Vol. 60, 1909 - University of North Carolina at Chapel Hill

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230 THK CHAKiÔTTK MKDiCAL JOUKNAL. ble mechanism and is ignorant of the appli- newer immunizing agents, both because o{ cation in a country practice. its more extensive and common use, and I have found that most electric charms of also because of the longer period of time clinical application are verifiable, and that over which its administration becomes necone may do sterling work out of the actual essary, I wish, though, to emphasize at beaten track indicated as practical by the this point, that what I will have to say reprofessors who instruct doctors by book garding dose graduation in tuberculin will lessons, which are mere finger boards to the be equally applicable to all biologic products," intelligent practitioner, who will advance the object of which is the increasing of tisbeyond in the strange new field of scientific sue immunity, enchantment. The plan of dosage of tuberculin quite! In the narrow sp'^ce of a medical journal universally followed is in brief as follows contribution it is impossible to do more Treatment is begun by a minimum dose, than assure practitioners that electricity is the exact amount of which depends; first, a medical necessity, if one would do some upon the condition of the patient; secondly, '-i of the best paying practice that cannot be upon the particular variety of tuberculin in dreams without the majestic current. I used. The initial dose is increased, at first, did not find it a difficult lesson; but I began very gradually, and the interval between experimenting with the old back number, the injections is comparatively short. Later almost worthless batteries, and have fol- on, larger and larger amounts of tuberculin lowed it up right along to this high degree are given with a corresponding increase of progressive epoch, where lessons are clearlj' the interval. Finally, there comes a time practical, much valuable instruction regu- when no further increase of dose can be larly appearing in current medical journal tolerated. This dose of tolerance is a most literature, written by physicians in active variable one, and depends upon many con- I practice, not by collegiate theorists, just the ditions, the details of which cannot here be aid the country doctor needs to guide him entered into. The one danger-signal to the aright. physician who is giving this powerful drug ' 1 am forty-three years in this fearful field is the reaction,—truly the "red-flag" to the of tropical fevers, in the sickliest belts of administrator of tuberculin, the Continent, without one day of vacation, that has taught me some valuable lessons To show the far-reaching harmful effects, of faulty dosage, one has only to recall the' all along the line of clinical emergencies, being still in harness beyond my four score history of the use of this same medicinal agent. Shortly following the announceyears of life; and electricity is' the future that most interests me and is my study and my desire, that absorb my else idle meditament by Koch, that he believed that in tuberculin we possessed a most valuable remedy for the treatment of tuberculosis, its tion in long rides over a broken, roadless administration was commenced by physiccountry and midnight watches beside fever- ians all over the world, with the natural ish cots; and I wish all readers hereof would and inevitable result of doing vastly more take the same interest in the grand medical harm than good. Non-selection of cases, mystery. over- dosage, and the too rapid increase of the dose given, were responsible for that Tuberculin Administration: A Perfect memorable swing of the pendulum of popu System ol Dose Gradnation. ,^^ disapproval, started by none other than By Lucius B. Morse, :\I. D., Physician-in-Charge, Virchow, the extent of which has perhaps Dr. Morse's Sanatorium, Chimney Rock, N. C. ^^^^.^^ ^^^^^ equalled itl the annals of medi- In the administration of any powerful cine. It was over fifteen years before the drug, the matter of dose is obviously an medical profession at large recovered from important one. With most of the older its over-dose of this drug. The patient and drugs the range of dosage is not very great, doctor alike experienced a reaction against and, except in rare instances, it is not nee- tuberculin. essary or desirable to gradually increase the The medical mind, however, of recent amount of any medicament given; indeed years has changed its attitude. Ourpresent the reverse almost always holds—the efforts knowledge of the nature and dosage of tuof the physician being directed toward a berculin, of its indications and contra-indidiminution, rather than an increase of dos- cations, is infinitely greater than was that age. An exception to this general rule, of those who attempted its administration though, obtains in the use of certain bio- in the early nineties. Not a few staunch logic products. I refer to the increasing believers in the value of tuberculin, though, number of such products as are given for are fearful that we are possiblv approachimmunizing purposes. ing another similar reaction against this My remarks will be limited to the use of agent;—less pronounced, perhaps, but none tuberculin as the most representative of the the less certain. It is thought, now that '
ORIGINAL COMMUNICATIONS. 231 the drug is being given by thousands of to be desired. It would also seem as though physicians, that many harmful effects will such an uneven method of administration inevitably result, particularly in the hands would certainly increase the likelihood of of those whose experience in the use of producing reactions. Now this is exactly vaccine products in general is of a very what happens. Every one who has had limited sort. experience with the use of tuberculin knows OXIM.\TE
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NORTH CAROLINA HISTORY OF HEALTH DI
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lARLOTTK MEDICAL lOURNAL. ^ SANMETT
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THE CHARLOTTE MEDICAL JOURNAL. Chat
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THE BABIES «HC thrive the best dur
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VIII THE CHARLOIVTE MEDICAL JOURNAL
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THK CHARLOTTE MEDICAL JOURNAL. MILK
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THE CHARLOTTE MEDICAL JOURNAL. NEUR
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PHF. CHARLOTTE MEDICAL JOURNAL. Atl
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AKLOTTE MKDICAL JOl'KNAL E^legant P
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THE CHARLOTTE MEDICAL JOURNAL. "We
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^^ THE CHARLOTTE MfiDICAL JOURNAL.
