Organohalogen concentrations and a gross and histologic ...

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198 Greenland. National Environmental Research Institute, Denmark. 31pp – NERI Technical Report No. 307. 2. Dietz R., C. Sonne-Hansen, E. W. Born, H. T. Sandell and B. Sandell (2001): Aberrant polar bears in East Greenland. An interview investigation, 1999 (with english summary). National Environmental Research Institute, Technical Report no. 359, pp. 50, www.neri.dk. 3. Sandell, H.T. , B. Sandell, E.W. Born, R. Dietz and C. Sonne-Hansen (2001): Polar bears in East Greenland. An interview investigation of occurence and hunt, 1999 (with english summary). Technical Report no. 40, Pinngortitaleriffik, Greenland Institute of Natural Resources, 96 pp., www.ginr.gl. 4. Sonne-Hansen, C., R. Dietz, F.F. Riget, E. W. Born, L. Hyldstrup and P. S. Leifsson (2003): Effects. Chapter 6. In: Riget, F. F., J. Christensen and P. Johansen (eds.). AMAP Greenland and the Faroe Islands 1997-2001. Ministry of Environment, Denmark. Oral workshop and conference presentations 1999-2004 1. Sonne-Hansen C., R. Dietz, P. S. Leifsson, L. Hyldstrup and F. F. Riget (1999): Cadmium toxicity to ringed seals (Phoca hispida). An epidemiological study of possible cadmium induced nephropathy and osteodystrophy in ringed seals (Phoca hispida) from Qaanaaq in Northwest Greenland. Eurotox Conference 99, Oslo, Norway, June 27-30, 1999. Poster presentation. 2. Dietz, R., G. Gabrielsen, C. Sonne-Hansen, A. Derocher, E.W. Born and H. Wolker (2000): Impact of Contaminants on European Arctic Polar Bears "ICEBEAR". Rovaniemi, Finland, January 18-20, 2000. Poster presentation. 3. Sonne-Hansen, C., R. Dietz, F. F. Riget, E. W. Born and M. Kierkegaard (2001): Contaminants in the Greenland Sea Polar Bear. The effect of persistent organic pollutants and new contaminants on internal endocrine organs and skulls in the East Greenland polar bear. NERI seminar 10.-12. Sept. 2001. Oral presentation. 4. Born, E.W., R. Dietz, C. Sonne-Hansen, H. Sandell and B. Sandell (2001): Aberrant polar bears in East Greenland, 14th Biennial Conference on the Biology of Marine Mammals, Vancouver, Canada november 23-2 december 2001. Poster presentation. 5. Mosbech, A., F. R. Merkel, A. Flagstad and C. Sonne-Hansen (2001): Satellite Tracking of King Eiders (Somateria spectabilis) in Western Greenland. Microwave Telemetry Conference 5.-7. Dec. in Columbia, MD, USA. Oral presentation. 6. Sonne-Hansen, C., R. Dietz, F. F. Riget, E. W. Born and M. Kierkegaard (2002): Contaminants in the Greenland Sea Polar Bear. The effect of persistent organic pollutants and new contaminants on internal and endo-
crine organs and skulls in the East Greenland polar bear. The international AMAP conference Jan. 2002. Oral presentation. 7. Dietz, R, F. F. Riget, C. Sonne-Hansen, P. S. Leifsson, L. Hyldstrup, E. W. Born, D. C. G. Muir, R. J. Letcher, G. Asmund and M. Kirkegaard (2002): Pollution of East Greenland polar bear around the millennium change. Second AMAP International Symposium on Environmental Pollution of the Arctic, Rovaniemi, Finland, 1 – 4 Oct. 2002. Oral presentation. 8. Sonne-Hansen, C., R. Dietz, F. F. Riget, E. W. Born and M. Kierkegaard (2003): Contaminants in the Greenland Sea Polar Bear. The effect of persistent organic pollutants and new contami-nants on internal and endocrine organs and skulls in the East Greenland polar bear. Ph.D. workshop, Department of Anatomy & Physiology, Copenhagen, Denmark, 7 Feb. 2003. Oral presentation. 9. Sandala, G. M., C. Sonne-Hansen, R. Dietz, D. C. G. Muir, E. R. Bennett and R. J. Letcher (2003): Methyl sulfone and hydroxylated PCB metabolites in adipose versus whole blood of polar bear (Ursus maritimus) from Scoresby Sound, Greenland. Canadian Arctic Contaminants Assessment Symposium, Ottawa, Canada, March 4-7, 2003. Poster presentation. 10. Kirkegaard, C. Sonne, P. S. Leifsson, R. Dietz, E. W. Born, R. J. Letcher and D. C. G. Muir (2004): Histology of selected immunological organs in East Greenland polar bears in relation to levels of organohalogens. 18th Annual Conference, European Cetacean Society, March 28.-31., Kolmården, Sweden, 2004. Poster presentation. 11. Merkel, F.R., Mosbech, A. and Sonne-Hansen, C. (2004): Habitat selection and foraging strategies of common Eiders wintering in south-west Greenland. Waterbirds around the World, A global review of the conservation, management and research of the world’s major flyways, Edinburgh, UK, 3-8 April, 2004. Poster presentation. 12. Mosbech, A., Merkel, F., Sonne-Hansen, C. and Gilchrist, G. (2004): Use of satellite telemetry to locate key habitats for King Eiders in Western Greenland. Waterbirds around the World, A global review of the conservation, management and research of the world’s major flyways, Edinburgh, UK, 3-8 April, 2004. Oral presentation. 199
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National Environmental Research Ins
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National Environmental Research Ins
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Contents Summary 7 Resumé 11 Prefa
Page 7 and 8:
Paper III-b Periodontitis and tooth
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Summary Marine mammals in the Arcti
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elations between histological chang
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Resumé Betydelige mængder svært
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signifikante relationer blev fundet
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Preface Since ca. 1960 signficant a
Page 19 and 20:
Acquarone, Poul Johansen and Inge B
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Abbreviations ∑ Sum of congeners
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Introduction Study area and samplin
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content and composition) varying wi
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Of the PCBs found in the East Green
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son Bay bears while the difference
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Individual levels and biological ef
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No. skulls collected 50 45 40 35 30
