Thursday-Abstracts

Thursday, May 30, 2013
S212 Vol. 45 No. 5 Supplement
C-29 Free Communication/Poster - Epidemiology
of Physical Activity and Cardiovascular
Disease and Cardio Fitness
May 30, 2013, 7:30 AM - 12:30 PM
Room: Hall C
1137 Board #82 May 30, 8:00 AM - 9:30 AM
Cardiorespiratory Fitness, Muscular strength, and
Mortality
Duck-chul Lee1 , Gregory J. Welk, FACSM 1 , Warren D. Franke,
FACSM 1 , Xuemei Sui2 , Steven N. Blair, FACSM 2 . 1Iowa State
University, Ames, IA. 2University of South Carolina, Columbia, SC.
(No relationships reported)
PurPOsE: To determine the independent and combined associations of
cardiorespiratory fitness (CRF) and muscular strength (MS) with all-cause mortality.
METhOds: Participants comprised 7,492 men aged ≥20 years (mean age 42) who
had a medical examination during 1980-1989 in the Aerobics Center Longitudinal
Study. They were free of cardiovascular disease (CVD), cancer, and had ≥85% of their
age-predicted maximal heart rate on a treadmill test and ≥1 year of follow-up. CRF,
in metabolic equivalents (METs), was estimated from a maximal treadmill test. MS
was measured by 1 repetition maximums of bench and leg presses and a composite
MS score was computed by combining the standardized values of both tests. We
used tertiles of the age-specific METs and strength scores. Further, CRF and MS
were dichotomized into either fit or strong (upper two-thirds), or unfit or weak (lower
one-third) in a joint analysis of CRF and MS with mortality. Mortality follow-up was
through 2003 using the National Death Index. Cox regression models included baseline
age, body mass index, smoking status, alcohol drinking, medical conditions, parental
CVD, and MS score for CRF or METs for MS.
rEsuLTs: During an average follow-up of 18.5 years, 400 deaths occurred. The
hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality were 0.82 (0.65-
1.04), and 0.69 (0.52-0.93) in middle and upper CRF categories, and 0.73 (0.58-0.93)
and 0.74 (0.57-0.95) in middle and upper MS categories, respectively, compared with
each lower category after adjusting for confounders and MS or CRF for each other.
In the joint analysis, compared with unfit and weak group, HRs (95% CIs) were 0.54
(0.40-0.74) in unfit and strong group, 0.60 (0.43-0.83) in fit and weak group, and
0.53 (0.41-0.69) in fit and strong group. In age-stratified analyses, the strength of the
association between CRF and mortality was similar in age-groups of 40-49, 50-59,
and ≥60 years. However, MS was getting more strongly associated with mortality with
increasing age, especially in age groups of 50-59 and ≥60 years.
CONCLusION: Both CRF and MS are independent predictors of mortality. The
increased importance of MS with age should be considered when promoting exercise
for seniors.
Supported by NIH Grant AG06945, HL62508, DK088195, and an unrestricted
research grant from The Coca-Cola Company.
1138 Board #83 May 30, 8:00 AM - 9:30 AM
Cardiorespiratory Fitness and Incidence Of urolithiasis:
retrospective Cohort study Of Japanese Men
Susumu S. Sawada, FACSM1 , Ryoko Kawakami1 , Takashi
Okamoto2 , Koji Tsukamoto2 , I-Min Lee, FACSM3 , Steven Blair,
FACSM4 , Motohiko Miyachi1 . 1National Institute of Health and
Nutrition, Tokyo, Japan. 2Tokyo Gas Co. LTD.,, Tokyo, Japan.
3 4 Harvard Medical School, Boston, MA. University of South
Carolina, Columbia, SC.
(No relationships reported)
Physical movement with physical activity and water intake after exercise or sport
may enhance the early release of urinary tract stone(s). Cardiorespiratory fitness is
an objective marker of habitual physical activity or exercise/sports. However, to our
knowledge, there is no paper focusing on the relationship between cardiorespiratory
fitness and incidence of urolithiasis.
PurPOsE: To investigate the association between cardiorespiratory fitness and
incidence of urolithiasis among Japanese males.
METhOds: We evaluated the cardiorespiratory fitness and incidence of urolithiasis
of 4,074 Japanese men [median (IQR) age31 (28-35) years]. Participants were given
a submaximal exercise test, a medical examination, and questionnaires on their health
habits in 1985. Cardiorespiratory fitness was measured using a cycle ergometer test,
and maximal oxygen uptake was estimated. The development of urolithiasis was based
on self-reports from questionnaires at a subsequent medical examination in 2004.
Relative risks and 95% confidence intervals (95%CI) for incidence of urolithiasis were
obtained using Cox proportional hazard models.
rEsuLTs: During follow-up period 258 participants developed urolithiasis.
Following age adjustments, and using the lowest cardiorespiratory fitness (1st tertile)
MEDICINE & SCIENCE IN SPORTS & EXERCISE ®
group as a reference, the relative risks (95%CIs) for 2nd and 3rd tertiles were: 0.93
(0.67-1.26) and 0.75 (0.54-1.03), respectively; p for trend = 0.08. After adjusting for
body mass index, cigarette smoking, and alcohol intake, the relative risks (95%CIs)
were: 1.01 (0.74-1.39), 0.84 and (0.59-1.19), respectively; p for trend = 0.32.
CONCLusIONs: These findings suggest that cardiorespiratory fitness is not a
predictor of incidence of urolithiasis in Japanese men. However, it is possible that only
high-impact exercises, such as jogging, running, or jumping rope, affect the incidence
of urolithiasis. Thus, research into the relationship between these specific exercises and
the incidence of urolithiasis should be examined in the future.
1139 Board #84 May 30, 8:00 AM - 9:30 AM
relationship Between risk Factors for Cardiovascular
disease in undergraduate students and Body Composition
Henry H. Leon Ariza1 , Aura C. Zea Robles1 , Walter E. Rodriguez
Alvarez2 . 1Universidad Santo Tomás, Bogotá, Colombia.
2Louisville University, Louisville, KY.
(No relationships reported)
Cardiovascular disease (CVD) is the leading cause of death worldwide with
approximately 17 million deaths per year. This situation is getting worse in part due
to the increasing prevalence of metabolic syndrome, obesity and physical inactivity in
youth.
PurPOsE: to assess the prevalence of major risk factors for CVD including tobacco
use, high blood pressure (BP), high blood glucose (HBG), lipid abnormalities (LA),
obesity, and physical inactivity, in a population of first-year undergraduate students at
the University of Santo Tomas (Colombia).
METhOds: We conducted a study of prevalence of risk factors for CVD with a
random sample of 192 healthy students (94 women and 99 men), who were 16 to
22 years old. Participants answered a survey to assess nutritional habits, lifestyle
and stress. Glucose, total cholesterol, high density lipoproteins (HDL), low density
lipoproteins (LDL), and triglycerides (TG) were measured in blood to assess HBG and
LA risk factors. Resting BP was measured to evaluate the risk factor of high BP. Waist
circumference, height and weight were measured; and the percentages of body fat
and muscle mass were calculated by bioelectrical impedance analysis (BIA). Pearson
correlations were used (level of significance of p18% (50.0%) and HDL-C23%
(56.3%), LDL-C ≥ 100 mg/dl (50.3%), and HDL-C 0.21. Interestingly, there was a
relationship between the AIx and anthropometric factors, such as body mass index
(BMI) (0.48 p