Dubai Final-v20.indd - World Allergy Organization

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3319
PUlmonarY FUnCTion TEST in HEalTHY CHilDrEn 7 To 9 YEarS aFTEr rESPiraTorY Viral inFECTionS
Kartasasmita, iV, C. B. , sudarwati, s. , Wulandari, D. A. , suwardi, A. U. , saptaputra, W. , nuradi, i. , Kuswandewi, m. and simoes, E.
A.
Department of Child Health, Hasan sadikin/school of medicine Padjadjaran University, Bandung, indonesia, Bandung, indonesia.
Background. Pulmonary function test (PFts) provides an assessment of airflow limitation. it can be used for diagnosis of asthma in
children over 6 years of age. Viral infections during infancy can cause wheezing (roberg et al. 2007) and abnormal lung function
at 6 years of age (Anderson et al. 2008). the aim of this study is to determine the PFts in children 7 to 9 years after viral respiratory
infections.
materials and methods. this study is a part of a nested case control study entitled “rsV and recurrent wheezing in indonesia:
7 – 9 year follow-up study with lung function studies”. the PFts were obtained from December 2009 to July 2010. All the
children were healthy when the PFts were performed. to determine the obstructive impairment we analyzed FEV1 and FEV1/
FVC ratio. reversibility was measured in children with % predictive FEV1 < 80%, before and after administration of a short acting
bronchodilator.the FEV1/FVC ratio > 80% showed normal lung function.
results. A total 218 children, age 8.4 to 13.4 years old (mean 10.5 ± 1.05 years), consisted of 111 boys and 107 girls, were
enrolled in the study. Fifty two cases with history of viral respiratory infections, and 166 controls. the viral pathogens found were:
rsV (25), rV (19), mix rsV and rV (6), and hmPV (2). the mean ± sD of FEV1 in cases (2.12 ± 0.42) was slightly higher than
control (2.04 ± 0.39), however, the difference was statisticaly not significant. the mean ± sD FEV1/FVC ratio in cases (90.76 ±
9.15) and in control (92.28 ± 6.5) were also statisticaly no difference. in 14 out of 218 (6.4%) children the reversibility test were >
12%.
Conclusion: the PFts in children with history of viral respiratory infections are within normal limit, 7 to 9 years later. the rate of
asthma is low.
3320
CliniCal ProFilE anD riSK FaCTorS in HoSPiTaliZED CHilDrEn WiTH BronCHioliTiS
Kirovski, i. , nikolovski, l. , sazdovski, A. , micevska, V. and seckova, l.
Department of Pulmonology and Allergology, University Children’s Hospital, skopje, macedonia.
Bronchiolitis, potentially life-threatening respiratory condition is the most common reason for hospitalization in infancy.
the aim of the study was to determine the risk factors and to describe the clinical profile in children who were admitted to the
hospital with a diagnosis of bronchiolitis.
methods: We studied 153 children, the analysis we conducted was restricted to first hospitalizations within the first 18 months. Data
from their medical records were entered in a specially designed questionnaire. the following data were analyzed: age on admission,
gender, gestational age, association of bronchiolitis with children’s nutritional status. Clinical factors such as chronic lung disease
and congenital heart disease (CHD) were investigated. socioeconomic status, possible exposure to passive smoking, family history
of atopy, number of siblings were also investigated. the respiratory rate, oxygen saturation, presence of chest wall retractions and
cyanosis upon admission were noted.
results: Of the 153 patients 85 were males and 68 females, giving a male to female ratio of 1,25:1. sixty-six percent were
under 9 months of age and were previously healthy children. We could not find significant association between bronchiolitis and
nutritional status. shorter or lack of exclusive breastfeeding was a risk factor for the hospitalization. 37% of the children were
passive smokers. socioeconomic status was a factor in increasing the risk of hospital admission in our patients. Prevalence rate
for bronchiolitis was higher in rural areas compared to urban ones. Other factors, such as a diagnosis of bronchodysplasia, CHD,
and prematurity were not significantly associated with being hospitalized for bronchiolitis. the best method for initial assessment of
bronchiolitis was oxygen saturation.
Conclusion: the youngest infants and those who have been exposed to cigarette smoke after birth have the highest risk of
bronchiolitis. the association between socioeconomic factors and hospitalization indicates that these factors may have a significant
influence on the hospitalization rate in bronchiolitis during infancy. the promoting of exclusive breastfeed ing is for prevention of
infectious diseases and also because of the lesser aggressive course of bronchiolitis in breastfed children.
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