Protocol for the Derivation of Environmental and Human ... - CCME
Protocol for the Derivation of Environmental and Human ... - CCME
Protocol for the Derivation of Environmental and Human ... - CCME
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Part B, Section 2<br />
2.3 Endpoint Definition<br />
Suter (1993) describes two basic types <strong>of</strong> endpoints used in ecological risk assessment: assessment <strong>and</strong><br />
measurement endpoints. Assessment endpoints are <strong>for</strong>mal expressions <strong>of</strong> <strong>the</strong> environmental values to<br />
be protected (Suter, 1989) (e.g., decline in soil arthropod abundance). Two steps are required to<br />
properly define <strong>the</strong>se endpoints in a research project:<br />
• identifying <strong>the</strong> valued attributes <strong>of</strong> <strong>the</strong> environment considered to be at risk, <strong>and</strong><br />
• defining <strong>the</strong>se attributes in operational terms (Suter, 1993).<br />
Suter (1993) indicated that <strong>the</strong>re is no universal set <strong>of</strong> assessment endpoints, but that <strong>the</strong>re are five<br />
criteria that any endpoint should satisfy:<br />
• societal relevance,<br />
• biological relevance,<br />
• unambiguous operational definition,<br />
• accessability to prediction <strong>and</strong> measurement, <strong>and</strong><br />
• susceptibility to <strong>the</strong> hazardous agent.<br />
Examples <strong>of</strong> assessment endpoints are given in Suter (1993), who recommends that <strong>the</strong> a<strong>for</strong>ementioned<br />
criteria be seriously considered when operationally defining assessment endpoints so that ecological<br />
effects assessment is effective <strong>and</strong> understood at <strong>the</strong> societal level.<br />
Measurement endpoints are measurable, quantifiable responses (e.g., LC 50 ) to a chemical stressor that<br />
is related to a valued attribute <strong>of</strong> <strong>the</strong> ecological component (Suter, 1990). These measurable responses<br />
are usually estimated in monitoring studies <strong>of</strong> laboratory toxicity tests <strong>and</strong> are generally referred to as<br />
indicators (Suter, 1993). Since it is <strong>of</strong>ten difficult to measure assessment endpoints most data are used<br />
quantitatively or qualitatively. Assessment <strong>and</strong> measurement endpoints are seldom <strong>the</strong> same since<br />
assessment endpoints are usually defined on a large scale (e.g., populations, ecosystems) <strong>and</strong><br />
measurement endpoints on an individual level. Never<strong>the</strong>less, measurement endpoints should be<br />
consistent with assessment endpoints (e.g., predictions on population decline based on mortality<br />
estimates). Examples <strong>of</strong> measurement endpoints related to assessment endpoints are given in Suter<br />
(1993).<br />
In terrestrial toxicity testing, most data focused on mortality (LC 50 ) as a short-term endpoint <strong>and</strong><br />
reproduction, growth, development, behaviour, activity, lesions, physiological changes, respiration,<br />
nutrient cycling, contribution to decomposition, genetical adaption, <strong>and</strong> physiological acclimatization as<br />
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