Full Report - Research for Development - Department for ...

Author
(year)
(IV)/(EV)
Malaba
2005
(++)/(++)
Miller
(1994)
(+)/(++)
Vaccinations
Aaby
(2002)
(+)/(+)
Target
Population
Neonates born
to HIV negative
mothers
Infants in
general
Children up to
20 months in a
war situation
Brief intervention description Targeted
outcome(s)
A single large dose of vitamin A during the
immediate postpartum period. Infants were
randomly assigned to 1 of 4 treatment
groups: mothers and infants received vitamin
A (Aa), mothers received vitamin A and
infants received placebo (Ap), mothers
received placebo and infants received
vitamin A (Pa), and both mothers and infants
received placebo (Pp). The vitamin A dose in
the mothers was 400,000 IU and in the infants
was 50,000 IU. The mother-infant pairs were
followed to 12 months.
Infant
mortality
Widened availability of ORS Infant
mortality
Diphtheria, tetanus, pertussis (DTP); polio
vaccines; and measles vaccines.
Infant
mortality
Findings summary
Appendix 4.2
No significant effect in any of the
intervention groups compared with the
control group receiving a placebo.
Improvement in case management and
mortality decline following increased ORS
availability.
Measles-vaccinated children had lower
mortality than measles non-vaccinated
children, but the difference was more
marked for girls. The reduction was
unrelated to prevention against measles
infection. DTP and polio-vaccinated
children did not have lower mortality than
non-vaccinated children.
What are the effects of different models of delivery for improving maternal and infant health outcomes for poor people in urban areas in low income
and lower middle income countries?
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