disappearance In ^^.^ -^ ^^^^ imagined than real, and ! th<strong>at</strong><br />

tre<strong>at</strong>ing the symptom itself the drug <strong>of</strong> most<br />

^^fgctly normal, healthy persons frequent- i<br />

efficacy is quinine. Charcot instituted tins ,<br />

^ jj^.,,^^^^ j^^^^^ <strong>of</strong> 'albumin, and even<br />

tre<strong>at</strong>ment on the principle th<strong>at</strong> It gradually '<br />

^ vvithout taking any <strong>of</strong> this drug.<br />

destroyed the hearing, when, as it has been<br />

^j^^^^ ^_^^^^ ^f albuminuria not infrequen - :<br />

seen the vertigo disappears. On the other<br />

j^ ^^^^^ ^^j^il^ ^^^ ^^^-^^^^ -^ ^^^-^^^ g^,j. j<br />

hand. Urban Pritchard reports a case <strong>of</strong> se- ^j^^^^<br />

^^ considers th<strong>at</strong> even if slight |<br />

vere vertigo from a poisonous dose <strong>of</strong> qui-<br />

:<br />

i^.^-^^.^^^^^, ^f the renal appar<strong>at</strong>us were pronine.<br />

It is, however, not necessary to give<br />

^^^^^ ^^ ^^^-^ ^^^^^ ^-^^^^ -^ acts specifically ,<br />

It m such large doses. Given a gram <strong>at</strong> a .^^ rheum<strong>at</strong>ic fever, just as mercury acts in ,!<br />

time. It seems to reduce the irrit<strong>at</strong>ion <strong>of</strong> the<br />

^jJHs and quinine in malaria, it would be i<br />

vestibular nerve, probably by overcoming ^-^^ ^^ ^-^^ -^ f^^^^^ ^.j^^ ^^^i^^^ g^y^ ^^^^ j<br />

congestive changes.<br />

j^ -g „ecessary to give it in large quantities j<br />

On the ground th<strong>at</strong> vertigo is due to ane- j^ order to obtain the full specific effects,<br />

mia <strong>of</strong> the labyrinth—which, however, is pjrst, however, it must be certain th<strong>at</strong> the<br />

probably not as a rule well founded— Ler- rheum<strong>at</strong>ic affection is really acute. He<br />

moyez suggested the use <strong>of</strong> amyl nitrite, prefers pure salicylic acid to the sodium or<br />

We are all aware, <strong>of</strong> course, th<strong>at</strong> in condi- other salts. Plehn g\ves it in doses <strong>of</strong> 1<br />

tions <strong>of</strong> severe anemia vertigo is common, gramme (th<strong>at</strong> is, about 16 grains) every<br />

but whether this is an aural phenomenon hours, or 0.5 gramme every hour during<br />

or not, even when associ<strong>at</strong>ed, as it <strong>of</strong>ten is, the first day, but none during the first night,<br />

with tinnitus, is a doubtful point. At the Qn the following days he gives 6 grains in<br />

same time it is quite probable th<strong>at</strong> the actual i.,. or 1-gramme doses. This is continued<br />

cause <strong>of</strong> vertigo is not so much either con- until the temper<strong>at</strong>ure has been normal for<br />

gestion or anemia as the alter<strong>at</strong>ion in the three days and all pains and complaints <strong>of</strong><br />

pressure <strong>of</strong> the endolymph which may be all sorts have disappeared. Then he gives<br />

brought about by either <strong>of</strong> these st<strong>at</strong>es. The 4 grammes a day for a week, and after three<br />

bromides and iodides are sometimes useful, further days, during which the p<strong>at</strong>ient reand<br />

pilocarpine, especially in p<strong>at</strong>ients in mains in bed but receives no salicylic acid,<br />

whom the aural condition is dependent on i^g allows him to get up, provided th<strong>at</strong> no

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