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Protocol for the Derivation of Environmental and Human ... - CCME

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7.2 Evaluation <strong>of</strong> Laboratory <strong>and</strong> Field Toxicological Data.......................................................40<br />

7.2.1 Laboratory Data...............................................................................................................40<br />

7.2.2 Field Data.........................................................................................................................42<br />

7.3 Minimum Toxicological Data Requirements........................................................................42<br />

7.4 <strong>Environmental</strong> Behaviour Considerations ...........................................................................43<br />

7.5 <strong>Derivation</strong> <strong>of</strong> Soil Quality Guidelines <strong>for</strong> Soil Contact.........................................................43<br />

7.5.1 Overview..........................................................................................................................43<br />

7.5.2 Methods <strong>for</strong> Agricultural <strong>and</strong> Residential/Parkl<strong>and</strong> L<strong>and</strong> Uses............................................43<br />

7.5.2.1 Using Microbial (Nutrient <strong>and</strong> Energy Cycling) Data <strong>for</strong> <strong>Derivation</strong> <strong>of</strong> Soil<br />

Contact Guidelines <strong>for</strong> Agricultural <strong>and</strong> Residential/Parkl<strong>and</strong> L<strong>and</strong> Use ..............................46<br />

7.5.2.2 Weight <strong>of</strong> Evidence Method..............................................................................................46<br />

7.5.2.3 Lowest Observed Effect Concentration Method................................................................47<br />

7.5.2.4 Median Effects Method.....................................................................................................48<br />

7.5.2.5 Insufficient Data <strong>for</strong> Soil Contact Guidelines <strong>Derivation</strong>......................................................49<br />

7.5.3 Methods <strong>for</strong> Commercial <strong>and</strong> Industrial L<strong>and</strong> Use .............................................................49<br />

7.5.3.1 Overview..........................................................................................................................49<br />

7.5.3.2 Using Microbial (Nutrient <strong>and</strong> Energy Cycling) Data <strong>for</strong> <strong>Derivation</strong> <strong>of</strong> Soil<br />

Contact Guidelines <strong>for</strong> Commercial <strong>and</strong> Industrial L<strong>and</strong> Use ..............................................49<br />

7.5.3.3 Weight <strong>of</strong> Evidence Method..............................................................................................52<br />

7.5.3.4 Lowest Observed Effect Concentration Method................................................................52<br />

7.5.3.5 Insufficient Data <strong>for</strong> Soil Contact Guidelines <strong>Derivation</strong>......................................................53<br />

7.6 <strong>Derivation</strong> <strong>of</strong> Soil Quality Guidelines <strong>for</strong> Soil <strong>and</strong> Food Ingestion........................................53<br />

7.6.1 Determining <strong>the</strong> Daily Threshold Effects Dose....................................................................54<br />

7.6.1.1 Determining <strong>the</strong> Species Most at Threat from Soil <strong>and</strong> Food Ingestion................................54<br />

7.6.1.2 Calculation <strong>of</strong> <strong>the</strong> Daily Threshold Effects Dose.................................................................54<br />

7.6.2 Determining Body Weight .................................................................................................56<br />

7.6.3 Determining <strong>the</strong> Rate <strong>of</strong> Soil Ingestion................................................................................56<br />

7.6.4 Determining <strong>the</strong> Rate <strong>of</strong> Food Ingestion.............................................................................56<br />

7.6.5 Determining Bioavailability.................................................................................................57<br />

7.6.6 Determining Bioconcentration Factors ...............................................................................57<br />

7.6.7 Calculation <strong>of</strong> <strong>the</strong> Soil Quality Guideline <strong>for</strong> Soil Ingestion..................................................58<br />

Section 8<br />

<strong>Derivation</strong> <strong>of</strong> <strong>the</strong> Final <strong>Environmental</strong> Soil Quality Guidelines..................................................62<br />

8.1 Agricultural L<strong>and</strong> Use .......................................................................................................62<br />

8.2 Residential/Parkl<strong>and</strong> L<strong>and</strong> Use..........................................................................................62<br />

8.3 Commercial <strong>and</strong> Industrial L<strong>and</strong> Use.................................................................................62<br />

PART C<br />

Section 1<br />

<strong>Derivation</strong> <strong>of</strong> <strong>Human</strong> Health Soil Quality Guidelines.................................................................65<br />

1.1 Introduction......................................................................................................................65<br />

1.2 Guiding Principles <strong>for</strong> Establishing <strong>Human</strong> Health Soil Quality Guidelines............................67<br />

1.3 Uncertainty in Guidelines <strong>Derivation</strong>...................................................................................67<br />

xiv

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