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Official Journal of the American College of Sports Medicine<br />

ERS guidelines. Maximal inspiratory and expiratory pressures were also determined.<br />

Data were analyzed between groups by independent t-tests. The relationships between<br />

variables were determined by linear regression analysis.<br />

rEsuLTs: There were no meaningful relationships between pulmonary function<br />

parameters and RPB during constant load cycling within the groups or when<br />

combined. Differences in maximal voluntary ventilation between the -DOE (112±13)<br />

and +DOE (104±15) groups approached significance (p=0.0553). Only maximal<br />

expiratory pressure reached significance (p=0.0258) between the groups (108±26<br />

%predicted and 94±22, respectively).<br />

CONCLusION: As in previous studies, pulmonary function, with only a few<br />

exceptions, does not differ between otherwise healthy obese women without vs. with<br />

DOE.<br />

Supported by NIH Grant Funding #HL096782 and The King Charitable Foundation<br />

Trust.<br />

1748 Board #6 May 30, 3:15 PM - 5:15 PM<br />

Impact of Expiratory Flow Limitation on Performance at<br />

simulated altitude<br />

Joshua C. Weavil, Jonathon L. Stickford, Joseph W. Duke,<br />

Robert F. Chapman, FACSM, Joel M. Stager, FACSM, Timothy<br />

D. Mickleborough, FACSM. Indiana University, Bloomington,<br />

IN.<br />

(No relationships reported)<br />

Many athletes exhibit expiratory flow limitation (FL) during heavy exercise and<br />

consequently may be additionally challenged when exercising at moderate altitude.<br />

PurPOsE: To determine how FL affects aerobic performance at modest altitude.<br />

We hypothesized that NFL athletes will be at a competitive advantage where altitudeinduced<br />

declines in SaO2 present less of a consequence than the coincident increases<br />

in ventilation and work of breathing experienced by the non-flow limited athlete.<br />

METhOds: Flow limited (FL n=7) and non-flow limited (NFL n=7) male cyclists<br />

performed three 5-km time trials on a Velotron cycle ergometer on separate days.<br />

Expired gases were measured at rest and throughout each time trial. Participants<br />

performed a familiarization trial followed by a single-blinded normoxic (FiO 2 = 0.21)<br />

and hypoxic (FiO 2 = 0.17, approximately 2000m altitude) trial in random order. Time to<br />

completion (T TT ) and average power output (P TT ) were used to assess performance.<br />

rEsuLTs: Metabolic, ventilatory, and performance measures were similar between<br />

groups (FL vs. NFL) in normoxia. However, when comparing the normoxic and<br />

hypoxic trials, the FL group had a significantly smaller (p

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