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' \ fth ORIGINAL COMMUNICATIONS.
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ORIGINAL COMMUNICATIONS, 5 trate ul
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ORIGINIAL COMMUNICATIONS. 7 careful
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; THE CHARLOTTE MEDICAL JOURNAL. 9
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ORIGINAL COMMUNICATIONS. 11 tuber i
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ORIGINAI, COMMCNICATIONS lo neum ab
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The chief causative factors of gast
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ORIGINAL COMMUNICATIONS. to adminis
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ease itself. The deportment of the
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ORIGINAL COMMUNICATIOXS, 21 process
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OEIGINAI. COMMUNICATIONS. 23 down t
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ORIGINAL COMMUNICATIOMS. 25 this In
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ORIGINAL OOMJIUXICATION. 27 tro-int
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ORIGIXAL COMMCNICATIONS. 29 the sam
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ORIGINAL COMMUNICATIONS. 31 tioii.
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EDITORIAL. 33 rUai'lriiio Lnai JOli
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EDITORIAL. oD Ham Jones, of High Po
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EDITORIAL. 37 Siler, of the U. S. A
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8. What is the differential diagnos
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Edgar M. Long, Hamilton. Ben F. Roy
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and H. A. Slack. "Infection and Imm
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EDITORIAI,. 45 Dr. Claude N. Smith
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I C. EDITORIAL. Association, the Am
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REVIEW OF SOUTHERN MEDICAL LITERATU
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REVIEW OF SOUTHERN- MEDICAL LITERAT
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Book Notices. The Popes and Science
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ADBVRTISEMENTS.
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INDEX FOR JULY, Table of Contents f
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ABSTRACTS Genielli, who is himself
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ADVERTISEMENTS. St. Luke's Hospital
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ADVERTISEMENTS. a mixture containin
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ADVERTISEMENTS. SOUTHERN MEDICAL SO
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»»< ADVERTISEMENTS. To obtain the
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— ADVERTISEMENTS. XXIX THE PINES,
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A most powerful non-toxic bacterici
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ADVERTISEMENTS. The Sarah Leigh Hos
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ADVERTISEMENTS. Baby needs Mellin's
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ADVERTISEMENTS. MALT WIXH REPRESENT
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^/^ ADVERTISEMENTS Aseptinol Manufa
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ADVERTISEMENTS. The State Examining
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Much better results will be obtaine
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ADVERTIESMENTS, r^mmmmmmmmmmm^mmm^m
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ADVERTISKEMTS '^he niGKSMITH HOSPIT
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VDVERTISEMEXTS ERUPTION^ Inflammati
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ADVERTISEMENTS. The Success of List
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Jlnnomicemeiit to the medical Profc
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ttiiALIH AFFAiRS LIBRARY Charlotte
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ADVERTISEMENTS. F>OST -TTPHOI RECON
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C ADVERTISEMENTS. BOVININE Reconstr
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ADVERTISEMENTS. Successfully Prescr
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ADVERTISEMENTS ^--«*»iûi4 >Ji^Wo
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\ ADVERTISEMENTS. Significant Requi
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Peak's Supporter ADVERTISEMENTS. Fo
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ADVERTISEMENTS. P0ST=0PERAT1VE CONV
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% ADVERTISEMNTS. PROFESSIONAL CARDS
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ADVERTISEMENTS. THE SPECIJIL FIELD
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IN ADVERTISEMENTS ALBUMINURIA OF BR
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The Charlotte Medical Journal Some
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for typhoid anti-bodies the destruc
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ORIGINIAI. COMMfNICATIONS. h.'l isu
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ORIGINAL COMMUNICATION. 6/ cine. I
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ORIGINAL COMMUNICATIONS. 69 membran
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ORIGINAL COMMUNICATIONS. 71 îve US
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ORIGINAL COMMUNICATIONS subject of
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ORIGINAL COMMUNICATIONS. 75 toxins.
