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Vol. 60, 1909 - University of North Carolina at Chapel Hill

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Miscellcincous.<br />

THE CHARLOTTE MEDICAL JOURNAL.<br />

Appendicitis and Adnexitis.<br />

Henry Hartraaini describes appendicitis<br />

accompanying adnexitis as Ijeing conveyed<br />

by way <strong>of</strong> the peritoneum, there being no<br />

direct connection between these structures<br />

by way <strong>of</strong> the blood-vessels or lymph<strong>at</strong>ics.<br />

In the woman the appendix frequently descends<br />

into the pelvis by pressure <strong>of</strong> the intestines<br />

and <strong>of</strong> the corsets. Diagnosis is<br />

somewli<strong>at</strong> difficult before oper<strong>at</strong>ion. Pain<br />

is generally loc<strong>at</strong>ed lower down in adnexitis<br />

than in appendicitis. The history <strong>of</strong> the<br />

case is <strong>of</strong> value. The absence <strong>of</strong> a history<br />

<strong>of</strong> menstrual troubles and ascending infection<br />

is in favor <strong>of</strong> appendicitis. The picture<br />

<strong>of</strong> peritonitis is more marked in appendicitis,<br />

the expression is more anxious, the<br />

sensibility <strong>of</strong> the abdomen and the distension<br />

are gre<strong>at</strong>er. Temper<strong>at</strong>ure is more elev<strong>at</strong>ed<br />

and the condition is progressive, while<br />

after a time in adnexitis it is regressive.<br />

Tre<strong>at</strong>ment demands immedi<strong>at</strong>e oper<strong>at</strong>ion<br />

as soon as a diagnosis is arrived <strong>at</strong>.—Annales<br />

de Gynecologic et d'Obstetriques.<br />

Tre<strong>at</strong>ment <strong>of</strong> Some <strong>of</strong> the Severer<br />

Forms oi Headaclic.—Harris (Brit. Med.<br />

Jour. ) in discussing this subject classifies<br />

the causes <strong>of</strong> headache as A, Superficial.<br />

1, Diseases <strong>of</strong> brain coverings; a, scalp; b,<br />

pericranium; c, bone; 2, reflex visceral neuralgias<br />

<strong>of</strong> the scalp. B, Deep. 1. Reflex<br />

cortical neuralgia. 2. Toxaemic. 3. In<br />

creased intracranial pressure.<br />

Diseases <strong>of</strong> the brain coverings are due to<br />

morbid processes as rheum<strong>at</strong>ism, syphilis<br />

and tuberculosis and should be tre<strong>at</strong>ed as<br />

such. Reflex visceral and cortical neuralgias<br />

are best tre<strong>at</strong>ed by rest and anti-neuralgic<br />

remedies as phenacetin, pyramidou<br />

and th<strong>at</strong> class <strong>of</strong> drugs. Toxamic headaches<br />

