Dubai Final-v20.indd - World Allergy Organization

ABstrACts
result
the patient was diagnosed as relapsing polychondritis (rP) and treated with prednison 2 mg/kg of bodyweight/day. the next
bronchoscopy showed that the patient’s airway became narrowed, so we added immunosupressive agent (methotrexate), started
from 10 mg/week. After the patient got methotrexate for 6 weeks, there was a clinical improvement and the tracheoscopy
examination showed that the karina, the right and left prime bronchus was opened, and no evidence of granulation.
Conclusion
steroids alone did not give good result as expected, but the combination with methotrexate in this patient was proved useful and
gave better clinical improvement.
Key word: Collagen type ii, laryngotracheomalacia, methotrexate, relapsing polychondritis
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PEriPHEral EoSinoPHilia
restrepo, m. 1 , Diez, s. 1 , sanchez, J. 1 , Chinchilla, C. 2 and Cardona, r. 3
1 2 Allergology, Universidad de Antioquia, medellín, Colombia. University of Antioquia - grupo de Alergología Clínica y Experimental
(gACE), medellin, Colombia. 3University of Antioquia, medellin, Colombia.
Background: the accumulation of eosinophils in a variety of tissues is not unique to host defense or as result of immune
dysregulation, this buildup occurs as a strategy to maintain homeostasis in both states: health and disease. Eosinophilia is
considered to occur when the total number of eosinophils in the periphery is significantly higher than considered normal for the
general population
objective: to present the clinical case of a patient with peripheral eosinophilia, which one did not show apparent trigger.
medical history and monitoring: 5 years old male patient, evaluated by our allergy group for 3-month history of cervical
lymphadenopathy associated with fever, current edema in hands and feet and itchy, his laboratory test revealed eosinophils
between 1860 and 9500cell/ml. studies were conducted to rule out to rule out causes of peripheral eosinophilia. HiV, toxocara, CmV,
toxoplasma antibodyes has done , cerebrospinal fluids cytology, igE, bone marrow biopsy, echocardiography, upper gastrointestinal
endoscopy, colonoscopy and biopsies all within normal ranges.
By peripheral eosinophilia, recurrent fever and swelling hands gleich syndrome was thought , which is characterized by recurrent
episodes of angioedema, urticaria, itchy, fever, weight gain, elevated igm and leukocytosis with marked eosinophilia. requested
to continue with the studios vit B12 levels, igm, skin biopsy with immunohistochemistry and serum levels of tryptase, Finding
high levels of Vit B12: 1018 pg / ml, normal tryptase and igm. skin biopsy was not carried out because the skin symptoms and
eosinophilia resolved.
it highlights the need for diagnostic studies in patients with hypereosinophilia in order to reach an etiological diagnosis. in our
patient suspected gleich syndrome, but the normalization of the eosinophil count four months after without drug treatment and
the absence of physical signs, now ruled out the diagnosis and force us to make periodic checks.
Bibliography: the eosinophilias, including the idiopathic hypereosinophilic syndrome. Briito Babapulle. J Haematol 2003.
Eosinophilia and Eosinophil-related Disorders Peter F. Weller middleton’s Allergy: Principles and Practice, 7th ed.n
PoSTEr SESSion 2-2: Drug and food allergy
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PoTEnTial aDVErSE rEaCTionS From ComPlEmEnTarY anD alTErnaTiVE mEDiCinE (Cam) anD DiETarY SUPPlEmEnT
(DS) in norTH amEriCa
Wong, H. g.
Department of medicine, University of British Columbia & Vancouver general Hospital, Vancouver, BC, Canada.
Background: Complementary and alternative medicine (CAm) and dietary supplement (Ds) being natural products, are usually
considered harmless. Potential adverse reactions in four preparations are presented.
method: Visits were made to Chinese herbal shops and health food stores in Vancouver, Canada, and new York, UsA. the
ingredients of some CAm and Ds were carefully examined.
results: Four preparations, two from Vancouver (1,2) and two from new York (3,4) were noted to have potential adverse reactions.
1. ArtHO-ACE “pill for pain relief” with a label stating “this product is made from [ten] selected natural herbal [sic] and contains no
toxin [sic] & chemicals.” Does it mean it may contain heavy metal or pharmaceutical product?
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