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Catalogue of Research Groups from Moldova - WBC-INCO Net

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SEVENTH FRAMEWORK<br />

PROGRAMME<br />

THE LABORATORY OF HUMAN REPRODUCTION AND IMMUNOCHEMICAL<br />

INVESTIGATIONS<br />

Organization activity type : RES<br />

FP7 theme : hEalTh<br />

Contact person : Dr. Natalia Sorici<br />

Address : National Centre <strong>of</strong> Reproductive Health and Medical Genetics<br />

82 Burebista street<br />

MD 2062, Chisinau<br />

Republic <strong>of</strong> <strong>Moldova</strong><br />

E-mail : nsorici@yahoo.com<br />

Web : www.reprogenetics.md<br />

NATIONAL CENTRE OF REPRODUCTIVE HEALTH AND MEDICAL GENETICS<br />

BRIEf dESCRIpTIon <strong>of</strong> ThE oRganIzaTIon<br />

The Laboratory has determined significant immune disorders in the peritoneal fluid <strong>of</strong> women with<br />

tubo-peritoneal sterility : T-cellular-immunodeficiency, disorder <strong>of</strong> the psychological immunoregulatory<br />

balance; B-lymphocytosis; decreasins <strong>of</strong> phagocytary activity <strong>of</strong> neutrophiles (segmented cells);<br />

presence and increasing <strong>of</strong> C-reactive proteins’s concentration decreasing the number <strong>of</strong> macrophages<br />

and macrophagic activity and interleukines IL-1ß and IL-6.<br />

The number <strong>of</strong> peritoneal macrophages corresponds to macrophagic activity. The Laboratory developed<br />

algorithm to optimise the diagnostic and patients with tubal infertility, assisted reproduction program<br />

includes.<br />

KEywoRdS on CoRE CompETEnCIES<br />

Infertility; reproduction; FIV; obstetric; gynaecology.<br />

ExpERTISE / CompETEnCIES / TEChnologIES / RTd Know-how<br />

IVF treatment; diagnostic ultrasound.<br />

InTERnaTIonal CoopERaTIon ExpERIEnCE<br />

The Laboratory is implementing a bilateral <strong>Moldova</strong>n-Romanian project “Diagnostics <strong>of</strong> molecular and<br />

proteomic implications in microbial cause <strong>of</strong> infertility - acronym : infertmic (2010-2012)”.<br />

Expected results at the end <strong>of</strong> the project : • elaboration <strong>of</strong> standards and protocols to guide basic<br />

and applied research <strong>of</strong> tubo-peritoneal infertility. • 2 articles will be published in journals indexed in<br />

international databases.<br />

48

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