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ORIGINAL COMMUNICATIONS, 77 tions a
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ORIGINAL COMMUNICATIONS. 79 tion or
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ORIGINAI, COMMUNICATIONS. 81 typhoi
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' first I in ' more I I been I youn
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ORIGINAL COMMUNICATIONS.
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ORIGINAL COMMUNICATIONS. .S7 Like m
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ORIGINAL COMMUNICATIONS. 89 as to t
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ORIGINAL COMMUNICATIONS. 91 as we h
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ORIGINAL COMMUNICATIONS. 93 ena sim
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effects of antitoxin treatment and
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EDITORIAL. JamesBarrinalectureon J/
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EDITORIAL. 99 logically what hither
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EDITORIAL. the father did not influ
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EDITORIAL. 103 quently they repeate
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J treatment of alcohol and drug add
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with their wives, daughters and inv
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Countv: Dr. \V. H. Ward, Plymoulli,
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REVIEW OF SOUTHERN -MEDICAL LITERAT
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Book Notices. Treatment of the Dise
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BOOK NOTICES. 119 rations and to th
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ABSTRACTS. 121 , women are subject
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ADBVETISEMENTS. The Girculatorj Dan
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. ABSTRACTS. of the rectus. This op
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INDEX FOR AUGUST. Table of Contents
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m^% ./AMENORRHEA DYSMENORRHEA -": M
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ADVERTISEMENTS. 131 THE CHARLOTTE S
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^tttmai Attest ADVERTISBMRNT3. To o
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ADVERTISHEMTS flp?!lj!uco?ie A most
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ADVERTISEMENTS. St, Luke's Hospital
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' > ' " ' ADVERTISEMENTS. >^^_ ,i&-
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I «43«« ADVERTISEMENTS. MALT IRO
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:': rflflN m WEflKEiT utih- ^ Z^flM
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ADYERTIESMEWTS, Inflammation's Anti
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This is the Food for your baby pati
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VDVERTISEMENTS ERUPTIONS Inflammati
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ADVERTISEMENTS The Success of Liste
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SOUTHERN MEDICAL SOCIETIES. MISSISS
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-'" fî-r/\jRs ÎBR/{}^Y jharlotte
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. // is a fact that ADVERTISEMENTS.
