Vol. 60, 1909 - University of North Carolina at Chapel Hill

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XXII THF CHARLOTTE MEDIOAL JOURNAL An Interesting Point in the Treatment voluntaryevacuationsof feces and urine con- i of Typboid Fever. tinned. On January 18 at noon A-S-phen i By Henry C. F. Kellner, M. D., Philadelphia, Pa., (more generally known as thermol) in five- ' Visiting Physician to the Roosevelt Hospital. g^^j,, doses every hour was added to the i One of the greatest problems that has treatment. Examination of the urine show- i confronted the medical profession in recent ed enormous numbers of typhoid bacilli S years is the discovery and proving of an present. i antithermic and antiseptic agent which will From the time of beginning the adminis- j act in typhoid fever with comparative quick- tration of A-S-phen the temperature never • ness without at the same time unduly de- rose above 101.3 degrees, the respiration i jjressing the heart action or lowering the gaii ed in depth and fell to 24 per minute, i ' i , i vitality of the organism. It would seem the duty of all the members of the profession to make accurate observations, and, from time to time, reports upon remedies and the pulse became fuller and stronger, i alihough counting at 100. The general 5 symptoms abated, and the patient slept ; quietly, with very little restlessness. On presented for their approval, in order to secure legitimate conclusion as to the merits of these drugs and compounds, with a view January 21 the temperature fell to 99, the i pulse to 94, and the respirations to 20. A ; specimen of urine sent to the laboratory j to establishing their degree of value, and showed a marked decrease in the number ! ' thus, whenever possible, adding to the arma- of typhoid bacilli. ment of the physician. The temperature diminished daily but i In a number of cases of typhoid fever gradually, a few tenths degree marking the ( occurring recently in my charge at the improvement in the averages for each day. ] Roosevelt Hospital of Philadelphia, I have With corresponding favoring changes in i been interested to note the results from the pulse and respirations, normal conditions use of a certain agent which seemed of un- were established on February 2. At this usual qualifications, and which I herewith report for comparison and investigation, The following typical cases give the salient time bacteriologic examination of the urine showed the typhoid bacillus present in very i small numbers. February 10, reports showed i features observed in administration: Case 1.— F'ritz M— , aged 26, a Russian practical elimination of the typhoid bacillus from the urine, and on February 12 the pai tailor, was admitted to the hospital January tient was discharged as cured. 1 12, 1909, with a temperature of 104 degrees. Case II.—Ethel P— , aged 22, a seam- pulse 100, respirations 24. His tongue was stress, was admitted to the hospital January badly coated, and the characteristic rose 13, 1909, with a temperature of 105 degrees, spots of typhoid fever were present on the pulse 104, respirations 24. She complained abdomen. He was given ^ sponge bath of of great malaise, and showed all the classic iced water, and the ice cap was ordered to symptoms of typhoid fever, which were conhis head. His diet was restricted to milk firmed by a positive Widal reaction and the and iced water, and a routine pepsin-hydro- determination of the presence of the bacillus chloric acid mixture was prescribed in tea- in the urine. She was placed upon a milk spoonful doses everj' three hours. diet, and a pepsin-h^'drochloric acid mix- There was the usual reduction of tern- ture reinforced by one-thirtieth grain of perature following the sponge bath, but it strychnia sulphate every three hours, was rose again to 104 degrees by noon of the ordered, with a teaspoonful or whisky. She following day, the patient lying semicon- was given a hot cleansing bath, and four | scious and restless. There was a marked hours later was sponged with iced water, loss of sphincter control, the feces and urine She made considerable complaint of pain passing involuntarily. The Widal test was in the abdomen, and some tympanites were positive. To quiet the exhausting restless- present. The bowels were ordered irrigated ness and the cephalic symptoms complained with iced water at intervals of four hours, of, the patient was given a capsule of caf- The first irrigations relumed clear, but feine citrate two grains and phenacetin five later a yellowish tinge of the water was obgrains, early in the afternoon, the dose be- served. Under this treatment the temperaing repeated at nine in the evening. Re- ture ranged from 102 to 105 degrees, with peated spongings