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Nahar (2004)
(-)/(-)
Tukur (2007)
(+)/(-)
Women with
eclampsia or preeclampsia
Women with
antepartum
eclampsia
Micronutrient supplementation
Fawzi (2007)
(++)/(++)
HIV-negative
pregnant women
Misoprostol in severe pre-eclampsia (group
1) and eclampsia patients(group 2) with
unripe cervix. 50mg of misoprostol was
used every 4 hours in cases of unripe cervix
(Bishop score < or = 6). Magnesium sulphate
was used routinely for patients with
eclampsia.
Misoprostol. If the patient did not go into
labour within four hours of inserting
misoprostol, the induction was considered
to have failed and emergency CS offered.
CS was also offered if any other
complication that warranted a CS such as
foetal distress arose.
Daily multivitamins vs placebo (all women
received iron and folic acid supplements).
Maternal
mortality
Perinatal
mortality
Maternal
mortality
Perinatal
mortality
Perinatal
mortality
Neonatal
mortality
Appendix 4.1
The groups were compared to each
other but no control so impact on
mortality not clear. No maternal deaths
recorded. Neonatal deaths were 11% in
severe pre-eclampsia group and 12% in
eclampsia group. Study concludes that
intravaginal misoprostol is well
tolerated and very effective for the
induction of labour in severe preeclampsia
and eclampsia patients with
unripe cervix.
There were more maternal
complications and admissions of babies
into the neonatal special care unit
(NSCU) in the CS group compared to
misoprostol group. Maternal mortality in
the two groups was similar (2% each).
HIV-negative Tanzanian women who
received prenatal supplementation with
vitamin B complex and vitamins C and E
did not have significantly reduced risks
of prematurity and foetal death, but
they did have significantly reduced risk
of LBW.
What are the effects of different models of delivery for improving maternal and infant health outcomes for poor people in urban areas in low income
and lower middle income countries?
199