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Author
(year)
(IV)/(EV) and
settings
Sharieff
(2008)
(+)/(-)
Pakistan
Intervention
(I) and
comparator
(C)
I: Nutritional
supplement
containing
iron and zinc
in form of
sprinkles
C: Placebo
product
Target
population
and duration
of economic
analysis
Hypothetical
cohort of
5,000 6-12
month infants
Effectiveness
data from
two RCTs
Resource use
data from
Pakistan
Sprinkles
Diarrhoea
study
Study
design
Modelling
study
CBA
Modelled
outcomes
until age
55
Cost results Mortality-related
effectiveness results
Net cost per
child was $10 –
$473 in the
Sprinkles group
and $1.31–$512
in the placebo
group.
Based on data in
effectiveness studies,
estimated risk ratio in
mortality for
intervention group at
1 year was 0.82.
Present value of net
benefits including
earnings from
productivity in
adulthood almost
$800.
Key: RCT – Randomised Controlled Trial; CEA – Cost-effectiveness Analysis; CBA – Cost-Benefit Analysis.
Perspective/price
year
Health sector
costs; impact on
future
productivity in
adulthood
International $
2003 prices
Appendix 4.8
Synthesis of
costs and
effectiveness
data
Overall the
present value of
lifetime benefits
was greater than
the present value
of costs of
intervention.
What are the effects of different models of delivery for improving maternal and infant health outcomes for poor people in urban areas in low income
and lower middle income countries?
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