Protocol for the Derivation of Environmental and Human ... - CCME
Protocol for the Derivation of Environmental and Human ... - CCME
Protocol for the Derivation of Environmental and Human ... - CCME
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Part B, Section 7<br />
ingestion (SQG I ) should ensure that ingestion <strong>of</strong> <strong>the</strong> soil <strong>and</strong> ingestion <strong>of</strong> plants growing on that soil does<br />
not result in <strong>the</strong> animal receiving more than 75% <strong>of</strong> <strong>the</strong> DTED:<br />
(exposure from soil + exposure from food) = 0.75 * DTED [1]<br />
For soil ingestion, <strong>the</strong> exposure is equal to <strong>the</strong> concentration in soil multiplied by <strong>the</strong> soil ingestion rate<br />
(SIR) <strong>and</strong> a bioavailability factor <strong>and</strong> divided by <strong>the</strong> body weight <strong>of</strong> <strong>the</strong> animal exposed:<br />
Exposure from soil ingestion = SQG I × SIR × BF [2]<br />
BW<br />
Where SQG I = soil quality guideline <strong>for</strong> soil <strong>and</strong> food ingestion (mg kg -1 )<br />
SIR = soil ingestion rate (kg dw soil/day)<br />
BF = bioavailability factor (unitless)<br />
BW = body weight (kg)<br />
Likewise, <strong>for</strong> food ingestion, <strong>the</strong> exposure is equal to <strong>the</strong> concentration in food multiplied by <strong>the</strong> food<br />
ingestion rate (FIR) <strong>and</strong> a bioconcentration factor <strong>and</strong> divided by <strong>the</strong> body weight <strong>of</strong> <strong>the</strong> animal<br />
exposed:<br />
Exposure from food ingestion = SQG I * FIR * BCF [3]<br />
BW<br />
Where SQG I = soil quality guideline <strong>for</strong> soil <strong>and</strong> food ingestion (mg kg -1 )<br />
FIR = food ingestion rate (kg dw food/day)<br />
BCF = bioconcentration factor (unitless)<br />
BW = body weight (kg)<br />
Equations (2) <strong>and</strong> (3) can be incorporated into equation (1) to provide <strong>the</strong> following equation:<br />
SQG I × SIR × BF + SQG I × FIR × BCF = 0.75 DTED [4]<br />
BW<br />
BW<br />
Finally, equation (4) can be rearranged to give <strong>the</strong> final equation <strong>for</strong> deriving a soil quality guideline <strong>for</strong><br />
ingestion (SQG I ) that will prevent grazing animals from being exposed to more than 75% <strong>of</strong> <strong>the</strong> DTED<br />
resulting from <strong>the</strong> ingestion <strong>of</strong> soil <strong>and</strong> plants:<br />
SQG I = 0.75 × DTED × BW [5]<br />
(SIR × BF) + (FIR × BCF)<br />
where,<br />
SQG I = soil quality guideline <strong>for</strong> soil <strong>and</strong> food ingestion (mg/kg dw soil)<br />
DTED = daily threshold effects dose (mg/kg bw⋅day)<br />
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