ABstrACts ABstrACts 1308 analYSiS oF PUBmED- inDEXED aSTHma rESEarCH From THE araB WorlD in THE laST TEn YEarS Afifi, m. 1 and Hameed, W. A. 2 1 2 Primary Health Care, ministry of Health (HQ), <strong>Dubai</strong>, United Arab Emirates. Primary Health Care, ministry of Health, Ajman, United Arab Emirates. oBJECTiVES: We aimed to identify the gaps in asthma research in the Arab world and suggest recommendations for untapped areas. Hence we analyzed ten- years Pubmed- indexed publications related to bronchial asthma, produced by authors affiliated to the Arab countries. mETHoDS: a medline search was performed on 1st July 2010 to have the total number of citation from the 22 Arab countries during the ten years prior to the search. Another search in the mesH database of the medline for citations under “asthma” Or “ bronchial asthma” category was followed. the two search strategies were then combined by “AnD” and inspected for validation. the search was then saved in medline format text file, which was converted into Excel file and captured as a new database query via sPss software. the methodology of capturing research of the Arab countries and converting a medline search to an sPss data file was discussed in more details in previously published research by the first author. 1,2 rESUlTS: the number of asthma related publications affiliated to the Arab countries over the last 10 years totaled 275 articles. the number of research was doubled in 2010 relative to 2000. However, only three countries- namely KsA, Egypt and Kuwaitpublished 63% of the total publications. the three major areas studied were the epidemiological issues of asthma, its management, and its immunological issue (32%, 18.55%, and 18.05% respectively of total publications). Health system research constituted only 11.27% of publications. Areas as asthma in primary care and gender differences in morbidity and response to treatment are relatively neglected. the majority of publications were journal articles (82.9%), whereas clinical trial articles and evaluation studies constituted only 1.1 % and 3.6 % respectively. the saudi med J followed by J Asthma and Ann thorac med came on top of the list of 131 journals that published asthma research (12 %, 5.09% and 4.37% respectively). ConClUSion: Despite the increase in asthma publications, the outcome of some Arab countries was not satisfactory. Areas as health system research, asthma in primary care, and gender differences should have more consideration from Arab researchers. references: 1: Osman Ot, Afifi m. troubled minds in the gulf: mental health research in the United Arab Emirates (1989-2008). Asia Pac J Public Health. 2010 Jul;22(3 suppl):48s-53s. 2: Afifi mm. mental health publications from the Arab world cited in Pubmed, 1987-2002. East mediterr Health J. 2005 may;11(3):319-28. 1309 THE imPaCT oF ConComiTanT allErgiC rHiniTiS anD aSTHma on QUaliTY oF liFE in iTalian PaTiEnTS oF gEnEral PraCTiTionErS: arga STUDY maio, s. 1 , Baldacci, s. 1 , Borbotti, m. 1 , Angino, A. 1 , martini, F. 1 , Piegaia, B. 1 , silvi, P. 1 , sarno, g. 1 , Cerrai, s. 1 , simoni, m. 1 , Di Pede, F. 1 and Viegi, g. 2 1 2 institute of Clinical Physiology, national research Council, Pisa, italy. Cnr institute of Biomedicine and molecular immunology, Palermo, italy. Background: epidemiological studies show that allergic rhinitis is very common in patients with asthma, and that the co-presence of these two diseases can worsen the patients’ quality of life. aims: to evaluate the impact of the concomitance of asthma and rhinitis (Ar) on quality of life in italian patients of general practitioners (gP). methods: prospective observational study in different italian areas. 107 gP enrolled patients with asthma/rhinitis diagnosis and with anti-asthmatic or anti-rhinitic therapy or symptoms in the last 12 months. Questionnaires were used to collect data on respiratory allergic diseases. the rhinasthma questionnaire was used to assess the patients’ quality of life. Univariate analyses were used to assess the relationship between presence of only asthma, Ar or Ar and any one among other allergic diseases (sinusitis, conjunctivitis, atopic dermatitis and nasal polyposis) (ArOAD) and quality of life, disease severity levels and asthma symptoms. linear regression analysis was used to assess the relationship between quality of life and presence of Ar or ArOAD adjusting for age, gender, smoking habits and asthma severity levels. results: 46.8% of 936 subjects had only asthma, 36.2% Ar and 17.0% ArOAD. Univariate analyses showed a significantly higher frequency of moderate-severe asthma (36.0% vs 33.8%) and asthma symptoms (95.4% vs 89.9% for wheeze, 93.5% vs 88.7% www.worldallergy.org 102 FinAl PrOgrAm
ABstrACts for attacks of shortness of breath, 92.8% vs 85.4% for asthma symptoms in the last 12 month) in subjects with ArOAD with respect to those with only asthma; the presence of Ar or ArOAD, with respect to only asthma, was associated with a significantly worse quality of life (mean values of global score derived from rhinasthma questionnaire: 19.8±14.6, 20.2±14.3, 29.9±16.3, respectively). the multivariate linear regression analysis confirmed that the presence of Ar or ArOAD is an independent risk factor for a worse quality of life (beta coefficient: 0.253, p-value
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