are tre<strong>at</strong>ed by establishing a regular<br />

daily habit <strong>of</strong> the bowel. Increased intracranial<br />

pressure causes the most severe<br />

headaches and are usually only relieved by<br />

the use <strong>of</strong> the trephine. If due to meningitis,<br />

lumbar puncture may bring relief or<br />

leeches applied to the temples or back <strong>of</strong><br />

the ears. The tre<strong>at</strong>ment <strong>of</strong> migraine he<br />

divides into local and indirect by lowering<br />

general blood pressure. The first includes<br />

trephining, lumbar puncture, leeches to the<br />

scalp, foment<strong>at</strong>ions, hot bottles or ice bags.<br />

The second includes nitroglycerine and<br />

nitritis, opium, aconite, chloral, phenacetin,<br />

antipyrin, purg<strong>at</strong>ion, diaphoresis and a hot<br />

b<strong>at</strong>h. Harris has had good success by applying<br />

leeches to the .scalp, giving 10 grains<br />

<strong>of</strong> Dover's powders, with a hot drink containing<br />

'6 grain <strong>of</strong> pilocarpin and keeping<br />

the p<strong>at</strong>ient warmly wrapped so as to promote<br />

pefspir<strong>at</strong>iou.<br />

Modific<strong>at</strong>ion <strong>of</strong> the Original Wasserman<br />

Test for Syphilis is published by Bauer in<br />

the Deutsche Medizinische Wochenschrift.<br />

The requisites <strong>of</strong> the test are, besides the<br />

serum <strong>of</strong> the suspected individual, some<br />

normal human serum; an alcohol extract<br />

<strong>of</strong> the liver <strong>of</strong> a syphilitic foetus or infant;<br />

fresh guinea-yig serum; and a suspension<br />

in saline solution <strong>of</strong> sheep's blood corpuscles.<br />

The two human sera are first he<strong>at</strong>ed<br />

to 56° C, and then four small test-tubes<br />

are prepared in the following way: One<br />

contains the p<strong>at</strong>ient's serum with five times<br />

the quantity <strong>of</strong> liver extract and <strong>of</strong> the<br />

guinea-pig serum; the second has normal<br />

saline solution substituted for liver extract,<br />

and the third and fourth resemble the first<br />

two, but contain normal instead <strong>of</strong> suspected<br />

serum. After incub<strong>at</strong>ioji <strong>at</strong> blood temper<strong>at</strong>ure<br />

for an hour the sheep's blood suspension<br />

is added to each. Hsemolysib occurs<br />

in the third and fourth, and more<br />

slowly in the second; whereas, if the p<strong>at</strong>ient<br />

is infected with syphilis, the first rube<br />

shows no haemolysis. One <strong>of</strong> the problems<br />

connected with these serological tests for<br />

syphilis is to determine precisely <strong>at</strong> wh<strong>at</strong><br />

interval after the incub<strong>at</strong>ion <strong>of</strong> the disease<br />

the serum reaction makes its appearance.<br />

On the analogy <strong>of</strong> the Widal test for typhoid<br />

fever some such l<strong>at</strong>ent period would<br />

be expected, and the point is one whose<br />

elucid<strong>at</strong>ion will be observed with interest.<br />

The claims th<strong>at</strong> have been made on behalf<br />

<strong>of</strong> the infallibility <strong>of</strong> the Wassermann reaction<br />

have been gre<strong>at</strong>, but if extended research<br />

really proves th<strong>at</strong> the method gives<br />

absolute assu.ance whether a p<strong>at</strong>ient does<br />

or does not harbour the virus <strong>of</strong> syphilis<br />

within him, it is difficult to name a more<br />

important recent bacteriological research.<br />

As yet, however, experts seem chary <strong>of</strong><br />

committing themselves quite as far as this,<br />

and rightly so until more work has been<br />

done.—The Hospital, London.<br />

Dr. Livien discusses the identific<strong>at</strong>ion <strong>of</strong><br />

the spirochseta pallida and the detection <strong>of</strong> t<br />

specific antibodies in the serum <strong>of</strong> people ^<br />

infected with syphilis. No serum therapeutic<br />

tre<strong>at</strong>ment had been found effective.<br />

Mercury and iodides remain the chief reme- i<br />

dies. He st<strong>at</strong>es th<strong>at</strong> mercury is best ad- •<br />

ministered by injection or inunction, and<br />

th<strong>at</strong> <strong>at</strong>oxyl, given in efficient doses, has<br />

proved experimentally to produce similar ;<br />

results, but is dangerous to the optic nerve.<br />

|<br />

The diagnosis should be certain before!<br />

tre<strong>at</strong>ment is started. Spirochseta should I<br />

be found, or time given for the serum-test, I<br />

or the appearance <strong>of</strong> the roseola. In most]<br />

<strong>of</strong> tne cases where ihunctions and injections f<br />

are employed local tre<strong>at</strong>ment is nnneces-ji/<br />

sary. Mercurial plaster should be used to

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