with iced water brought full rapid pulse registering 110 and respirathe temperature down to 101 degrees dur- tions at 24. On the day of her admission a ing the next twenty-four hours. This treat- capsule of quinine sulphate two grains, ment was continued with the substitution phenacetin three grains, and salol three of one-thirtieth grain of strychnia sulphate grains, was ordered every four hours, for the plienacetin-calTeine capsule. On January 16 capsules of A-S phen, five^ From this time until January IS the tern- grain doses every two hours, were ordered perature was from 101 to 103, pulse from 95 substituted for the quinine-salol-phenacetin to 108, respiration 36, shallow. The in- combination. From this time the average '
Balttmore^Md. Pine Ridê Sanitoriiini. Banili Treat; and rulmonury '1' ADVERTISEMENTS. )f the daily temperature showed a gradual esseningof a few tenths each day, althouEh he pulse and respiraiions evinced but little uiprovement, other than a steadying of the mlse. On the ISth, the patient was given cleansing bath. Shortly after it was oticed that the fingers showed decided cy n losis at the tips, and in the fear that this ymptom might have been due to tliemedi alien employed, the use of A-Sphen was lisconlinued, and the customary pepsin fiydrochloric mixture substituted. With this hange the temperature showed a distinct ise, from lol degrees to 104, and by l
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NORTH CAROLINA HISTORY OF HEALTH DI
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lARLOTTK MEDICAL lOURNAL. ^ SANMETT
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THE CHARLOTTE MEDICAL JOURNAL. Chat
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THE BABIES «HC thrive the best dur
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VIII THE CHARLOIVTE MEDICAL JOURNAL
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THK CHARLOTTE MEDICAL JOURNAL. MILK
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THE CHARLOTTE MEDICAL JOURNAL. NEUR
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PHF. CHARLOTTE MEDICAL JOURNAL. Atl
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AKLOTTE MKDICAL JOl'KNAL E^legant P
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THE CHARLOTTE MEDICAL JOURNAL. "We
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^^ THE CHARLOTTE MfiDICAL JOURNAL.
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' \ fth ORIGINAL COMMUNICATIONS.
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ORIGINAL COMMUNICATIONS, 5 trate ul
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ORIGINIAL COMMUNICATIONS. 7 careful
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; THE CHARLOTTE MEDICAL JOURNAL. 9
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ORIGINAL COMMUNICATIONS. 11 tuber i
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ORIGINAI, COMMCNICATIONS lo neum ab
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The chief causative factors of gast
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ORIGINAL COMMUNICATIONS. to adminis
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ease itself. The deportment of the
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ORIGINAL COMMUNICATIOXS, 21 process
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OEIGINAI. COMMUNICATIONS. 23 down t
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ORIGINAL COMMUNICATIOMS. 25 this In
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ORIGINAL OOMJIUXICATION. 27 tro-int
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ORIGIXAL COMMCNICATIONS. 29 the sam
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ORIGINAL COMMUNICATIONS. 31 tioii.
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EDITORIAL. 33 rUai'lriiio Lnai JOli
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EDITORIAL. oD Ham Jones, of High Po
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EDITORIAL. 37 Siler, of the U. S. A
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8. What is the differential diagnos
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Edgar M. Long, Hamilton. Ben F. Roy
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and H. A. Slack. "Infection and Imm
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EDITORIAI,. 45 Dr. Claude N. Smith
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I C. EDITORIAL. Association, the Am
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REVIEW OF SOUTHERN MEDICAL LITERATU
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REVIEW OF SOUTHERN- MEDICAL LITERAT
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Book Notices. The Popes and Science
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ADBVRTISEMENTS.