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C ADVERTISEMENTS. BOVININEI Reconst
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ADVERTISEMENTS. ^11 the tfc® Nmtur
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ADVERTISEMENTS Is pre-eminently ser
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ADVERTISEMENTS, Milk prepared with
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f ^ Peak's /^^^*=^=^\ Supporter ADV
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ADVERTISEJIENTS. BUFFALO LITHIA SPR
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ADVERTISEMNTS. I PROF ESSIONAL C AR
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Intestinal ADVERTISEMENTS. ^ '"°'"
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Oar ADVERTISEMENTS THE CHILD THAT F
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The Charlotte Medical Journal Antit
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ORIGINAI, COMMUNICATIONS. 139 tinuo
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ORIGINAL COMMUNICATIONS. 141 tiiict
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ORIGINAL COMMUNICATIONS. 143 by Shu
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ORIGINAL COMMUNICATION. 145 can be
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ORIGINAL COMMUNICATIONS. 147 Americ
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ORIGINAL COMMl'NICATIONS. 149 senti
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The reason for this is that the blo
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ORIGINAL COMMUNICATIONS. 153 chroni
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ORIGINAI, COMMUNICATION. 155 diment
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ORIGINAI. COMMUNICATIONS. 157 maind
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Charlotte Medical Journal EDITORIAL
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' attention, of the ray, and must t
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EDITORIAL. 163 one of the most sign
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165 morbidity from this disease. Ev
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North Carolina Medical College Open
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REVIEW OF SOUTHERN MEDICAL, LITERAT
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REVIEW OF SOUTHERN MEDICAI. LITERAT
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REVIEW OF SOUTHERN MEDICAI, LITERAT
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BOOK NOTICES which he lives, etc.,
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Prognosis In Tetanus.—Patton in T
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ABSTRACTS. 179 amination of every o
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ABSTRACTS. 181 Opium in the Therape
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ABSTRACTS 18,5 pleural pain, and wa
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ABSTRACTS. 185 been removed by lith
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ABSTRACT. 187 a general peritonitis
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Of the patients three were spinster
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ABSTRACTS. 191 —minimal dazzling,
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' ABSTRACTS. • 193 cellulofibrino
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ABSTRACTS. 195 George Lincoln Walto
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AD8VRTISBMBNTS. 197
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ABSTRACTS. juprarenalis. The thyroi
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TABLE OF CONTENTS FOR SEPTEMBER. Ta
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ion ceosed rather abruptly above at
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to heal the sick man as to maintain
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THE ADVERTISEMENTS. CHARLOTTE SANAT
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**< I mi ADVERTISEMENTS. To obtain
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W^mB ADVERTISEEMTS A most powerful
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UNpT. il ADVERTISEMENTS. Aseptinol
Page 333 and 334: ADVERTISEMENTS. ^^^2ZSi^^ aohannfoj
Page 335 and 336: If Interested "Êwp FOR Samples h L
Page 337 and 338: ^-MiMi^^ ADVERTIESMENTS, (Inflammat
Page 339 and 340: A physiologically correct food. A
Page 341 and 342: VDVERTISEMENTS ERUPTIONvS Inflammat
Page 343 and 344: ADVERTISEMENTS The Success of Liste
Page 345 and 346: SOUTHERN MEDICAL SOCIETIES, MISSISS
Page 347 and 348: ADVERTISEMENTS. In TREATING BRONCHI
Page 349 and 350: c ADVERTISEMENTS. BOVmiNE Reconstru
Page 351 and 352: ADVERTISEMENTS. Does not cause the
Page 353 and 354: lDVERTISEMENTS Is physiologically a
Page 355 and 356: ADVERTISEMENTS, IX PANOPEPTON Consi
Page 357 and 358: ^ Peak's \ Supporter ADVERTISEMENTS
Page 359 and 360: ADVERTISEMENTS. BUFFALO LITHIA SPRI
Page 361 and 362: —— ADVERTISEMNTS. I PROF ESSION
Page 363 and 364: Intestinal ADVERTISEMENTS. Dyspepsi
Page 365 and 366: ADVERTISEMENTS NEURASTHENIC "BREAKD
Page 367 and 368: The Charlotte Medical Journal Vol.
Page 369 and 370: ORIGINAL COMMUNICATIONS. 215 a dise
Page 371 and 372: ORIGINAL COMMUNICATIONS, 217 any of
Page 373 and 374: ORIGINAL COMMUNICATION. 2l9 accurac
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Page 377 and 378: ORIGINAL COMMUNICATIONS. 223 in spi
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Page 381 and 382: ORIGINAL CO.MMUNICATIONS. 227 branc
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Page 393 and 394: ORIGINAL COMMUNICATIONS, 239 aftern
Page 395 and 396: ORIGINIAL COMMUNICATIONS. 74 J firs
Page 397 and 398: Charlotte of t^ê Medical problem J
Page 399 and 400: works, making a total of 21n deaths
Page 401 and 402: DR. llô^^'OK COOK, DISCOVERER, lie
Page 403 and 404: EDITORIAL. 249 of a tetanic nature.
