Dubai Final-v20.indd - World Allergy Organization

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both gender, suggesting a marked co-morbidity between asthma and ADHD. the association between AE and ADHD is modified
by sleeping problems which are, in itself, known risk factors to rtAs. given the significant morbidity and mortality of rtAs, atopic
disorders, and adult ADHD, the co- morbidity between these disorders should gain more attention from us. methods:
the aim of this presentation is to shed the light on the black spot in managing the aforementioned co- morbidity. the author
reviewed all publications investigating this co-morbidity in several databases.
results and conclusion:
then he would display in his 15 minutes oral presentation a black spot program to manage it.
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THE QUaliTY oF liFE in aSTHmaTiC PaTiEnTS TrEaTED WiTH omaliZUmaB
della torre, F. 1 , limonta, A. 1 , gaffuri riva, V. 1 and Della torre, E. 2
1 2 general Pneumology, inrCA-irCCs, milan, italy. internal medicine, san raffaele Hospital, milan, italy.
introduction
it is well known that some patients with severe persistent asthma remain inadequately controller despite receiving best available
treatment and optimal management efforts. such patients, who have exhausted the therapeutic options available to them , are at
risk of experiencing serious exacerbations and asthma related mortality
We present two cases treated with omalizumab
Case 1
35 years old female brasilian, ,work as housekeeper, with rhinitis and asthma since age 12. she experienced several hospital
admissions, frequent use of nebulizer, asthma worsening with numerous courses of iv and oral corticosteroids. skin prick tests
were positive to dermatophagoides, grass, birch, plantago. Fev1= 25% ( of predicted) reversing to 42%, total serum igE = 91 iU/ml.
she started Xolair in 2007 and after few months she improved her symptoms, reduced drugs and stopped with oral corticosteroids.
in 2009 she had no hospitalizations, can work normally. igE = 281 iU/ml, FEV1= 57% reversed to 71%. Her health has improved
and they are not so worried any more when she is out and about work and free time.
Case 2
severe persistent allergic asthma, 67 years old , severe asthma symptoms and exacerbations since 1980, ex smoker, ex
bricklayer, obesity, hypertension, diabetes mellitus. He had rhinitis and asthma due to allergy to mite and was treated with
subcutaneous specific immunotheraphy for 10 years with symptoms’ disappeared. since 2005 started with frequent asthma
exacerbations ( 5 times per year ) required emergency treatment or hospitalization. Exacerbations and symptoms limited his
activities of daily living, nocturnal symptoms, poor control despite maintenance oral steroids, inhaled steroids, salmeterol,
cromoglycate, theophylline trials and need long term oxygen theraphy.
in July 2007 skin prick test were positive for dermathophagoides, igE= 435 U/ml, FEV1 =70%. He started with Xolair treatment
and after two months stopped oral corticosteroids and after fourth months stopped oxygen therapy. in January 2010 FEV 1 =75%,
total serum igE : 494 iU/ml. improved symptoms, reduced wheezing shortness of breath, nocturnal symptoms uncommon. sleeps
through the night. Fewer exacerbations. no hospitalizations since starting xolair
Xolair doses were determined by serum total igE levels measured before treatment initiation and patient’s body weight. Dosing
tables were used to calculate the appropriate dose.
no side effects were reported.
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aToPiC aSTHma anD BronCHiECTaSiS
Khoury, A. 1 and Ahmed, F. 2
1 2 Chest Diseases, Aleppo Faculty of medicine, Aleppo, syria. Pulmonology Department, Faculty of medicine of Aleppo, Aleppo, syria.
Background:investigations using high-resolution Ct scan show that bronchiectasis is found in many patients with Asthma.
materials and methods: in our study we had investigated the presence of Bronchodilatation in 80 patients with stable atopic
Asthma and 20 healthy control subjects.
results: At least one dilated bronchus was present in 35 Patients(43,8%) and 1 control subject(5%).
Conclusion: We suggest to do HrCt-scan in Difficult to treat atopic asthma.
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