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INDEX FOR JULY, Table of Contents f
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ABSTRACTS Genielli, who is himself
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ADVERTISEMENTS. St. Luke's Hospital
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ADVERTISEMENTS. a mixture containin
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ADVERTISEMENTS. SOUTHERN MEDICAL SO
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»»< ADVERTISEMENTS. To obtain the
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— ADVERTISEMENTS. XXIX THE PINES,
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A most powerful non-toxic bacterici
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ADVERTISEMENTS. The Sarah Leigh Hos
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ADVERTISEMENTS. Baby needs Mellin's
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ADVERTISEMENTS. MALT WIXH REPRESENT
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^/^ ADVERTISEMENTS Aseptinol Manufa
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ADVERTISEMENTS. The State Examining
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Much better results will be obtaine
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ADVERTIESMENTS, r^mmmmmmmmmmm^mmm^m
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ADVERTISKEMTS '^he niGKSMITH HOSPIT
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VDVERTISEMEXTS ERUPTION^ Inflammati
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ADVERTISEMENTS. The Success of List
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Jlnnomicemeiit to the medical Profc
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ttiiALIH AFFAiRS LIBRARY Charlotte
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ADVERTISEMENTS. F>OST -TTPHOI RECON
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C ADVERTISEMENTS. BOVININE Reconstr
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ADVERTISEMENTS. Successfully Prescr
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ADVERTISEMENTS ^--«*»iûi4 >Ji^Wo
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\ ADVERTISEMENTS. Significant Requi
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Peak's Supporter ADVERTISEMENTS. Fo
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ADVERTISEMENTS. P0ST=0PERAT1VE CONV
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% ADVERTISEMNTS. PROFESSIONAL CARDS
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ADVERTISEMENTS. THE SPECIJIL FIELD
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IN ADVERTISEMENTS ALBUMINURIA OF BR
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The Charlotte Medical Journal Some
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for typhoid anti-bodies the destruc
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ORIGINIAI. COMMfNICATIONS. h.'l isu
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ORIGINAL COMMUNICATION. 6/ cine. I
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ORIGINAL COMMUNICATIONS. 69 membran
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ORIGINAL COMMUNICATIONS. 71 îve US
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ORIGINAL COMMUNICATIONS subject of
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ORIGINAL COMMUNICATIONS. 75 toxins.
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ORIGINAL COMMUNICATIONS, 77 tions a
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ORIGINAL COMMUNICATIONS. 79 tion or
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ORIGINAI, COMMUNICATIONS. 81 typhoi
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' first I in ' more I I been I youn
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ORIGINAL COMMUNICATIONS.
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ORIGINAL COMMUNICATIONS. .S7 Like m
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ORIGINAL COMMUNICATIONS. 89 as to t
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ORIGINAL COMMUNICATIONS. 91 as we h
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ORIGINAL COMMUNICATIONS. 93 ena sim
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effects of antitoxin treatment and
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EDITORIAL. JamesBarrinalectureon J/
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EDITORIAL. 99 logically what hither
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EDITORIAL. the father did not influ
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EDITORIAL. 103 quently they repeate
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J treatment of alcohol and drug add
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with their wives, daughters and inv
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Countv: Dr. \V. H. Ward, Plymoulli,
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REVIEW OF SOUTHERN -MEDICAL LITERAT
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Book Notices. Treatment of the Dise
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BOOK NOTICES. 119 rations and to th
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ABSTRACTS. 121 , women are subject
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ADBVETISEMENTS. The Girculatorj Dan
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. ABSTRACTS. of the rectus. This op
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INDEX FOR AUGUST. Table of Contents
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m^% ./AMENORRHEA DYSMENORRHEA -": M
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ADVERTISEMENTS. 131 THE CHARLOTTE S
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^tttmai Attest ADVERTISBMRNT3. To o
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ADVERTISHEMTS flp?!lj!uco?ie A most
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ADVERTISEMENTS. St, Luke's Hospital
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' > ' " ' ADVERTISEMENTS. >^^_ ,i&-
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I «43«« ADVERTISEMENTS. MALT IRO
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:': rflflN m WEflKEiT utih- ^ Z^flM
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ADYERTIESMEWTS, Inflammation's Anti
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This is the Food for your baby pati
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VDVERTISEMENTS ERUPTIONS Inflammati
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ADVERTISEMENTS The Success of Liste
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SOUTHERN MEDICAL SOCIETIES. MISSISS
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-'" fî-r/\jRs ÎBR/{}^Y jharlotte
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. // is a fact that ADVERTISEMENTS.