Page 405 and 406: EDITORIAL. T-< ^^:hjS^^' ->^'- - S-
Page 407 and 408: J I Board i the EDITORIAL. 253 affo
Page 409 and 410: REVIEW OF SOUTHERN MEDICAL LITERATU
Page 411 and 412: A Case ol BaclIIary Infection of th
Page 413 and 414: ABSTRACTS. indicates that a point n
Page 415 and 416: ABSTRACTS. 261 should be added thos
Page 417 and 418: ABSTRACTS. 263 sat up ill bed on th
Page 419 and 420: ABSTRACT. 7^5 sore throat that are
Page 421 and 422: ACTS 267 The Etiology ot So-Called
Page 423 and 424: nig of the spongy layer. This occur
Page 425 and 426: ABSTRACTS 271 1 It should be so adm
Page 427 and 428: AUBVKTISEMENTS. A considerable prop
Page 429 and 430: iig, immediate ligature is preferab
Page 431 and 432: TABLE OF CONTENTS FOR OCTOBER. 277
Page 433 and 434: ufactuiî, Katherine L. Storms, M.
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ABSTRACTS. Electricity in Ibe Diagn
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ADVERTISEMENTS. THE CHARLOTTE SANAT
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ADVERTISEMRNTS. B-^^'^»^BS fa For
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ADVKRTlSHK.MTS A most powerful non-
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ADVERTISEMENTS. St Luke's Hospital
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ADVERTISEMENTS. Ascftinol Manufactu
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— ADVERTISEMENTS. MALT WITH REPRE
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Ê BRIDGE BETWEEN DI6EA5E and MEALT
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ADVERTIESMENTS, HUMAN HANDS HAVE NO
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ADVERTISEMENTS. You are more assure
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VDVERTISEMENTS The First Applicatio
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SOUTHERN MEDICAL SOCIETIES, MISSISS
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'^"^^*^'^3«»v Iharlotte Medical J
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ADVERTISEMENTS. Id MEET Yhreatening
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ADVERTISEMENTS. i=[>iui;ii;ij wm Re
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ADVERTISEMENTS. Successfully Prescr
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ADVERTISEMENTS ^-Xc^xjui'sJiJ^tenoi
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THE I "I I) ADVERTISEMENTS, s Essen
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TASTELESS ADVERTISEMENTS. WHY Water
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ADVERTISEMENTS. XIII LITHIA SPRINGS
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ADVERTISEMNTS. ? :$:?: - >:?:$: - >
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t^-^-''' ADVERTISKiMENTS. >r,T-ini
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lDVERTISEMENTS THE ILLS Oh THE AGED
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; !;> The Charlotte Medical Journal
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ORIGINAL COMMUNICATIONS. 291 that a
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ORIGINAL CO.MMCNICATIONS. 203 pubii
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ORIGINAL CO^niUNICATIONS. 295 quack
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ORIGINAL COMMUNICATIONS. 297 sand o
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ORIGINAL COMMUNICATIONS. 299 stitut
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a unit work to this end and it will
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ORIGINAL COMMUNICATIONS. nobility.
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ORIGINAL COMMUNICATIONS 30S covered
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ORIGINAL COMMUNICATION. 307 of the
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, ORIGINAL COMMUNICATIONS. 309 u- i
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KDITORIAL. Charlotte Medical Journa
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EDITORIAL. 313 assumption on the ph
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EDITORIAL. 315 definite locations,
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EDITORIAL. -,jy '^ """''"' S. C.i D
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EDITORIAL. AI
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EDITORIAL. 321 EDITORIAL NEWS ITEMS
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EDITORIAL. 323 solely of addresses
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EDITORIAL. -,,r Soci^r'"'' '' ''" '
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ABSTRACTS. 397 the iiKliyidual girl
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ABSTRACTS 329 ble nurse—provided
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ABSTRACTS. ^'°" '''" ^"^' ""^'^ °
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BOOK NOTICES -,.. of Preventive Med
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ABSTRACTS. hyj,e,nc pnncples. Where
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ABSTRACTS. 337 spinal fluid of epil
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ABSTRACTS. -,^q in which, in anv ev
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ABSTRACTS. 341 then there has been
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ABSTRACTS 343 Antilormln in the Det
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I harmless. I peculiarly Calcium Sa
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ABSTRACTS. :over chancres on the li
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AUEVKTISE.MliNTS. 349 A considerabl
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REVIEW OF SOUTHERN MEDICAI, LITERAT
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TABLE OF CONTENTS FOR NOVEMI Table
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ABSTRACTS. 359 DOCTOR: OUR RESPIRAZ
