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<strong>Thursday</strong>, May 30, 2013<br />

S336 Vol. 45 No. 5 Supplement<br />

compared to 85% VO2max (2.54 ± 0.73 vs. 2.01 ± 0.45 ml min-1 mmHg-1, resp).<br />

CVC increased (p 0.05) for both conditions. The amount of RMF was related (r=0.61; p 0.05)<br />

between the ΔFEV1% pre-post exercise and %EFL at VO2max. However, in children<br />

MEDICINE & SCIENCE IN SPORTS & EXERCISE ®<br />

that demonstrated clinically relevant EIB (i.e.,>10% decrease in FEV1; n=22), there<br />

was a significant relationship (r = 0.66, p < 0.05) between EIB and EFL. In study<br />

two (n=16), with training, children improved pre-post exercise ΔFEV1% (pre:-7.60 ±<br />

2.10%, post:-1.10 ± 1.80%, p < 0.05). There was an association between ΔFEV1% and<br />

Δ%EFL from pre- to post-training (r = 0.77, p < 0.05) in the TRG only.<br />

CONCLusION: These data suggest that pre-adolescent children who exhibit<br />

clinically relevant EIB also demonstrate the most severe expiratory flow limitation<br />

during exercise. With exercise training, reductions in EIB are associated with reduced<br />

EFL. These findings may be important in prevention and treatment of exercise<br />

intolerance in pre-adolescent children.<br />

1746 Board #4 May 30, 3:15 PM - 5:15 PM<br />

Peak Oxygen uptake differs Between Obese Women With<br />

Vs. Without dyspnea On Exertion<br />

J. Todd Bassett, Vipa Bernhardt, Santiago Lorenzo, Raksa<br />

B. Moran, Sarah F. Haller, Jessica M. Pineda, Tony G. Babb,<br />

FACSM. Institute for Exercise and Environmental Medicine,<br />

Texas Health Presbyterian Hospital Dallas and University of<br />

Texas Southwestern Medical Center, Dallas, TX.<br />

(No relationships reported)<br />

PurPOsE: During constant load exercise, some otherwise healthy obese women<br />

experience dyspnea on exertion (+DOE), while others do not (-DOE). In previous<br />

studies, we observed exercise capacity to be similar in -DOE and +DOE. We<br />

questioned whether this would remain true if we sampled a larger number of obese<br />

women.<br />

METhOds: To investigate, we recruited 80 otherwise healthy obese women who<br />

were divided into groups based on their Ratings of Perceived Breathlessness (RPB,<br />

Borg 0-10 scale) at the end of 6 minutes of constant load cycling (60W), as in prior<br />

studies. 24 women were designated as -DOE (RPB≤2, 32±8 yr, 37±4 BMI, mean±SD)<br />

and 34 women were classified as +DOE (RPB≥4, 34±7 yr, 36±5 BMI). 22 women<br />

with RPB=3 were excluded to better delineate the groups. Peak oxygen uptake was<br />

determined during maximal incremental cycle ergometry. Data were analyzed between<br />

groups by independent t-test. The relationship between variables was determined by<br />

linear regression analysis.<br />

rEsuLTs: While peak oxygen uptake was within normal limits in both groups,<br />

exercise capacity (as % of predicted) was greater (p

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