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Full Report - Research for Development - Department for ...

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Kaestel<br />

(2005)<br />

(++)/(++)<br />

Kupka<br />

(2008)<br />

(++)/(-)<br />

Anthelmintics<br />

de Silva<br />

(1999)<br />

(+)/(++)<br />

Pregnant women Daily micronutrient supplementation in<br />

Guinea-Bissau. Identical capsules – group 1<br />

with one RDA of 15 micronutrients, group 2<br />

with two RDA of 15 micronutrients, group 3<br />

conventional prenatal iron-folic acid<br />

supplement.<br />

HIV-infected<br />

pregnant women<br />

Selenium supplementation – daily tablet of<br />

200ug elemental selenium (as<br />

selenomethionine).<br />

Women in general Mebendazole during pregnancy vs no<br />

anthelmintic (controls).<br />

Perinatal<br />

mortality<br />

Neonatal<br />

mortality<br />

Maternal<br />

mortality<br />

Perinatal<br />

mortality<br />

Neonatal<br />

mortality<br />

Infant<br />

mortality<br />

Stillbirth<br />

Perinatal<br />

mortality<br />

Appendix 4.1<br />

There were no overall differences in<br />

either peri- or neonatal mortality<br />

between supplementation groups and<br />

the control group. There was no effect<br />

modification by anaemia, malaria<br />

parasitaemia, infant sex, or season of<br />

birth.<br />

Selenium had no significant effect on<br />

maternal mortality, neonatal or infant<br />

mortality. Marginal association with<br />

reduced risk of low birthweight (LBW)<br />

and increased risk of foetal death.<br />

The proportions of stillbirths and<br />

perinatal deaths were significantly<br />

lower in the mebendazole group, as was<br />

the proportion of LBW babies.<br />

What are the effects of different models of delivery <strong>for</strong> improving maternal and infant health outcomes <strong>for</strong> poor people in urban areas in low income<br />

and lower middle income countries?<br />

200

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