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Physical fitness training for stroke patients (Review) - Update Software

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Ryan<br />

Trial name or title Inflammation and exercise in <strong>stroke</strong><br />

Methods Randomised clinical trial; parallel assignment; open label<br />

Participants 150 participants expected<br />

Ischaemic or haemorrhagic <strong>stroke</strong> greater than or equal to 6 months prior with stable residual hemiparetic<br />

gait deficits<br />

Already completed all conventional inpatient and outpatient physical therapy<br />

Interventions Intervention: cardiorespiratory <strong>training</strong><br />

Control: stretching<br />

Outcomes Body composition, VO2 peak<br />

Starting date Start: May 2009<br />

Completion: April 2014<br />

Contact in<strong>for</strong>mation Dr Alice S. Ryan, University of Maryland, VA Research Service, USA<br />

Tel 410-605-7851, Email aryan@grecc.umaryland.edu<br />

Notes NCT00891514 (same as Ivey (A)?)<br />

Suskin 2007<br />

Trial name or title Cardiac rehabilitation <strong>for</strong> TIA <strong>patients</strong> (CR-TIA)<br />

Methods Randomised clinical trial, parallel assignment; single blind (outcomes assessor)<br />

Participants 200 participants<br />

Inclusion criteria: age > 20 years; documented TIA or mild non-disabling <strong>stroke</strong> within the previous 3 months;<br />

at least 1 of the following vascular risk factors: hypertension, ischaemic heart disease, diabetes mellitus,<br />

dyslipidaemia or cigarette smoking<br />

Exclusion criteria: inability to speak or understand English or provide in<strong>for</strong>med consent; severe aphasia that<br />

renders communication difficult or impossible; Modified Rankin Scale score of greater than or equal to 3;<br />

Mini Mental State Examination score ≤ 20; evidence of intracranial haemorrhage confirmed by CT scan<br />

or MRI study; anticipated or recent (< 30 days) carotid endarterectomy, angioplasty and/or stenting; resides<br />

> 1 hour travel time from London or Ottawa; prior participation in a CCR program; inability to per<strong>for</strong>m<br />

expected exercise <strong>training</strong> of CCR program; evidence of cardioembolic source <strong>for</strong> TIA/<strong>stroke</strong> such as atrial<br />

fibrillation, valvular disease, septal defect or left ventricular wall motion abnormality; participation in another<br />

clinical trial that could interfere with the intervention or outcomes of the current study<br />

Interventions Intervention: comprehensive CCR program plus usual care (include home-based exercise 2 days/week <strong>for</strong> 6<br />

months)<br />

Control: usual care alone<br />

Outcomes Primary outcome measures: functional capacity; lipid profile; depression symptoms; cognition<br />

Secondary outcome measures: cerebrovascular and cardiovascular events; physiological, anthropometric and<br />

behavioral vascular risk factors; neurocognitive measure; quality of life<br />

<strong>Physical</strong> <strong>fitness</strong> <strong>training</strong> <strong>for</strong> <strong>stroke</strong> <strong>patients</strong> (<strong>Review</strong>)<br />

Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.<br />

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