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Thursday-Abstracts

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<strong>Thursday</strong>, May 30, 2013<br />

S192 Vol. 45 No. 5 Supplement<br />

FINAL WORKING DIAGNOSIS:<br />

Plantar fibromatosis (fibroproliferative condition on the plantar fascia tissue)<br />

TrEaTMENT aNd OuTCOMEs:<br />

1. Immediate reduction of running workouts to within a pain free range.<br />

2. Two treatment sessions per week for four weeks within an athletic training facility<br />

incorporating an instrument-assisted-soft-tissue mobilization technique.<br />

3. Low intensity strengthening exercises and passive stretching were performed during<br />

treatment sessions.<br />

4. A home exercise program was prescribed on days when the patient was not treated<br />

by the clinician.<br />

5. Returned to full participation in running at week four of treatments with full, pain<br />

free ROM, pain free running gait and decreased size of the plantar fibroma by 17%<br />

(0.37cm 2 ).<br />

6. Patient successfully completed the half-marathon race, pain free and at goal pace<br />

1-month following the conclusion of treatment.<br />

C-24 Free Communication/Poster - Advances in<br />

Exercise Immunology<br />

May 30, 2013, 7:30 AM - 12:30 PM<br />

Room: Hall C<br />

1056 Board #1 May 30, 8:00 AM - 9:30 AM<br />

Endurance-training Effects On Intracellular Calcium and<br />

Iron In Cd4 + Lymphocytes In young and Old Men<br />

Suzanne Broadbent. Southern Cross University, Lismore NSW,<br />

Australia.<br />

(No relationships reported)<br />

Intracellular calcium (Ca 2+ i )and iron (Fe 3+ i) are critically involved in intracellular<br />

signalling within CD4 + cells yet little is known of long-term exercise effects on these<br />

variables in relation to CD4 + activation and proliferation.<br />

PurPOsE: To investigate the effects of 12 months of aerobic/endurance exercise<br />

on Ca2+i and Fe3+i concentrations within CD4+ lymphocytes in old and young men<br />

compared to sedentary controls.<br />

METhOds: We compared young (30±5 yr) trained (TRY, n=14) and sedentary (UTY,<br />

n=12) men to older (69±5 yr) trained (TRO, n=14) and sedentary (UTO, n=10) men for<br />

12 months. The TRY group completed daily endurance training (60-120 min day, 60-<br />

80% VO 2peak ) while the TRO group cycled for three 60 min sessions per week (60-75%<br />

VO 2peak ). Venous blood was analysed every month for resting lymphocyte counts. CD4 +<br />

cells were separated and stimulated with thapsigargin to quantify Ca 2+ i, using Fluo-3<br />

AM and flow cytometry. Further CD4 + lymphocytes were incubated with Calcein AM<br />

to assess Fe 3+ i.<br />

rEsuLTs: The TRY group had a significantly higher CD4+ concentration than<br />

UTY for 4 months (37±7%, p

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