Dubai Final-v20.indd - World Allergy Organization

ABstrACts
blood CD4+ t cells expressing mrnA encoding il-5 and il-4, and CD8+ t cells expressing il-5 mrnA. the data are compatible
with the hypothesis that clinical improvement associated with inhaled sCg therapy in childhood asthma results at least in part from
inhibition of elevated th2 cytokine synthesis by t cells.
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EConomiC CoST oF aDUlT aSTHmaTiCS in THE TErTiarY HoSPiTal oF KorEa
lee, s. 1 , Kim, t. 1 , Kang, H. 1 , Kim, s. 2 , Kim, s. 1 , lee, Y. 3 , Kim, t. 4 , Kim, s. 5 , Park, H. 1 , Park, s. W. 6 , Chang, Y. 2 , Cho, Y. s. 4 , Park, J. 7 ,
Cho, Y. J. 8 , Yoon, H. J. 5 , Cho, s. 1 , Choi, B. 9 , moon, H. 4 and min, K. 1
1 2 Department of internal medicine, seoul national University College of medicine, seoul, south Korea. Department of internal
medicine, seoul national University Bundang Hospital, seongnam, south Korea. 3Department of internal medicine, Yonsei University
College of medicine, seoul, south Korea. 4Department of Allergy and Clinical immunology, Asan medical Center, University of Ulsan
College of medicine, seoul, south Korea. 5Department of internal medicine, Hanyang University College of medicine, seoul, south
Korea. 6Division of respiratory and Allergy medicine, soonchunhyang University Hospital, College of medicine, Bucheon, south
Korea. 7Division of Allergy & immunology Department of internal medicine, Yonsei University College of medicine, seoul, south
Korea. 8Allergy and Clinical immunology, internal medicine, Ewha Womans University mockdong Hospital, seoul, south Korea.
9Department of internal medicine, Chung-Ang University College of medicine, seoul, south Korea.
Background: the prevalence of asthma is increasing and asthma cause a considerable socioeconomic burden worldwide.
However, few studies were conducted to evaluate the risk factors associated with economic cost of asthma in Korea. this study
was aimed to evaluate asthma cost according to severity and patients’ factors in the Korean tertiary hospital.
methods: Direct and indirect cost was assessed in the 314 physician-diagnosed adult asthmatics randomly recruited in eight
tertiary hospitals in Korea. Official direct medical cost was derived from the analysis of one-year(2009) expenditure related with
asthma-related hospital care utilization and medication. non-official direct cost(oriental medicine, instrument, and alternative
medicine) and indirect cost(productivity loss cost caused by hospital care utilization, work day loss and activity limitation) were
analyzed using a questionnaire designed for the study.
results: mean direct and indirect cost of the total subjects was estimated at 1,690 dollars and 1,503 dollars respectively.
multivariate analysis revealed that the most important risk factor affecting economic cost was asthma severity. Direct and indirect
cost were significantly higher in the severe persist asthma than in the mild to moderate persistent asthma (2,825 vs. 1,246
dollars, p=0.001, 3,734 vs. 594 dollars, p