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C ADVERTISEMENTS. BOVININEI Reconst
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ADVERTISEMENTS. ^11 the tfc® Nmtur
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ADVERTISEMENTS Is pre-eminently ser
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ADVERTISEMENTS, Milk prepared with
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f ^ Peak's /^^^*=^=^\ Supporter ADV
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ADVERTISEJIENTS. BUFFALO LITHIA SPR
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ADVERTISEMNTS. I PROF ESSIONAL C AR
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Intestinal ADVERTISEMENTS. ^ '"°'"
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Oar ADVERTISEMENTS THE CHILD THAT F
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The Charlotte Medical Journal Antit
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ORIGINAI, COMMUNICATIONS. 139 tinuo
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ORIGINAL COMMUNICATIONS. 141 tiiict
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ORIGINAL COMMUNICATIONS. 143 by Shu
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ORIGINAL COMMUNICATION. 145 can be
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ORIGINAL COMMUNICATIONS. 147 Americ
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ORIGINAL COMMl'NICATIONS. 149 senti
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The reason for this is that the blo
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ORIGINAL COMMUNICATIONS. 153 chroni
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ORIGINAI, COMMUNICATION. 155 diment
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ORIGINAI. COMMUNICATIONS. 157 maind
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Charlotte Medical Journal EDITORIAL
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' attention, of the ray, and must t
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EDITORIAL. 163 one of the most sign
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165 morbidity from this disease. Ev
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North Carolina Medical College Open
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REVIEW OF SOUTHERN MEDICAL, LITERAT
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REVIEW OF SOUTHERN MEDICAI. LITERAT
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REVIEW OF SOUTHERN MEDICAI, LITERAT
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BOOK NOTICES which he lives, etc.,
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Prognosis In Tetanus.—Patton in T
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ABSTRACTS. 179 amination of every o
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ABSTRACTS. 181 Opium in the Therape
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ABSTRACTS 18,5 pleural pain, and wa
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ABSTRACTS. 185 been removed by lith
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ABSTRACT. 187 a general peritonitis
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Of the patients three were spinster
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ABSTRACTS. 191 —minimal dazzling,
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' ABSTRACTS. • 193 cellulofibrino
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ABSTRACTS. 195 George Lincoln Walto
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AD8VRTISBMBNTS. 197
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ABSTRACTS. juprarenalis. The thyroi
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TABLE OF CONTENTS FOR SEPTEMBER. Ta
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ion ceosed rather abruptly above at
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to heal the sick man as to maintain
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THE ADVERTISEMENTS. CHARLOTTE SANAT
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**< I mi ADVERTISEMENTS. To obtain
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W^mB ADVERTISEEMTS A most powerful
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UNpT. il ADVERTISEMENTS. Aseptinol
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ADVERTISEMENTS. ^^^2ZSi^^ aohannfoj
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If Interested "Êwp FOR Samples h L
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^-MiMi^^ ADVERTIESMENTS, (Inflammat
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A physiologically correct food. A
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VDVERTISEMENTS ERUPTIONvS Inflammat
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SOUTHERN MEDICAL SOCIETIES, MISSISS
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ADVERTISEMENTS. In TREATING BRONCHI
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c ADVERTISEMENTS. BOVmiNE Reconstru
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ADVERTISEMENTS. Does not cause the
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lDVERTISEMENTS Is physiologically a
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ADVERTISEMENTS, IX PANOPEPTON Consi
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^ Peak's \ Supporter ADVERTISEMENTS
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ADVERTISEMENTS. BUFFALO LITHIA SPRI
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—— ADVERTISEMNTS. I PROF ESSION
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Intestinal ADVERTISEMENTS. Dyspepsi
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ADVERTISEMENTS NEURASTHENIC "BREAKD
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The Charlotte Medical Journal Vol.
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ORIGINAL COMMUNICATIONS. 215 a dise
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ORIGINAL COMMUNICATIONS, 217 any of
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ORIGINAL COMMUNICATION. 2l9 accurac
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ORIGINIAL COMMUNICATIONS. 221 of an
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ORIGINAL COMMUNICATIONS. 223 in spi
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ORIGINAL COMMUNICATIONS. 225 i the
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ORIGINAL CO.MMUNICATIONS. 227 branc
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ORIGINAL COMMUNICATIONS. 229 where
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ORIGINAL COMMUNICATIONS. 231 the dr
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1 fraction ORIGINAL COMMUNICATIONS.
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ORIGINAL COMMUNICATIONS. 235 But th
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. ORIGINAL COMMUNICATIONS. ant ones
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ORIGINAL COMMUNICATIONS, 239 aftern
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ORIGINIAL COMMUNICATIONS. 74 J firs
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Charlotte of t^ê Medical problem J
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works, making a total of 21n deaths
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DR. llô^^'OK COOK, DISCOVERER, lie
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EDITORIAL. 249 of a tetanic nature.
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EDITORIAL. T-< ^^:hjS^^' ->^'- - S-
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J I Board i the EDITORIAL. 253 affo
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A Case ol BaclIIary Infection of th
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ABSTRACTS. indicates that a point n
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ABSTRACTS. 261 should be added thos
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ABSTRACTS. 263 sat up ill bed on th
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ABSTRACT. 7^5 sore throat that are
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ACTS 267 The Etiology ot So-Called
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nig of the spongy layer. This occur
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ABSTRACTS 271 1 It should be so adm
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AUBVKTISEMENTS. A considerable prop
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iig, immediate ligature is preferab
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TABLE OF CONTENTS FOR OCTOBER. 277
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ufactuiî, Katherine L. Storms, M.
