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Vol. 60, 1909 - University of North Carolina at Chapel Hill

Vol. 60, 1909 - University of North Carolina at Chapel Hill

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XXXir THE CHARLOTTE MEDICAL JOURNAL<br />

cases the spirochjeta should be found or nerve centers, producing a physiologic contime<br />

given for the serum test or for the ap- dition which induces n<strong>at</strong>ural sleep and repearance<br />

<strong>of</strong> a roseola. Inunctions or injec- pose.<br />

tions should then be given, in most cases no As an antipyretic it has a remarkable<br />

local tre<strong>at</strong>ment being necessary. Changres field <strong>of</strong> usefulness, inasmuch as its effecton<br />

the lips or face might be covered with iveness is not impaired by any depressing<br />

mercurial plaster; those inside the nose or tendencies. It acts, first— by increasing<br />

mouth should not be cauterized, but simply the superficial circul<strong>at</strong>ion, thus favoring<br />

dusted with nosophen or, for pain, ortho- he<strong>at</strong> radi<strong>at</strong>ion from the surface <strong>of</strong> the body,<br />

form. Secondary ulcer<strong>at</strong>ive p<strong>at</strong>ches might and second—by direct influence on the<br />

be painted with a concentr<strong>at</strong>ed solution <strong>of</strong> higher centers, especially the he<strong>at</strong> centers,<br />

chromic acid and over this a 10-per-cent. promptly controlling any elev<strong>at</strong>ion <strong>of</strong> the<br />

solution <strong>of</strong> silver nitr<strong>at</strong>e to form an adhe- temper<strong>at</strong>ure.<br />

sive scab. At the end <strong>of</strong> the first year It has valuable properties as an antipeiodides<br />

were given. After the healing <strong>of</strong> riodic and gre<strong>at</strong>ly enhances the action <strong>of</strong><br />

tertiary lesions under iodide <strong>of</strong> potassium quinine and similar remedies as a useful<br />

(the most rapid remedy ) iodipin injections synergistic.<br />

along with mercurial inunctions were use- Because <strong>of</strong> its effect on glandular strucful.—Tbe<br />

London Medical Lancet. tures, especially the liver. Phenalgin is a<br />

Pbenalgin: Its Chemistry.<br />

Among the recent triumphs <strong>of</strong> modern<br />

valuable eliminant, and this accounts for<br />

j^^ superiority over opium and its deriv<strong>at</strong>es.<br />

Moreover, no habit is ever produced by<br />

pharmaceutical chemistry Phenalgin stands Phenalgin, and it can be taken indefinitely<br />

out conspicuously as a safe, efficient and with a constant maintenance <strong>of</strong> its anodyne<br />

always reliable analgesic. It is an ammo- influence.—Canadian Journal <strong>of</strong> Medicine<br />

ni<strong>at</strong>ed coal-tar product, the result <strong>of</strong> a special<br />

process which unites the ingredients in<br />

and Surgery, July 19U9.<br />

an active form, and admits <strong>of</strong> their inde- Tre<strong>at</strong>ment <strong>of</strong> Gastralgla.<br />

pendent vet correl<strong>at</strong>ive action when taken<br />

into the body. E. Farroni says th<strong>at</strong> the causes <strong>of</strong> gas-<br />

More than ten vears <strong>of</strong> clinical experi- tralgia are numerous, and hence the tre<strong>at</strong>ence<br />

bv thousands <strong>of</strong> active practitioners ment must vary with the cause. Among<br />

all over the world has demonstr<strong>at</strong>ed th<strong>at</strong><br />

the addition <strong>of</strong> ammonia to phenylacetamide<br />

( Acetanilidumj under the conditions<br />

observed by the Etna Chemical Co., in the<br />

manufacture <strong>of</strong> Phenalgin, correct the depressing<br />

effects <strong>of</strong> the Acetanilidum to such<br />

an extent th<strong>at</strong> it becomes stimul<strong>at</strong>ing in its<br />

character, and th<strong>at</strong> though the effect <strong>of</strong> the<br />

Ammonia which is combined in the Phenalits<br />

causes are the various diseases, organic<br />

and functional, <strong>of</strong> the stomach, diseases,<br />

<strong>of</strong> the liver, kidneys, appendix, lungs, and<br />

heart. Overe<strong>at</strong>ing may cause false gastral-<br />

gia. All forms <strong>of</strong> malnutrition which result<br />

i" intoxic<strong>at</strong>ion may be added to the causes<br />

oi gastralgia. Also all the exanthem<strong>at</strong>a<br />

and infectious diseases. Hyperchlorhydria<br />

and achlorhydria may both be the cause <strong>of</strong><br />

gin is transient, it is sufficiently important pain in the stomach. External topical apto<br />

show th<strong>at</strong> Phenalgin is one <strong>of</strong> the safest pHc<strong>at</strong>ious in the form <strong>of</strong> he<strong>at</strong>, c<strong>at</strong>aplasms,<br />

andbest Analgesics, Antipyretics, and Plyp- etc., and internal hot drinks are <strong>of</strong> value,<br />

notics, ''especially valuable in Uysmenor- '^'''e introduction <strong>of</strong> the sound to relieve<br />

rhcea, " known to the medical pr<strong>of</strong>ession. distension when there is spasm <strong>of</strong> the cardia<br />

Unlike the coal-tar synthetic, Phenalgin is <strong>of</strong> considerable value in gaseous dislenis<br />

a stimulant r<strong>at</strong>her than a depressant, sion <strong>of</strong> the stomach. C^astroenterostomy<br />

To quote H<strong>of</strong>heimer— "It stimul<strong>at</strong>es the may be needed in some severe cases with<br />

pulse r<strong>at</strong>e for a short time after taking, and an<strong>at</strong>omical changes in the stomach. Acethen<br />

the heart's action gradually slows t<strong>at</strong>e <strong>of</strong> lead and nitr<strong>at</strong>e <strong>of</strong> silver are useful<br />

down with a strengthening <strong>of</strong> the first im- i" gastric ulcers which give severe pain,<br />

pulse." It is as an analgesic, however. Alkalies are to be used in hyperacidity and<br />

th<strong>at</strong> its action is most marked, and it is acids in ferment<strong>at</strong>ions due to lack <strong>of</strong> acids,<br />

without a peer in this respect. It exerts a Antiseptics are useful in the ferment<strong>at</strong>ive<br />

selective uction on sensory nerve cells, ob- cases. Sed<strong>at</strong>ives may be necessary to refunding<br />

their capacity for receiving and lieve pain and relax spasm. Farroni theretransmitting<br />

painful impressions. As has fore contends th<strong>at</strong> we do not possess any<br />

been previously outlined, Phenalgin thus specific tre<strong>at</strong>ment for gastralgia, and he<br />

prevents refiex'action in the vasomotor sys- says th<strong>at</strong> it is necessary first to diagnose the<br />

tem and removes the tendency to hypere- cause <strong>of</strong> the paiu and then to use such apmia<br />

and congestion.<br />

propri<strong>at</strong>e means <strong>of</strong> relief <strong>of</strong> the cause as the<br />

Its anodyne and hynotic influence is due practitioner may be able to apply.—Gazetta<br />

to its tranquilizing effect on the higher Medica di Roma.

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