Catalogue of Research Groups from Moldova - WBC-INCO Net
Catalogue of Research Groups from Moldova - WBC-INCO Net
Catalogue of Research Groups from Moldova - WBC-INCO Net
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SEVENTH FRAMEWORK<br />
PROGRAMME<br />
THE LABORATORY OF MICROBIOLOGY & MORPHOLOGY OF TUBERCULOSIS<br />
Organization activity type : RES<br />
FP7 theme : hEalTh<br />
Contact person : Dr. Valeriu Crudu<br />
Address : The Institute <strong>of</strong> Phthisiopneumology “Chiril Draganiuc”<br />
13, Virnav street<br />
MD 2025, Chisinau<br />
Republic <strong>of</strong> <strong>Moldova</strong><br />
E-mail : valeriu.crudu@gmail.com<br />
Web : www.ifp.asm.md<br />
THE INSTITUTE OF PHTHISIOPNEUMOLOGY “CHIRIL DRAGANIUC”<br />
BRIEf dESCRIpTIon <strong>of</strong> ThE oRganIzaTIon<br />
The Laboratory <strong>of</strong> Microbiology & Morphology <strong>of</strong> Tuberculosis(TB) functions as the coordinating<br />
body for the microbiological TB diagnosis services.<br />
The laboratory performs microscopic investigations; isolations <strong>of</strong> pure M. tuberculosis cultures;<br />
epidemiological surveys <strong>of</strong> anti-TB drug resistance; molecular line probe assays for rapid screening <strong>of</strong><br />
patients at risk <strong>of</strong> multidrug-resistant tuberculosis (MDR-TB).<br />
The Laboratory is equipped with biosafety cabinets, autoclaves, BACTEC/MGIT, thermostats, PCR<br />
machines, equipment for genetic identifications <strong>of</strong> Mycobacteria, and fluorescent microscopes.<br />
Staff <strong>of</strong> laboratory 10 : 5 MD (including 2 PhD), 5 lab technicians.<br />
KEywoRdS on CoRE CompETEnCIES<br />
Mycobacteria; tuberculosis; drug resistance; MDR TB; molecular LiPA.<br />
ExpERTISE / CompETEnCIES / TEChnologIES / RTd Know-how<br />
Molecular line probe assays; isolation <strong>of</strong> pure cultures <strong>of</strong> M.tuberculosis (classic LJ method, BACTEC<br />
MGIT); fluorescence microscopy investigations; epidemiological survey <strong>of</strong> anti-TB drug resistance.<br />
InTERnaTIonal CoopERaTIon ExpERIEnCE<br />
The laboratory participates in a few international projects :<br />
• Rapid Tests for Drug Resistance to Detect Extensively Drug-Resistant Tuberculosis. DMID Protocol Number :<br />
09-0099. Sponsored by : National Institute <strong>of</strong> Allergy and Infectious Diseases (NIAID). DMID Funding Mechanism<br />
: Cooperative <strong>Research</strong> Partnerships for Biodefense and Emerging Diseases. Principal Investigator : Antonino<br />
Catanzaro; University <strong>of</strong> California, San Diego.<br />
• TB PAN-NET : Pan-European network for study and clinical management <strong>of</strong> drug resistant tuberculosis. “Clinical<br />
research drug resistant TB in Europe” TBPANNET is a European collaboration for research on MDR/XDR-TB,<br />
which has the task to establish a European data base on MDR-TB. <strong>Research</strong> Centre Borstel and TBNET are the<br />
administrative and implementing partners in this project.<br />
• Project : ”Evaluation <strong>of</strong> the ß Version <strong>of</strong> the Genotype® Mtbresdir Test with Nalc-Decontaminated Clinical<br />
Specimens”. Study coordinator : Dr. Vera Allerheiligen, Hain Lifescience GmbH. Function <strong>of</strong> the ß version <strong>of</strong> the<br />
GenoType® MTBResDir test . The ß version <strong>of</strong> the „GenoType® MTBResDir” test is a molecular-genetic test system<br />
for the identification <strong>of</strong> the Mycobacterium tuberculosis complex (MTBC) and its resistance against rifampicin and/<br />
or isoniazid <strong>from</strong> culture samples and specimens.<br />
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