Dubai Final-v20.indd - World Allergy Organization

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(30.3%), 4 (20%) e 40 (32%); in 89 F, 14 ms e 75 Ps, respectively 53 (67.6%), 44 ( 80%) and 9 (65.6%), with ri 35 (39.3%), 4
(38.6%) and 31 (41.3%): globally a little higher prevalence of m (ri+As), and of F ri particularly if ms. similar findings were found
relating (ri+As) to ss or Pr slit if ms and Ps. Conclusions
slit selection seems independent from sex, pathology and kind of sensitivity and is suitable for all seasonal antigens.
3206
a SUrVEY oF allErgEn SPECiFiC immUnoTHEraPY in KorEa
Hur, g. 1 , Kim, t. 2 , Han, m. Y. 3 , nahm, D. 4 and Park, J. 5
1 2 internal medicine, Korea University College of medicine, seoul, south Korea. Department of Allergy and Clinical immunology,
Asan medical Center, University of Ulsan College of medicine, seoul, south Korea. 3Pediatrics, Pochon CHA University College of
medicine, seoul, south Korea. 4Allergy & rheumatology, Ajou University school of medicine, seoul, south Korea. 5Division of Allergy
& immunology Department of internal medicine, Yonsei University College of medicine, seoul, south Korea.
Background; Allergen-specific immunotherapy (sit) has been used as the only curative and specific treatment for allergic
diseases. there have been no data on sit in Korea. therefore, we carried out a survey to observe the prescription pattern of allergy
specialists in Korea.
methods; All 690 members of the Korean Academy of Asthma, Allergy, and Clinical immunology received an e-mail attaching a
questionnaire on sit, and were required to return the answers. All returned answers were recruited between August 2009 and
september 2009.
results; the response rate was 21.0%. Among them, 42.8% was physicians, 32.4% was pediatricians, and 20.7% was
otolaryngologists. Only 69% of respondents performed sit in practice. the methods used to detect causative allergens were skin
prick test (46.1%) and serologic tests (44.1%) such as immunoCAP and mAst. the limitations to to start sit in their own practice
were lack of equipment (21%) and practical experience (15.8%), no necessary because pharmacotherapy alone was enough to
treat (14.5%), no good profit (14.5%), and its risks for adverse reactions (13.2%). the target diseases for sit were allergic rhinoconjunctivitis
(46%), allergic asthma (38%), and atopic dermatitis (10%). ninety-two allergic specialists (82%) performed sit via
subcutaneous route (sCit) and 18% via sublingual route (slit). the allergens used for sCit were house dust mites (42.5%), pollens
(31.3%), and animal dander (10.2%). twenty-eight (30%) doctors have experienced anaphylactic reaction during sCit. About 40%
of doctors have experienced any adverse reaction including local reactions during slit.
Conclusion; in Korea, 69% of allergy specialists performed sit in practice. the prevalence of sCit was 82% and slit was 18%.
lack of equipment and practical education were critical barrier to performing sit in doctors. therefore, proper practical educations
to update information on sit will be necessary for allergy specialists.
3207
SUCCESSFUl gamma-inTErFEron THEraPY in a CaSE oF rEFraCTorY VaCCinE-aSSoCiaTED aBSCESS in a CgD
PaTiEnT
nabavi, m. 1 , maherbanai, s. 1 and Bemanian, m. H. 2
1 2 semnan medical University, tehran, iran. Yazd medical university, Yazd, iran.
CgD is a rare phagocyte defect with an incidence of four to five per million individuals, caused by genes affecting one X-linked and
three autosomal recessive chromosomes. it is associated with recurrent abscesses of different size and locations. We present an 8
year old girl who developed large abscesses at her thigh since 2 years of age.
Case report:
the patient is an 8 year old girl who developed a large abscess at her thigh just at the site of childhood vaccinations when she was
2 years of age. the large 4×5-sized abscess contained voluminous yellow-greenish pus which led to persistent drainage. many
topical and systemic antibiotics were used without any result and multiple courses of hospitalizations with intravenous use
of wide-spread antibiotics had no benefits. gram stain and smear always showed a mixture of microbial agents for instance
staphylococcus, either s. alba or s.aureus. the abscess had 2 to 4 stoma apart from each other and sometimes locolation of pus
posed the need to incision and drainage of mutiple sites. Once acid fast bacilli were grown and anti tubercolosis medications
were prescribed and used for at least 9 months without any significant relief. Because of refractoriness of abscesses , phagocyte
defect were sugessted and an immunological consultation performed when she was 6 years of age. immunoglobulines were within
normal limits. nitro Blue tetrazolium (nBt) and Di Hydro rhodamine test (DHr) was performed and showed a significant defect
of respiratory burst and the patient regarded as “ Chronic granulomatous Disease”. long term therapeutic doses of trimetoprimsulfisoxazole
followed by continous prophylaxis, resulted to some relief. introduction of gamma- interferon as an every-other-day
schedule were terminally led to closure of abscess stoma and terminated the discharge. multiple scars of previously draining
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