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Full Report - Research for Development - Department for ...

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Author<br />

(year)<br />

(IV)/(EV)<br />

Aaby<br />

(2005)<br />

(++)/(+)<br />

Amin<br />

(1992)<br />

(-)/(-)<br />

Benn<br />

(2008a)<br />

(+)/(++)<br />

Benn<br />

(2008b)<br />

(++)/(++)<br />

Target<br />

Population<br />

Infants in<br />

general<br />

Infants in<br />

general<br />

Neonates in<br />

general<br />

Neonates in<br />

general<br />

Brief intervention description Targeted<br />

outcome(s)<br />

National immunisation days <strong>for</strong> oral polio<br />

vaccine (OPV) administered alone.<br />

Infant<br />

mortality<br />

Expanded Programme on Immunization (EPI). Infant<br />

mortality<br />

Infant vitamin A supplementation (VAS).<br />

Normal birthweight infants were<br />

administered 50,000 IU VAS or placebo with<br />

BCG.<br />

Infant VAS. Normal birthweight infants were<br />

administered 50,000 IU VAS or placebo with<br />

BCG.<br />

Infant<br />

mortality<br />

Infant<br />

mortality<br />

Findings summary<br />

Appendix 4.2<br />

OPV was associated with a beneficial effect<br />

<strong>for</strong> children under 6 months of age at the<br />

time of the campaign, but the difference<br />

was not significant <strong>for</strong> all children under 5<br />

years of age. The effect of OPV among<br />

children less than 6 months of age could be<br />

due to selection bias but might also<br />

represent a non-specific beneficial immune<br />

stimulation.<br />

There was a decline in infant mortality in<br />

1988-89 compared to earlier periods. The<br />

decline seemed to have been the result of<br />

immunisation coverage, which had<br />

considerably increased by 1989-90,<br />

reaching above 70% of children under age<br />

5.<br />

VAS administered with BCG vaccine at birth<br />

had no significant effect on infant mortality<br />

in this African setting.<br />

VAS administered with BCG vaccine at birth<br />

had no significant effect on infant mortality<br />

in this African setting.<br />

What are the effects of different models of delivery <strong>for</strong> improving maternal and infant health outcomes <strong>for</strong> poor people in urban areas in low income<br />

and lower middle income countries?<br />

211

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