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temperature extremes and/or food av
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Chapter 3 Bone mineral density and
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BMD analysed by DXA reflects the ar
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Table 4 Range in the levels (ng/g l
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Chapter 4 Liver histology of East G
Page 45 and 46:
Table 7 Levels of ∑-PCBs, ∑-DDT
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Frequency (%) 100 80 60 40 20 Sever
Page 49 and 50:
Effects of PBBs (PolyBrominated Bip
Page 51 and 52:
Etiology and pathogenesis E Figure
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common sign (Acland 1995, Feldman 1
Page 55 and 56:
Conclusions and final assessments O
Page 57 and 58:
of CYP-450 activity that impact cir
Page 59 and 60:
Regarding renal tissue, we will try
Page 61 and 62:
Bernhoft, A., Ø. Wiig and J. U. Sk
Page 63 and 64:
Feldman, E. C. (1995): Hyperadrenoc
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(eds.): Ringed seals in the North A
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McCormack, K. M., W. M. Kluwe, V. L
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Rosing-Asvid, A., E. W. Born and M.
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Valentino, R., S. Savastano, A. P.
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Paper I Seasonal and temporal trend
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eproductive rates of seals in the B
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concentrations of the 41 individual
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Figure 1 Capture locations of the p
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Table 4 Results of ANOVAs (F-value
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Long-Term Temporal Changes in OC Co
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Discussion Geographical Variation i
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sen et al. (2001) studied the trend
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higher than reported in other studi
Page 91 and 92:
Bergman A, Olsson M. Pathology of b
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Muir D, Norstrom RJ. Geographical d
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Wiig Ø, Gjertz I, Hansson R, Thoma
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Key words: polar bear, Ursus mariti
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2. Materials and methods 2.1 Sampli
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2.3 Age Determination The age deter
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No. skulls collected 50 45 40 35 30
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Table 4 Results (test and p-values)
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Table 6 Results from F-tests (p-val
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(oxy-chlordane, trans-chlordane, ci
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Also Pertoldi et al. (1997) investi
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study could not document a relation
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Lie E, Bernhoft A, Riget FF, Beliko
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function in harbour seals (Phoca vi
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(p=0.94). Negative correlation betw
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Osteodensitometry X-ray osteodensit
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Figure 2 BMD (g cm 2 ) in skulls fr
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Table 3 Significant results from th
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2003) and plasma retinol and thyroi
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Comiso JC. 2002. A rapidly declinin
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Manalagas SC, Jilka RJ. 1995. Bone
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Valentine DW, Soulé M. 1973. Effec
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have the potential for adverse heal
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Dioxin-like contaminants Extraction
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Concentration 9000 8000 7000 6000 5
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Acknowledgements Danish Cooperation
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Polischuk, S. C., R. J. Letcher, R.
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Paper IV Liver histology of free-ra
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Histology All tissue samples were t
Page 149 and 150: Figure 1 Hepatic lipid accumulation
Page 151 and 152: Figure 2 Left: Portal mononuclear c
Page 153 and 154: Relationship between histology and
Page 155 and 156: kinson 1996). Due to these mechanis
Page 157 and 158: sues. Arctic Monitoring and Assessm
Page 159 and 160: van Duursen, M.B.M., Sanderson, J.
Page 161 and 162: Introduction Polar bears (Ursus mar
Page 163 and 164: Briefly, ∑PCBs is the sum (s) of
Page 165 and 166: Figure 1 Bottom: example of glomeru
Page 167 and 168: Figure 3 Tubular cell proliferation
Page 169 and 170: Hyalin casts Hyalin casts were eval
Page 171 and 172: Figure 6 Hyperemia (arrows) in the
Page 173 and 174: al., 2003). We did not find such a
Page 175 and 176: ANDERSEN, M., E. LIE, A. E. DEROCHE
Page 177 and 178: LUROSS, J. M., M. ALAEE, D. B. SERG
Page 179 and 180: organic mercury in liver and kidney
Page 181 and 182: Introduction Polar bears (Ursus mar
Page 183 and 184: Macroscopic examination of reproduc
Page 185 and 186: Results and discussion The female p
Page 187 and 188: SC II PC/LC Figure 2 The histology
Page 189 and 190: The relatively low levels of analys
Page 191 and 192: (Table 4), and we therefore conclud
Page 193 and 194: Acknowledgements Danish Cooperation
Page 195 and 196: Letcher RJ, Klasson-Wehler E, Bergm
Page 197 and 198: Swart RL, Ross PS, Vedder LJ, Timme
Page 199: 10. Heier, A., C. Sonne, A. Gröne,
Page 203: To investigate the relation between
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