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Full Report - Research for Development - Department for ...

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Author<br />

(year)<br />

(IV)/(EV) and<br />

settings<br />

Le Fevre<br />

(2010)<br />

(++)/(+)<br />

Bangladesh<br />

Intervention<br />

(I) and<br />

comparator<br />

(C)<br />

I: Topical<br />

emollients –<br />

synthetic<br />

Aquaphor or<br />

sunflower<br />

seed oil<br />

C: No<br />

treatment<br />

Target<br />

population<br />

and duration<br />

of economic<br />

analysis<br />

497 low<br />

birthweight<br />

babies <<br />

1,500 g. Preterm<br />

infants<br />

only receiving<br />

hospital care<br />

within 72<br />

hours of<br />

birth.<br />

28 days<br />

Study<br />

design<br />

RCT<br />

CEA<br />

Cost results Mortality-related<br />

effectiveness results<br />

Annualised total<br />

intervention<br />

costs <strong>for</strong><br />

programme,<br />

including startup<br />

costs<br />

US$1,834.<br />

Average cost<br />

per patient in<br />

Aquaphor, SSO<br />

and No<br />

treatment<br />

groups were<br />

$125.35, $99.47<br />

and $93.39<br />

respectively. P<br />

values not<br />

reported.<br />

26% reduction in<br />

mortality with SSO<br />

compared to no<br />

treatment; or 523<br />

years of life lost (YLL)<br />

averted.<br />

32% reduction in<br />

mortality with<br />

Aquaphor compared to<br />

no treatment; or 649<br />

YLL averted.<br />

Perspective/price<br />

year<br />

Health sector<br />

costs, including<br />

start-up costs<br />

US$ 2006 prices<br />

Appendix 4.8<br />

Synthesis of<br />

costs and<br />

effectiveness<br />

data<br />

For SSO,<br />

incremental cost<br />

compared to no<br />

treatment of US$<br />

61 per death<br />

averted or $2.15<br />

per YLL averted.<br />

For Aquaphor<br />

incremental cost<br />

compared to no<br />

treatment of US$<br />

162 per death<br />

averted or $5.74<br />

per YLL averted.<br />

What are the effects of different models of delivery <strong>for</strong> improving maternal and infant health outcomes <strong>for</strong> poor people in urban areas in low income<br />

and lower middle income countries?<br />

235

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