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Vol. 60, 1909 - University of North Carolina at Chapel Hill

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PHE CHARLOTTE MHDICAI. JOURNAL.<br />

eczema 1)ul other iiheiioiiiena <strong>of</strong> "exud<strong>at</strong>ive<br />

di<strong>at</strong>hesis.' 'JMiey stand the withdrawal<br />

<strong>of</strong> salt very well if it is not continued too<br />

Ions after the cur<strong>at</strong>ive effect upon the ecezenia<br />

has been noted.<br />

The Tre<strong>at</strong>ment ot Eczema ol Infants<br />

and Young Children by Thyroid.— liason<br />

(Scottish Medical and Surgical Journal)<br />

reports a series <strong>of</strong> consecutive cases <strong>of</strong> eczema<br />

in voung children successfully tre<strong>at</strong>ed<br />

bv thyroid. In the first case, fourteen<br />

months old, the baby had suffered from eczema<br />

<strong>of</strong> the face for nearly a year. This<br />

had been entirely resistant to the usual ap-<br />

plic<strong>at</strong>ions and internal tre<strong>at</strong>ment, nor was<br />

hospital tre<strong>at</strong>ment more efhcacious. Two<br />

and a half grains <strong>of</strong> a thyroid tablet was<br />

given daily. In a little more than one<br />

month the child was entirely well. His<br />

cure persisted for nearly a month, when the<br />

disease showed a tendency to recur. The<br />

second course <strong>of</strong> thyroid was followed by a<br />

permanent cure.<br />

similar results.<br />

The other cases gave<br />

Researches into the Haemoglobin Content<br />

ol Tubercular Children.— Lorenzi<br />

('La Tedi<strong>at</strong>. ) says th<strong>at</strong> (1) the number <strong>of</strong><br />

red corpuscles diminishes in proportion to<br />

the gravity <strong>of</strong> the illness and rises when an<br />

improvement in the general condition occurs.<br />

Alter<strong>at</strong>ion in form is shown by more<br />

or less marked frequency <strong>of</strong> microcytes with<br />

or without poikilocytosis. (.2) The haemoglobin<br />

content is rel<strong>at</strong>ively below the number<br />

<strong>of</strong> red corpuscles. OligochroniEemia<br />

becomes more marked with the advance <strong>of</strong><br />

the disease, and is usually more marked in<br />

the marasmus <strong>of</strong> chronic forms. It improves<br />

with the general condition. (3)<br />

The rel<strong>at</strong>ive amount <strong>of</strong> iron remains always<br />

below the correfponding amount <strong>of</strong> lieemoglobin.<br />

This inferiority is more marked<br />

when the disease is progressing, and tends<br />

to disappear, on the other hand, when the<br />

acuteness <strong>of</strong> the disease diminishes. (4)<br />

The globular value, calcul<strong>at</strong>ed with respect<br />

to iron, is always inferior to th<strong>at</strong> <strong>of</strong><br />

the haemoglobin, but their variability is not<br />

always proportion<strong>at</strong>e, although they are<br />

both in rel<strong>at</strong>ion with the course <strong>of</strong> the disease<br />

and the general st<strong>at</strong>e <strong>of</strong> the p<strong>at</strong>ient.<br />

(.5) His researches in a general way lend<br />

support to the theory <strong>of</strong> Bard with regard<br />

to vari<strong>at</strong>ions in the quality <strong>of</strong> the haemoglobin,<br />

and he is <strong>of</strong> opinion th<strong>at</strong> in infan-<br />

tile tuberculosis the alter<strong>at</strong>ions in the rela-<br />

tion <strong>of</strong> iron and haemoglobin are chiefly referable<br />

to a condition <strong>of</strong> hypohfem<strong>at</strong>opoie-<br />

The Sequelae <strong>of</strong> Scairlet Fever.—Schick<br />

(Jahrb. f. 'Kinderheilk.') discusses the<br />

following sequelae. (1) Post-scarl<strong>at</strong>iual fe<br />

ver: In the period comprised between the<br />

twelfth day and the seventh week, most<br />

frequently in the third and fourth weeks, a<br />

rise <strong>of</strong> temper<strong>at</strong>ure, usually without constitional<br />

disturbance, occurs, for which neither<br />

<strong>at</strong> the onset nor l<strong>at</strong>er is any abnormal<br />

condition <strong>of</strong> the organs to be found: il)<br />

Rheum<strong>at</strong>ism: As a rule this occurs towards<br />

the end <strong>of</strong> the first week or in the<br />

course <strong>of</strong> the second, and may be associ<strong>at</strong>ed<br />

with endocarditis, the onset <strong>of</strong> which<br />

is <strong>of</strong>ten insidious. The fever accompanying<br />

endocarditis is usually remittent, and<br />

ends by lysis. In all his cases <strong>of</strong> endocarditis<br />

the initial <strong>at</strong>tack had been mild.<br />

Rliem<strong>at</strong>ism occurring l<strong>at</strong>er than the second<br />

week is rare. He had seen only four such<br />

cases— three in the third and one in the<br />

fourth week. (3) Secondary adenitis:<br />

This may occur as an herald or as an accompaniment<br />

<strong>of</strong> nephritis and also as an<br />

indeijendent sequela. It subsides long before<br />

and is more frequent than nephritis.<br />

Nephritis and secondary adenitis do not<br />

occur before the twelfth day or laler than<br />

the sivth week, most cases being found in<br />

the third or fourth week, (4) Relapses:<br />

Schick has collected 72 cases, including l.i<br />

personal ones. Like the other sequelae <strong>of</strong><br />

scarlet fever they occur most frequently in<br />

the third or fourth week. It is doubtful<br />

whether the initial <strong>at</strong>tach find the relapse<br />

are to be <strong>at</strong>tributed to the same infection,<br />

or whether the relapse owes its origin to a<br />

fresh infection from without. He, like<br />

Hekoch, thinks th<strong>at</strong> the scarl<strong>at</strong>inal virus<br />

has not been completely elimin<strong>at</strong>ed by the<br />

primary <strong>at</strong>tack. In discussing the cause<br />

<strong>of</strong> the interval between the primary symptoms<br />

<strong>of</strong> scarlet fever and the appearance <strong>of</strong><br />

the above sequelae, he suggests th<strong>at</strong> <strong>at</strong> the<br />

usual time for the onset <strong>of</strong> sequelae the organism<br />

has a diminished power <strong>of</strong> resistance<br />

or else is super-sensitive. This period<br />

<strong>of</strong> diminished resistance or <strong>of</strong> super-.sensit<strong>at</strong>ion<br />

lasts from the end <strong>of</strong> the second<br />

week till the seventh week, and is most<br />

marked during the third and fourth weeks,<br />

after which the tendency rapidly diminishes.<br />

The hypothesis <strong>of</strong> a specific sensitiveness<br />

<strong>of</strong> the organism after scarlet fever has<br />

an analogy in other morbid processes, c. g<br />

in typhoid fever and in the serum disease.<br />

Prolonged Prlapism.-Terrier and Dujaries<br />

( Revue de Chirurgie) describe this<br />

rare affection, and collect in the medical<br />

liter<strong>at</strong>ure <strong>of</strong> the world 4S cases. This form<br />

<strong>of</strong> priapism is an erection which is not accompanied<br />

by sexual desire or by voluptuous<br />

sens<strong>at</strong>ion; on the contrary, it is frequently<br />

painful. It is never followed by<br />

ejacul<strong>at</strong>ion. In the gre<strong>at</strong>er number <strong>of</strong> cases<br />

the erection involves only the corpora cav-<br />

.

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