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Protocol for the Derivation of Environmental and Human ... - CCME

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Part B, Section 7<br />

ingestion (SQG I ) should ensure that ingestion <strong>of</strong> <strong>the</strong> soil <strong>and</strong> ingestion <strong>of</strong> plants growing on that soil does<br />

not result in <strong>the</strong> animal receiving more than 75% <strong>of</strong> <strong>the</strong> DTED:<br />

(exposure from soil + exposure from food) = 0.75 * DTED [1]<br />

For soil ingestion, <strong>the</strong> exposure is equal to <strong>the</strong> concentration in soil multiplied by <strong>the</strong> soil ingestion rate<br />

(SIR) <strong>and</strong> a bioavailability factor <strong>and</strong> divided by <strong>the</strong> body weight <strong>of</strong> <strong>the</strong> animal exposed:<br />

Exposure from soil ingestion = SQG I × SIR × BF [2]<br />

BW<br />

Where SQG I = soil quality guideline <strong>for</strong> soil <strong>and</strong> food ingestion (mg kg -1 )<br />

SIR = soil ingestion rate (kg dw soil/day)<br />

BF = bioavailability factor (unitless)<br />

BW = body weight (kg)<br />

Likewise, <strong>for</strong> food ingestion, <strong>the</strong> exposure is equal to <strong>the</strong> concentration in food multiplied by <strong>the</strong> food<br />

ingestion rate (FIR) <strong>and</strong> a bioconcentration factor <strong>and</strong> divided by <strong>the</strong> body weight <strong>of</strong> <strong>the</strong> animal<br />

exposed:<br />

Exposure from food ingestion = SQG I * FIR * BCF [3]<br />

BW<br />

Where SQG I = soil quality guideline <strong>for</strong> soil <strong>and</strong> food ingestion (mg kg -1 )<br />

FIR = food ingestion rate (kg dw food/day)<br />

BCF = bioconcentration factor (unitless)<br />

BW = body weight (kg)<br />

Equations (2) <strong>and</strong> (3) can be incorporated into equation (1) to provide <strong>the</strong> following equation:<br />

SQG I × SIR × BF + SQG I × FIR × BCF = 0.75 DTED [4]<br />

BW<br />

BW<br />

Finally, equation (4) can be rearranged to give <strong>the</strong> final equation <strong>for</strong> deriving a soil quality guideline <strong>for</strong><br />

ingestion (SQG I ) that will prevent grazing animals from being exposed to more than 75% <strong>of</strong> <strong>the</strong> DTED<br />

resulting from <strong>the</strong> ingestion <strong>of</strong> soil <strong>and</strong> plants:<br />

SQG I = 0.75 × DTED × BW [5]<br />

(SIR × BF) + (FIR × BCF)<br />

where,<br />

SQG I = soil quality guideline <strong>for</strong> soil <strong>and</strong> food ingestion (mg/kg dw soil)<br />

DTED = daily threshold effects dose (mg/kg bw⋅day)<br />

72

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