Dubai Final-v20.indd - World Allergy Organization
Dubai Final-v20.indd - World Allergy Organization
Dubai Final-v20.indd - World Allergy Organization
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ABstrACts<br />
ABstrACts<br />
treated with a relevant Oit protocol for nFA. As a control group 10 subjets received only iFn-gamma without allergenic food. 10<br />
subjets receive only food without iFn-gamma, and 20 subjets with nFA did not receive treatment. Patients were evaluated clinically<br />
after treatment using subcutaneous iFn-gamma injection.<br />
results: All patients became successfully tolerized to previously offensive foods (changes in clinical severity scores by food<br />
challenge from 15.9 ± 3.6 to 1.8 ± 1.0 points, p 0.05) in a group of only iFn-gamma treatment<br />
without food, from 14.6 ± 3.6 to 14.1 ± 3.0 points (p>0.05) in a group of only food challenge without iFn-gamma treatment, and<br />
from 15.9 ± 3.7 to 15.4 ± 4.3 points (p >0.05) in a untreated group with neither iFn-gamma nor food.<br />
Conclusions: non-igE-mediated food allergy can be successfully treated by relevant oral immunotherapy using iFn-gamma. iFngammaƒnseemed<br />
to be necessary for the tolerance induction.<br />
3210<br />
THE rolE oF immUnoTHEraPY in aSTHma anD rHiniTiS<br />
Hwejeh, l.<br />
Chest Department, AlAsAD UniVErsitY HOsPitAl in DAmAsCUD, Damascus, syria.<br />
immunotherapy (sit ) is the only currently available treatment that deals with the main cause of allergic disease by modifying the<br />
immune response<br />
Our study is a retrospective study in alasad university hospital in Damascus syria to identify the causative allergens and to evaluate<br />
the efficacy of immunotherapy .<br />
We studied 345 patients with well-documented history of rhinitis(68%) , or asthma (47%).<br />
140 patients received either sublingual or subcutaneous immune therapy and followed the protocol of sit.<br />
results showed 65.9% improvement in asthmatic patients with pollen allergy ,<br />
And 78% improvement in asthmatic patients with mites allergy.<br />
Patients with rhinitis due to mites allergy had 76.4% improvement<br />
While patients with rhinitis allergic to pollen had 70.1% improvement<br />
3211<br />
CHroniC aSTHma in aDUlTS<br />
Aguilar, D.<br />
mEDiCinE DiVisiOn, JUArEZ HOsPitAl, mexico DF, mexico.<br />
Alterations of forced vital capacity (FVC) and one-second forced expiratory volume (FEV1) forms part of the alterations present<br />
in chronic asthma. in an area that is aggressive for the health of the asthmatic patients as the city of mexico for its height, air<br />
pollution, overpopulation and migratory flows, the evolution of this disease to be different to other people living in other places<br />
with characteristics less damaging their environment. We used spirometry system to study 50 patients staying more than 5 years<br />
in the Valley of mexico<br />
with diagnosis of moderate persistent asthma. measurmenet made to that end of the values of FVC and FEVi in early morning<br />
without using bronchodilators and steroids systemic or topical. statistic : missing system. results: 35 females and 15 males,<br />
aged between 18 and 81 years old standard dev, in female 12.91, mean 39, standard dev. in male: 13.44, mean 35.5. He won<br />
the following most common pattern: Bronchial Hyperreactivity+ normal spirometry 39% in females. male sex in the peripheral<br />
moderate obstruction+ bronchial hyrresponsiveness in 33%. Conclusion: in both sexes the prevalence is the obstruction from mild,<br />
moderate and severe. most patients had bronchial hyperreactivity.<br />
3212<br />
SUBCUTanEoUS immUnoTHEraPY For TrEE PollEn allErgY WiTH a PrEParaTion WiTH oPTimiSED allErgEn<br />
alUminiUm HYDroXiDE raTio: an oPEn laBEl oBSErVaTional STUDY inVESTigaTing TolEraBiliTY anD<br />
EFFECTiVEnESS in THE roUTinE USE in DailY PraCTiSE<br />
neumann, U. 1 , Wolf, H. 2 , schnitker, J. 3 and Wuestenberg, E. g. 4<br />
1 2 3 Ent-Physician, Wolmirstedt, germany. Clinical Development, AlK-Abelló, Wedel, germany. institut für angewandte statistik,<br />
Bielefeld, germany. 4medical and regulatory Affairs, AlK-Abelló, Wedel, germany.<br />
Background: For subcutaneous immunotherapy (sCit) allergens usually are adsorbed to aluminium hydroxide (alum) for slow<br />
www.worldallergy.org 150<br />
FinAl PrOgrAm