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ABSTRACTS. Electricity in Ibe Diagn
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ADVERTISEMENTS. THE CHARLOTTE SANAT
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ADVERTISEMRNTS. B-^^'^»^BS fa For
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ADVKRTlSHK.MTS A most powerful non-
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ADVERTISEMENTS. St Luke's Hospital
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ADVERTISEMENTS. Ascftinol Manufactu
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— ADVERTISEMENTS. MALT WITH REPRE
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Ê BRIDGE BETWEEN DI6EA5E and MEALT
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ADVERTIESMENTS, HUMAN HANDS HAVE NO
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ADVERTISEMENTS. You are more assure
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VDVERTISEMENTS The First Applicatio
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SOUTHERN MEDICAL SOCIETIES, MISSISS
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'^"^^*^'^3«»v Iharlotte Medical J
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ADVERTISEMENTS. Id MEET Yhreatening
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ADVERTISEMENTS. i=[>iui;ii;ij wm Re
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ADVERTISEMENTS. Successfully Prescr
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ADVERTISEMENTS ^-Xc^xjui'sJiJ^tenoi
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THE I "I I) ADVERTISEMENTS, s Essen
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TASTELESS ADVERTISEMENTS. WHY Water
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ADVERTISEMENTS. XIII LITHIA SPRINGS
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ADVERTISEMNTS. ? :$:?: - >:?:$: - >
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t^-^-''' ADVERTISKiMENTS. >r,T-ini
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lDVERTISEMENTS THE ILLS Oh THE AGED
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; !;> The Charlotte Medical Journal
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ORIGINAL COMMUNICATIONS. 291 that a
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ORIGINAL CO.MMCNICATIONS. 203 pubii
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ORIGINAL CO^niUNICATIONS. 295 quack
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ORIGINAL COMMUNICATIONS. 297 sand o
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ORIGINAL COMMUNICATIONS. 299 stitut
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a unit work to this end and it will
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ORIGINAL COMMUNICATIONS. nobility.
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ORIGINAL COMMUNICATIONS 30S covered
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ORIGINAL COMMUNICATION. 307 of the
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, ORIGINAL COMMUNICATIONS. 309 u- i
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KDITORIAL. Charlotte Medical Journa
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EDITORIAL. 313 assumption on the ph
Page 511 and 512: EDITORIAL. 315 definite locations,
Page 513 and 514: EDITORIAL. -,jy '^ """''"' S. C.i D
Page 515 and 516: EDITORIAL. AI
Page 517 and 518: EDITORIAL. 321 EDITORIAL NEWS ITEMS
Page 519 and 520: EDITORIAL. 323 solely of addresses
Page 521 and 522: EDITORIAL. -,,r Soci^r'"'' '' ''" '
Page 523 and 524: ABSTRACTS. 397 the iiKliyidual girl
Page 525 and 526: ABSTRACTS 329 ble nurse—provided
Page 527 and 528: ABSTRACTS. ^'°" '''" ^"^' ""^'^ °
Page 529 and 530: BOOK NOTICES -,.. of Preventive Med
Page 531 and 532: ABSTRACTS. hyj,e,nc pnncples. Where
Page 533 and 534: ABSTRACTS. 337 spinal fluid of epil
Page 535 and 536: ABSTRACTS. -,^q in which, in anv ev
Page 537 and 538: ABSTRACTS. 341 then there has been
Page 539 and 540: ABSTRACTS 343 Antilormln in the Det
Page 541 and 542: I harmless. I peculiarly Calcium Sa
Page 543 and 544: ABSTRACTS. :over chancres on the li
Page 545 and 546: AUEVKTISE.MliNTS. 349 A considerabl
Page 547 and 548: REVIEW OF SOUTHERN MEDICAI, LITERAT
Page 549 and 550: TABLE OF CONTENTS FOR NOVEMI Table
Page 551 and 552: REVIEW OF SOUTHERN MEDICAL LITERATU
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Page 555 and 556: ABSTRACTS. 359 DOCTOR: OUR RESPIRAZ
Page 557 and 558: ADVERTISEMKNTS. For Upwards of Fort
Page 559 and 560: ADVERTISHEMTS A most powerful non-t
Page 561: ADVERTISEMENTS. St. Luke's Hospital
Page 565 and 566: ADVERTISEMENTS. Bt-a—ygr-n^TT^fl
Page 567 and 568: fflflN ITi WEflKEJT UNK- IT 15 NOT