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ADVERTISEMKNTS. For Upwards of Fort
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ADVERTISHEMTS A most powerful non-t
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Balttmore^Md. Pine Ridê Sanitoriii
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ADVERTISEMENTS. Bt-a—ygr-n^TT^fl
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fflflN ITi WEflKEJT UNK- IT 15 NOT
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ADVERTIESMENTS, HUMAN HANDS HAVE NO
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ADVERTISEMENTS. after circumcision
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VDVERTISEMENTS Instantaneous Is the
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SOUTHERN MEDICAL SOCIETIES. MISSISS
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Charlotte Medical Journal. A SOUTHE
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ADVERTISEMENTS. lo Meet Ihreateninc
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c ADVERTISEMENTS. BOyiNINE Reconstr
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ADVKRTISEMENTS. A.II the i« ^mdL®
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ADVERTISEMENTS DR. STEEDLY'S PRIVAT
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ADVERTISEMENTS, Fairchild's Essence
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ADVERTISEMENTS. W LgLtest Scientifi
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BUFFALO ADVERTISEMENTS. XIII ALBUMI
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ADVERTISEMNTS. I PROF ESSIONAL CARD
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OE3 ADVERTISEMENTS. I o n Quihgesim
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ADVERTISEMENTS THE ANEMIA OF BRIGHT
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j j 1 The Charlotte Medical Journal
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ORIGINAI, COMMUNICATIONS 367 diagno
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— ORIGINAL COMMUNICATIONS. 369 Dr
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ORIGINAL COMMUNICATIONS. !...v.ed I
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ORIGINAL COMMUNICATION. 373 Iter in
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ORIGINAL COMMUNICATIONS. 375 )f the
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ORIGINAL COMMUNICATIONS. 377 no occ
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ORIGINAL COMMUNICATIONS --n Û.: ra
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ORIGINAL COMMUNICATIONS. 381 ffiveh
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ORIGINAL COMMUNICATIONS. 383 i desi
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, ORIGINAL COMMUNICATIONS, ."iS.S o
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ORIGINIAL COMMUNICATIONS. .'iS? is
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EDITORIAL. .389 Charlotte ture prop
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EDITORIAL. 391 ation of information
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EDITORIAL. 393 decrease of urinary
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[ ! his I to DK. RUSSEUU MOVES TO f
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man and Dr. li. Eugene Mitchell, of
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. EDITORIAL. 3^9 J. S. Wynne, Dr. A
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EDITORIAL. 40] . ; . ellagra," Dr.
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BOOK NOTICES 405 . 1 This book is i
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ABSTRACTS. 407 ical Society, contri
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ABSTRACTS 409 Certain Bacillus Coll
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ABSTRACTS. at this Stage to check t
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Bl^tr:i:îê:S':::r^^'^:^: ;J;-Pati
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ABSTRACTS. 415 tastases and recurre
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Clinical ADEVRTISEMENTS. FUNCTIONAL
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ADVERTISEMENTS. 419 ra For Upwards
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Tblosinamlne In Deafness.— Mollis
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p was a notorious one. He not only
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TABLE OF CONTENTS FOR VOLUMI Table
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py, bv Edwin Henry 8cborer, M. !) U
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tZ^ ADVEKTISEMKNTS. A Post Graduate
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fidgetiness, especially at night. T
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I actually I ! tion i dition j I be
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ADVERTISEMENTS. DOCTOR: OUR RESPIRA
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ADVERTISEMKKTS, 4,37 A S-Pheu, form
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ADVKKTISKHMTS A most powerful non-t
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:«^ ADVERTISEMENTS. 'Ai Asepttnol
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VDVERTISEMENTS The First Applicatio
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Ir Interested Send for Smpics n LiT
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ADVIiRTIESMENTS, HUMAN HANDS HAVE N
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I 'A ADVERTISEMENTS. For your littl
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m I Sy R E P R E S E NTS THE M O ST
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Vol. 60, 1909 - University of North Carolina at Chapel Hill

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