Thursday-Abstracts

Official Journal of the American College of Sports Medicine
1469 Board #61 May 30, 3:30 PM - 5:00 PM
Paleolithic diet and Exercise suppress hunger during Inter-
Meal Interval By different Mechanisms
Po-Ju Lin, Katarina Borer. University of Michigan, Ann Arbor, MI.
(No relationships reported)
Both exercise and higher fat and protein diet have been shown to reduce hunger ratings
compared to high carbohydrate diet or sedentary condition. To find out whether this
effect has a common mechanism, we examined how Paleolithic (P) versus Western diet
(W), and exercise (X) versus sedentary (S) condition affected hunger ratings. Gastric
inhibitory polypeptide (GIP) secretion and acetaminophen (APAP) absorption as a
marker of gastric emptying (GE) served as a measure of gastrointestinal food transit
(GFT). Although GIP has not been implicated in the control of hunger, GIP could
affect hunger ratings indirectly by changing GE.
PurPOsE: Examine the effect of P and W meal on hunger ratings and plasma GIP
and APAP concentrations during X or S condition.
METhOds: Twenty-four healthy postmenopausal women participated in 1 of 4
conditions: S or 2 h of X (14 to 16 h) with P or W meal (PS, PX, WS, WX; n=8 each).
The P meal contained 30% carbohydrate (CHO), 25% protein (PRO), and 45% FAT
while W meal contained 60% CHO, 15% PRO, and 25% FAT. The meal was provided
at 10 h. Participants were provided 20ml of liquid acetaminophen (160mg/5ml),
30 minutes after the start of the meal. Plasma GIP and APAP concentrations were
measured, and hunger ratings assessed with a visual analog scale, at hourly intervals
during 3 h after the start of exercise. Changes in hunger ratings, GIP and APAP
concentrations were analyzed with repeated measures mixed model ANOVA.
rEsuLTs: Hunger ratings were overall significantly higher after W than after P meal
(F=10.3, p