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Dubai Final-v20.indd - World Allergy Organization

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ABstrACts<br />

mWCnts on OVA-asthma model were analyzed by airway hyperreactivity (AHr) measurement, bronchoalveolar lavage fluid (BAlF)<br />

analysis, intracellular rOs production and histological analysis in lung tissue.<br />

Results: intranasally administrated-mWCnts easily loaded in alveolar macrophage, but did not result in significant lung<br />

inflammation and intracellular rOs production of the OVA-induced asthma model. in histological analysis, mWCnts exacerbated<br />

collagen deposition within the lung parenchyma of naïve mice and pre-existing allergic mice.<br />

Conclusion: these results suggest that combined OVA sensitization and mWCnts administration did not affected pre-existing<br />

allergic, but increased collagen deposition in lung parenchyma.<br />

1111<br />

PollEn CoUnTS ProFilE in gEorgia EValUaTED BY THE BUrKHarD PollEn TraP<br />

Chikhladze, m. V. 1 and sepiashvili, r. i. 2<br />

1 2 national institute of Allergology, Asthma & Clinical immunology, georgian Academy of sciences, tskhaltubo, georgia. Department<br />

of Allergology and Clinical immunology, institute of immunophysiology, moscow, russia.<br />

Aim and Methodology: the pollen counts in georgia were studied in 2006-2009 using the vacuum Burkhard Pollen trap (great<br />

Britain) donated by the <strong>World</strong> <strong>Allergy</strong> <strong>Organization</strong> (WAO) to the national institute of Allergology, Asthma and Clinical immunology<br />

in tskhaltubo (georgia). the dependence of allergic diseases prevalence on the geographic location and some other factors (air<br />

temperature, humidity, height above the sea level, spectrum of regional plants) were also studied.<br />

Results: it was stated that allergy to mold fungi and other bacteria more often occurred in the areas with high humidity and the<br />

morbidity level with hay fever and bronchial asthma was much higher than in dry areas. in cities situated on the Black sea (Batumi,<br />

Kobuleti, Poti), ragweed is widely distributed, which in the period of blossom caused numerous allergic diseases (allergic rhinitis,<br />

conjunctivitis, urticaria etc.). When ragweed blossom, the quantity of pollen in the air is extremely high and as it is a strong allergen<br />

it causes exacerbation and allergic disease in people sensitized to ragweed pollen. the highest percentage of allergy morbidity<br />

fall at plants allergens caused by pollen of numerous weeds and plants (pollen of ragweed, alder, birch, maple, walnut, mallow,<br />

cotton-plant etc.). in different areas of georgia people are more sensitive to various plants. in imeretia region, it is ragweed pollen,<br />

in Kakhetia and Kartli – platan and wheat. graphic chart of hay fever and bronchial asthma morbidity as a rule have two peaks –<br />

spring–summer and autumn–winter. it is the season of plants blossom and the quantity of pollen in the air is most high.<br />

Conclusion: the pollen counts obtained using the Burkhard Pollen trap allowed us to make a pollen calendar for different regions<br />

of georgia thus enabling to perform treatment and prophylactic measures in advance.<br />

1112<br />

air PUriFiEr THaT USES PHoTo CaTalYTiC oXiDaTion rEDUCED THE PoPUlaTion oF mrSa<br />

ghosh, n. 1 , Pratt, C. 1 , Bennert, J. 2 , Chudasama, J. 2 and Das, A. B. 3<br />

1 2 3 life, Earth and Environmental sciences, West texas A&m University, Canyon, tX. Air Oasis, Amarillo. Dept. of Agricultural<br />

Biotechnology, College of Agriculture, Orissa University of Agriculture & technology, india.<br />

the air surrounding us plays an extremely important role in our well being and efficiency. Breathing pure and clean air allows us to<br />

think more clearly, sleep more soundly, and stay healthier. studies show that we receive 56% of our energy from the air we breathe,<br />

more than from water and food combined. On average we breathe 37 pounds of air a day. the quality of the environment within<br />

buildings is a topic of major importance for public health and indoor Air Quality (iAQ) is a major concern at work places. the objective<br />

of the present study was to assess two negative ion purifiers - Xtreme 3000 and luna induct air purifiers on the net reduction of<br />

bacteria in the microbiology and mycology laboratories of Baptist saint Anthony’s Hospital (BsA) in Amarillo, texas and the specific<br />

effect on methicillin resistant Staphylococcus aureus, mrsA. mrsA has become a serious public health issue. luna induct air units use<br />

an advanced hydrated Photo-Catalytic Oxidation (PCO) filtration system. it produces a broad spectrum high intensity UV light targeted<br />

on a quad metallic catalyst in a low-level ozone and moist atmosphere. Bacteria isolated from petri plates exposed to the room air<br />

were gram positive bacilli such as Bacillus, Coryneform (diptheroids), coagulase negative Staphylococcus and Micrococcus spp., and<br />

encapsulated gram negative bacilli. in every case there was reduction in airborne pathogen with variable room sizes when the air<br />

purifiers were used. tsA plates with 5% sheep blood were placed for exposure rooms at different distances and intervals. Plates were<br />

evaluated for the total number of bacterial and fungal colonies at intervals of 24, 48, 72 and 120 hours. We plated the mrsA strains<br />

from the stock culture after dilution 10-4 to investigate the effect of air-purifiers on the production of number of colonies of mrsA. tsA<br />

plates were inoculated with the strain after serial dilutions as follows. 5 ml of stock culture was diluted to 10-4 after incubation at 37o C for 24 hours and were plated onto tsA petri plates. ‘t-test’ results show that there was a significant difference in the air purifier<br />

treated sets and a gradual reduction in the number of colonies. the reduction of latent bacteria in the air could possibly reduce the<br />

transmission of airborne disease.<br />

www.worldallergy.org 83<br />

FinAl PrOgrAm<br />

ABstrACts

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