Page 569 and 570: ADVERTIESMENTS, HUMAN HANDS HAVE NO
Page 571 and 572: ADVERTISEMENTS. after circumcision
Page 573 and 574: VDVERTISEMENTS Instantaneous Is the
Page 575 and 576: ADVERTISEMENTS The Success of Liste
Page 577 and 578: SOUTHERN MEDICAL SOCIETIES. MISSISS
Page 579 and 580: Charlotte Medical Journal. A SOUTHE
Page 581 and 582: ADVERTISEMENTS. lo Meet Ihreateninc
Page 583 and 584: c ADVERTISEMENTS. BOyiNINE Reconstr
Page 585 and 586: ADVKRTISEMENTS. A.II the i« ^mdL®
Page 587 and 588: ADVERTISEMENTS DR. STEEDLY'S PRIVAT
Page 589 and 590: ADVERTISEMENTS, Fairchild's Essence
Page 591 and 592: ADVERTISEMENTS. W LgLtest Scientifi
Page 593 and 594: BUFFALO ADVERTISEMENTS. XIII ALBUMI
Page 595 and 596: ADVERTISEMNTS. I PROF ESSIONAL CARD
Page 597 and 598: OE3 ADVERTISEMENTS. I o n Quihgesim
Page 599 and 600: ADVERTISEMENTS THE ANEMIA OF BRIGHT
Page 601 and 602: j j 1 The Charlotte Medical Journal
Page 603 and 604: ORIGINAI, COMMUNICATIONS 367 diagno
Page 605 and 606: — ORIGINAL COMMUNICATIONS. 369 Dr
Page 607 and 608: ORIGINAL COMMUNICATIONS. !...v.ed I
Page 609 and 610: ORIGINAL COMMUNICATION. 373 Iter in
Page 611 and 612: ORIGINAL COMMUNICATIONS. 375 )f the
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ORIGINAL COMMUNICATIONS. 377 no occ
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ORIGINAL COMMUNICATIONS --n Û.: ra
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ORIGINAL COMMUNICATIONS. 381 ffiveh
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ORIGINAL COMMUNICATIONS. 383 i desi
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, ORIGINAL COMMUNICATIONS, ."iS.S o
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ORIGINIAL COMMUNICATIONS. .'iS? is
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EDITORIAL. .389 Charlotte ture prop
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EDITORIAL. 391 ation of information
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EDITORIAL. 393 decrease of urinary
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[ ! his I to DK. RUSSEUU MOVES TO f
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man and Dr. li. Eugene Mitchell, of
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. EDITORIAL. 3^9 J. S. Wynne, Dr. A
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EDITORIAL. 40] . ; . ellagra," Dr.
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BOOK NOTICES 405 . 1 This book is i
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ABSTRACTS. 407 ical Society, contri
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ABSTRACTS 409 Certain Bacillus Coll
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ABSTRACTS. at this Stage to check t
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Bl^tr:i:îê:S':::r^^'^:^: ;J;-Pati
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ABSTRACTS. 415 tastases and recurre
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Clinical ADEVRTISEMENTS. FUNCTIONAL
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ADVERTISEMENTS. 419 ra For Upwards
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Tblosinamlne In Deafness.— Mollis
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p was a notorious one. He not only
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TABLE OF CONTENTS FOR VOLUMI Table
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py, bv Edwin Henry 8cborer, M. !) U
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tZ^ ADVEKTISEMKNTS. A Post Graduate
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fidgetiness, especially at night. T
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I actually I ! tion i dition j I be
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ADVERTISEMENTS. DOCTOR: OUR RESPIRA
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ADVERTISEMKKTS, 4,37 A S-Pheu, form
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ADVKKTISKHMTS A most powerful non-t
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:«^ ADVERTISEMENTS. 'Ai Asepttnol
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VDVERTISEMENTS The First Applicatio
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Ir Interested Send for Smpics n LiT
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ADVIiRTIESMENTS, HUMAN HANDS HAVE N
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I 'A ADVERTISEMENTS. For your littl
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m I Sy R E P R E S E NTS THE M O ST
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Vol. 60, 1909 - University of North Carolina at Chapel Hill

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