Protocol for the Derivation of Environmental and Human ... - CCME
Protocol for the Derivation of Environmental and Human ... - CCME
Protocol for the Derivation of Environmental and Human ... - CCME
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Appendix B<br />
Appendix B<br />
Checking <strong>Protocol</strong> <strong>for</strong> Contaminated Ingestion Resulting<br />
from Produce, Meat, <strong>and</strong> Milk Produced at Remediated<br />
Residential <strong>and</strong> Agricultural Sites<br />
1.0 Background <strong>and</strong> Application<br />
<strong>Human</strong>s can be indirectly exposed to contaminants in soils through food-chain contamination <strong>of</strong><br />
produce, meat, <strong>and</strong> milk. For agricultural l<strong>and</strong> use, it is likely that some meat, produce (i.e.,<br />
vegetables), <strong>and</strong> milk will be produced <strong>and</strong> consumed on-site. In <strong>the</strong> residential setting, it is also<br />
possible that a backyard garden may provide a significant portion <strong>of</strong> <strong>the</strong> produce consumed by a family.<br />
To ensure that soil remediation guidelines do not result in an unacceptable contribution to total daily<br />
intake <strong>of</strong> contaminants via homegrown produce, meat, <strong>and</strong> milk, it is necessary to compare <strong>the</strong><br />
expected intake <strong>of</strong> contaminants from <strong>the</strong>se sources with <strong>the</strong> total intake.<br />
The concentration estimated to occur in food from soils contaminated at <strong>the</strong> preliminary soil guideline<br />
concentration must be less than <strong>the</strong> maximum residue limit (MRL) published under <strong>the</strong> Food <strong>and</strong> Drug<br />
Act. If no MRL exists <strong>for</strong> <strong>the</strong> chemical under study, <strong>the</strong>n <strong>the</strong> total daily intake estimated by <strong>the</strong><br />
procedure outlined in this appendix must not exceed total background exposure from food (i.e.,<br />
estimated daily intake) by more than 20% <strong>of</strong> <strong>the</strong> difference between <strong>the</strong> TDI <strong>and</strong> <strong>the</strong> EDI, <strong>for</strong> noncarcinogens.<br />
For carcinogens, total contaminant intake must not exceed <strong>the</strong> risk specific dose (RSD)<br />
<strong>for</strong> a cancer risk <strong>of</strong> 10 -6 .<br />
The procedure <strong>and</strong> assumptions <strong>for</strong> estimating <strong>the</strong> concentration <strong>of</strong> a contaminant in food <strong>and</strong> daily<br />
intake is described in Section 1.1. The protocol provides an estimate <strong>of</strong> bioconcentration <strong>of</strong><br />
contaminants into, <strong>and</strong> consumption <strong>of</strong>, <strong>the</strong>se foods, in relation to <strong>the</strong> assumptions outlined in Section<br />
1.1. This procedure applies only to non-polar organic contaminants. Methods <strong>for</strong> <strong>the</strong> assessment <strong>of</strong><br />
<strong>the</strong> bioconcentration <strong>of</strong> metals, or o<strong>the</strong>r chemicals not typically known to bioaccumulate, should be<br />
considered on a chemical-by- chemical basis.<br />
No detailed data about <strong>the</strong> proportion <strong>of</strong> food Canadians consumed from local origin are available.<br />
However, it is believed to be a substantial contribution to total daily intake, especially in an agricultural<br />
setting. For example, a 1985 survey in Quebec indicates that 42% <strong>of</strong> urban residents, <strong>and</strong> 58% <strong>of</strong> rural<br />
residents consume vegetables from <strong>the</strong>ir own gardens (MAPAQ, 1985). The proportion may vary<br />
considerably from one location to ano<strong>the</strong>r. Generally however, it should reflect <strong>the</strong> variations relating to<br />
<strong>the</strong> type <strong>of</strong> environment considered (i.e.,urban, rural or suburban) <strong>and</strong> it is also unlikely that <strong>the</strong>se foods<br />
will be consumed over <strong>the</strong> entire year.<br />
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