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Full Report - Research for Development - Department for ...

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Appendix 4.2: Included items dealing with clinical interventions and infant mortality<br />

Author<br />

(year)<br />

(IV)/(EV)<br />

Target<br />

Population<br />

Surgical/instrumental procedures<br />

Ziadeh<br />

(2000)<br />

(-)/(-)<br />

Brief intervention description Targeted<br />

outcome(s)<br />

Triplets Caesarean section. Perinatal<br />

mortality<br />

Drug treatment (including micronutrient supplementation)<br />

Cobra<br />

(1997)<br />

(++)/(++)<br />

de Long<br />

(1997)<br />

(+)/(+)<br />

Infants in<br />

general<br />

Women in<br />

general<br />

Neonates in<br />

general<br />

Infants in<br />

general<br />

Oral iodized oil (100 mg) administered at<br />

around 6 weeks of age and infants followed<br />

to 6 months of age.<br />

Potassium iodate added to irrigation water<br />

over a 2 to 4 week period.<br />

Infant<br />

mortality<br />

Neonatal<br />

mortality<br />

Infant<br />

mortality<br />

Findings summary<br />

Appendix 4.2<br />

Caesarean section not advantageous.<br />

Perinatal mortality was greater among Csection<br />

group but very small sample size.<br />

Reduction in mortality in the iodized oil<br />

group during the first 2 months of follow-up<br />

and a delay in the mean time to death<br />

among infants who died in the iodized oil<br />

group compared with infants who died in<br />

the placebo group.<br />

Infant mortality rates decreased in the<br />

treated areas. Similar results were seen <strong>for</strong><br />

neonatal mortality.<br />

What are the effects of different models of delivery <strong>for</strong> improving maternal and infant health outcomes <strong>for</strong> poor people in urban areas in low income<br />

and lower middle income countries?<br />

208

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